DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3277 and Fgfrl1

DIOPT Version :9

Sequence 1:	NP_608762.3	Gene:	CG3277 / 33543	FlyBaseID:	FBgn0031518	Length:	789	Species:	Drosophila melanogaster
Sequence 2:	NP_473412.1	Gene:	Fgfrl1 / 116701	MGIID:	2150920	Length:	529	Species:	Mus musculus

Alignment Length:	212	Identity:	42/212 - (19%)
Similarity:	71/212 - (33%)	Gaps:	51/212 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   195 GKCSCQLAPTPPKVLAVAKMLSNETISINLSILASELLRKEQDSHLHETL---------RTYKMQ 250
            ||.:|:              :||:..:||.:.....:.|......|..|.         .|...|
Mouse   213 GKYTCR--------------VSNKAGAINATYKVDVIQRTRSKPVLTGTHPVNTTVDFGGTTSFQ 263

  Fly   251 LKINEETNPSLPWGGVLKHLMTRVYKLSELNFRAT-PKGFEGVMKLGLGTQLKEKASLSLQAVII 314
            .|:..:..|.:.|       :.||...||....:| ..|.:..:.|..|..........|..::|
Mouse   264 CKVRSDVKPVIQW-------LKRVEYGSEGRHNSTIDVGGQKFVVLPTGDVWSRPDGSYLNKLLI 321

  Fly   315 -----DPTG---CEGPRS---------VTKVPVPANPVLLTEGDSVSNSI---IVMSAMLIAIIL 359
                 |..|   |.|..:         :|.:|.|..|.......|.|.|:   :|:.....|:.:
Mouse   322 SRARQDDAGMYICLGANTMGYSFRSAFLTVLPDPKPPGPPMASSSSSTSLPWPVVIGIPAGAVFI 386

  Fly   360 AGLIMLLLRRRRARTTA 376
            .|.::|.|.:.:.:..|
Mouse   387 LGTVLLWLCQTKKKPCA 403

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3277	NP_608762.3	STYKc	426..763	CDD:214568
CG3277	NP_608762.3	PTKc	430..763	CDD:270623
Fgfrl1	NP_473412.1	I-set	29..112	CDD:369462
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	116..151
		Ig2_FGFRL1-like	153..234	CDD:143264	7/34 (21%)
		Ig	257..351	CDD:386229	19/100 (19%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	405..427
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0200
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900