Protein Alignment CG15406 and ITR1

DIOPT Version :10

• Sequence 1: NP_608761.2
• Gene: CG15406 / 33542
• FlyBaseID: FBgn0031517
• Length: 469
• Species: Drosophila melanogaster
• Sequence 2: NP_010785.1
• Gene: ITR1 / 852108
• SGDID: S000002905
• Length: 584
• Species: Saccharomyces cerevisiae
• Alignment Length: 502
• Identity: 111/502 - (22%)
• Similarity: 191/502 - (38%)
• Gaps: 105/502 - (20%)

  Fly    22 SLSATLIT---------FCHGIALGWLSPML--------PKLLSPQETPLSFYIDVNEASWLGAV 69
            |||..:||         |..|...|::|..|        .|:|:..|..:     |..|:.|||:
Yeast    81 SLSPFIITLTFVASISGFMFGYDTGYISSALISIGTDLDHKVLTYGEKEI-----VTAATSLGAL 140

  Fly    70 IS--IGGISGNFSFSYLMNRFGRKVSIYALAVPHTCIWFLFYFAQSIEWLYVARVFAGLTGGGMF 132
            |:  ..|.:.:.        ||||..:....:.......|...|.:...:.|.|:..|...|...
Yeast   141 ITSIFAGTAADI--------FGRKRCLMGSNLMFVIGAILQVSAHTFWQMAVGRLIMGFGVGIGS 197

  Fly   133 VVLPIFIGEIADNSIRGRLCSFFTLTMNTGIMVGFVVSSHIAY-----------HVIP------- 179
            ::.|:||.|||...|||||....:|.:..|.:|.:...:.:.|           .:||
Yeast   198 LIAPLFISEIAPKMIRGRLTVINSLWLTGGQLVAYGCGAGLNYVNNGWRILVGLSLIPTAVQFTC 262

  Fly   180 -CAVVGLPVLYVL----------LATRYPEPPQQLIRWKREEEAEKSLRYYRRCDGPNVSKEEER 233
             |.:...|..||:          |...|.:..:::|    |.:.|:.:...:...|.||   .|:
Yeast   263 LCFLPDTPRYYVMKGDLARATEVLKRSYTDTSEEII----ERKVEELVTLNQSIPGKNV---PEK 320

  Fly   234 AYQKHFDEMRLAIQQQNNDTDDNGLSMSDFLTKRSLKALATGLVLMVANIFTGTFAFNNYMSNIF 298
            .:.        .|::.:.             ...:|:||..|..|.....|||..:...:...||
Yeast   321 VWN--------TIKELHT-------------VPSNLRALIIGCGLQAIQQFTGWNSLMYFSGTIF 364

  Fly   299 DAVHTQLDPNTNTIIIGAVQILGTLASIYLVDRYGRKILLIVSCAGSGIGTSAFGLYAFYAEEQK 363
            :.|..: :.:..:||:.....:.||.:.:.:|:.||:.:|::...|..:......: ||:....|
Yeast   365 ETVGFK-NSSAVSIIVSGTNFIFTLVAFFSIDKIGRRTILLIGLPGMTMALVVCSI-AFHFLGIK 427

  Fly   364 VD-------LSAFSAWLPVTLMAFIIFIA----NVGVISVTMVVLVEILPQKIRAVATSFCLGCL 417
            .|       .|.||:|..|.::..|:|.|    .:|.:....   .|:.||.:|.:.||:.....
Yeast   428 FDGAVAVVVSSGFSSWGIVIIVFIIVFAAFYALGIGTVPWQQ---SELFPQNVRGIGTSYATATN 489

  Fly   418 SFFAFASLKTFPLMMFHLGLAATMWFCAAVSVICLFYVVVCLEETKG 464
            ...:.....||..|:.::..|.|..|.|.:|.:...:...|..|..|
Yeast   490 WAGSLVIASTFLTMLQNITPAGTFAFFAGLSCLSTIFCYFCYPELSG 536

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG15406	NP_608761.2	MFS_GLUT6_8_Class3_like	19..469	CDD:340916	111/502 (22%)
ITR1	NP_010785.1	MFS_HMIT_like	92..533	CDD:340918	104/486 (21%)