Protein Alignment CG15406 and SLC2A13

DIOPT Version :10

• Sequence 1: NP_608761.2
• Gene: CG15406 / 33542
• FlyBaseID: FBgn0031517
• Length: 469
• Species: Drosophila melanogaster
• Sequence 2: NP_443117.3
• Gene: SLC2A13 / 114134
• HGNCID: 15956
• Length: 648
• Species: Homo sapiens
• Alignment Length: 571
• Identity: 115/571 - (20%)
• Similarity: 208/571 - (36%)
• Gaps: 146/571 - (25%)

  Fly    16 RRQL----------LVSLSATLITFCHGIALGWLS-PMLPKLLSPQETPLSFYIDVNEASWLGAV 69
            |||.          :|::.:.|..|..|...|.:| .||  ||..|.:..:.:.::..:|.:||.
Human    69 RRQFQQDETPAFVYVVAVFSALGGFLFGYDTGVVSGAML--LLKRQLSLDALWQELLVSSTVGAA 131

  Fly    70 ISIGGISGNFSFSYLMNRFGRKVSIYALAVPHTCIWFLFYFAQSIEWLYVARVFAGLTGGGMFVV 134
             ::..::|    ..|...|||:.:|...:...|....:...|.:.|.|...|:..||..|...:.
Human   132 -AVSALAG----GALNGVFGRRAAILLASALFTAGSAVLAAANNKETLLAGRLVVGLGIGIASMT 191

  Fly   135 LPIFIGEIADNSIRGRLCSFFTLTMNTGIMVGFVVSSHIAY------------HVIPCAVVGLPV 187
            :|::|.|::..::||||.:..||.:..|.....||....:|            ..:|..:.....
Human   192 VPVYIAEVSPPNLRGRLVTINTLFITGGQFFASVVDGAFSYLQKDGWRYMLGLAAVPAVIQFFGF 256

  Fly   188 LYVLLATRYPEPPQQLIRWKREEEAEKSLRYYRRCDGPNVSKEEERAYQKHFDEMRLAIQQQNND 252
            |::      ||.|:.||:..:.::|.:.|...|    .|.:.:||      :|.::..|:::..:
Human   257 LFL------PESPRWLIQKGQTQKARRILSQMR----GNQTIDEE------YDSIKNNIEEEEKE 305

  Fly   253 TDDNGLSMSDFL----TKRSLKALATGLVLMVANIFTGTFAFNNYMSNIFDAVHTQLDPNTNTII 313
            ....|..:...|    |:|   ||..|..|.:....:|......|.:.|...  :.::.:...|.
Human   306 VGSAGPVICRMLSYPPTRR---ALIVGCGLQMFQQLSGINTIMYYSATILQM--SGVEDDRLAIW 365

  Fly   314 IGAV----QILGTLASIYLVDRYGRKILLIVSCAGSGI--------------------------- 347
            :.:|    ..:.||..::||::.||:.|...|.||:.:
Human   366 LASVTAFTNFIFTLVGVWLVEKVGRRKLTFGSLAGTTVALIILALGFVLSAQVSPRITFKPIAPS 430

  Fly   348 GTSAFGLYAFYAEE----------QKVDLSAF--SAWLPVT------------------------ 376
            |.:|......|..|          .|::.|..  |:.:||.
Human   431 GQNATCTRYSYCNECMLDPDCGFCYKMNKSTVIDSSCVPVNKASTNEAAWGRCENETKFKTEDIF 495

  Fly   377 -----------------LMAFIIFIANVGVISVTMVVLVEILPQKIRAVATSFCLGCLSFFAFAS 424
                             |:.:::|.| .|:..:...|..||.|...|:...:...|....|....
Human   496 WAYNFCPTPYSWTALLGLILYLVFFA-PGMGPMPWTVNSEIYPLWARSTGNACSSGINWIFNVLV 559

  Fly   425 LKTFPLMMFHLGLAATMWFCAAVSVICLFYVVVCLEETKGR------SMYD 469
            ..||.....:|......:..|..:.:.|.::..||.||||:      |::|
Human   560 SLTFLHTAEYLTYYGAFFLYAGFAAVGLLFIYGCLPETKGKKLEEIESLFD 610

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG15406	NP_608761.2	MFS_GLUT6_8_Class3_like	19..469	CDD:340916	111/566 (20%)
SLC2A13	NP_443117.3	MFS_HMIT_like	87..596	CDD:340918	105/537 (20%)