Protein Alignment CG15406 and SLC2A8

DIOPT Version :10

• Sequence 1: NP_608761.2
• Gene: CG15406 / 33542
• FlyBaseID: FBgn0031517
• Length: 469
• Species: Drosophila melanogaster
• Sequence 2: XP_047279239.1
• Gene: SLC2A8 / 29988
• HGNCID: 13812
• Length: 599
• Species: Homo sapiens
• Alignment Length: 476
• Identity: 129/476 - (27%)
• Similarity: 209/476 - (43%)
• Gaps: 72/476 - (15%)

  Fly    33 GIALGWLSPMLPKLLSPQETPLSFYIDVNEASWLG-----------------AVISIGGISGNFS 80
            |.:.|.||| ||........|.||..:...:.|.|                 ||:::|..:|...
Human   145 GTSTGPLSP-LPLPSGRARGPGSFTSEPAGSGWRGRMGCGFGAPSSAAARLQAVVTLGAAAGGVL 208

  Fly    81 FSYLMNRFGRKVSIYALAVPHTCIWFLFYFAQSIEWLYVARVFAGLTGGGMFVVLPIFIGEIADN 145
            ..:|::|.|||:|:...:||....:.:...||.:..|...|:..||..|...:|.|::|.|||..
Human   209 GGWLVDRAGRKLSLLLCSVPFVAGFAVITAAQDVWMLLGGRLLTGLACGVASLVAPVYISEIAYP 273

  Fly   146 SIRGRLCSFFTLTMNTGIMVGFVVSSHIAYHVIPCAVVGL--PVLYVLLATRYPEPPQQLIRWKR 208
            ::||.|.|...|.:..||::.::....:.:..:  ||:|.  |.|.:||....||.|:.|:...|
Human   274 AVRGLLGSCVQLMVVVGILLAYLAGWVLEWRWL--AVLGCVPPSLMLLLMCFMPETPRFLLTQHR 336

  Fly   209 EEEAEKSLRYY----RRCDGPNVSKEEERAYQKHFDEMRLAIQQQNNDTDDNGLSMSDFLTKRSL 269
            .:||..:||:.    :..:.|.:..|:         ...||:.:|      .|:          .
Human   337 RQEAMAALRFLWGSEQGWEDPPIGAEQ---------SFHLALLRQ------PGI----------Y 376

  Fly   270 KALATGLVLMVANIFTGTFAFNNYMSNIFDAVHTQLDPNTNTIIIGAVQILGTLASIYLVDRYGR 334
            |....|:.||.....:|..|...|...||:....: |.:..::::|.:|:|.|..:..::||.||
Human   377 KPFIIGVSLMAFQQLSGVNAVMFYAETIFEEAKFK-DSSLASVVVGVIQVLFTAVAALIMDRAGR 440

  Fly   335 KILLIVSCAGSGIGTSAFGLY--------------AFYA--EEQKVDLSAFSAWLPVTLMAFIIF 383
            ::||::|.......|||||.|              |..|  ..|.||.|...|||.|..|.  :|
Human   441 RLLLVLSGVVMVFSTSAFGAYFKLTQGGPGNSSHVAISAPVSAQPVDASVGLAWLAVGSMC--LF 503

  Fly   384 IAN--VGVISVTMVVLVEILPQKIRAVATSFCLGCLSFFAFASLKTFPLMMFHLGLAATMWFCAA 446
            ||.  ||...:..:::.||.|..::.|||..|:......||...|.|..:|..|......|..:|
Human   504 IAGFAVGWGPIPWLLMSEIFPLHVKGVATGICVLTNWLMAFLVTKEFSSLMEVLRPYGAFWLASA 568

  Fly   447 VSVICLFYVVVCLEETKGRSM 467
            ..:..:.:.:.|:.||||:::
Human   569 FCIFSVLFTLFCVPETKGKTL 589

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG15406	NP_608761.2	MFS_GLUT6_8_Class3_like	19..469	CDD:340916	129/476 (27%)
SLC2A8	XP_047279239.1	PHA03307	3..>196	CDD:223039	12/51 (24%)
		MFS	36..591	CDD:475125	129/476 (27%)