DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9663 and ABCG25

DIOPT Version :9

Sequence 1:	NP_608760.2	Gene:	CG9663 / 33541	FlyBaseID:	FBgn0031516	Length:	808	Species:	Drosophila melanogaster
Sequence 2:	NP_565030.1	Gene:	ABCG25 / 843527	AraportID:	AT1G71960	Length:	662	Species:	Arabidopsis thaliana

Alignment Length:	744	Identity:	197/744 - (26%)
Similarity:	323/744 - (43%)	Gaps:	150/744 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   101 PVSSPANQSQRSQASQHSDESRNTSSTATSGGSIFPHEQYKTIKKINIGFENIRYTTK------- 158
            |.|||       :.||...|.|:..|:     |.||         |.:.|.::.|..|
plant    14 PDSSP-------RLSQDPREPRSLLSS-----SCFP---------ITLKFVDVCYRVKIHGMSND 57

  Fly   159 -------FGVFQR--------ETKDVLMGLTGYFKSGELSAVIGPSGAGKSTLLNILSGYTTYG- 207
                   .|:.|:        |.:.:|.|:||....||..||:||||:|||||||.::| ..:|
plant    58 SCNIKKLLGLKQKPSDETRSTEERTILSGVTGMISPGEFMAVLGPSGSGKSTLLNAVAG-RLHGS 121

  Fly   208 -FTGDFRVNGNRRDLKAFKSNVAFIRQDTSLQAFLSVKEAMHFAANLKIGTHMTHSEKRERVKCI 271
             .||...:|..:...:..| ...|:.||..|...|:|:|.:.|.|.|::...:|...|....:.:
plant   122 NLTGKILINDGKITKQTLK-RTGFVAQDDLLYPHLTVRETLVFVALLRLPRSLTRDVKLRAAESV 185

  Fly   272 LEAIGMYENRHTRTGQ-----LSGGQKKRLAIALELVNNPPVLILDEPTTGLDSFTSNQLINLLK 331
            :..:|:.:..:|..|.     :|||::||::||.||:.||.:|:|||||:|||:..:.:|:..|.
plant   186 ISELGLTKCENTVVGNTFIRGISGGERKRVSIAHELLINPSLLVLDEPTSGLDATAALRLVQTLA 250

  Fly   332 KLAI-EGRTVICTIHQPSALTFAMFDHLYAIGEGKCIYAGGAQNLLPFLGALNLHCPESYNPADY 395
            .||. :|:||:.:|||||:..|.|||.:..:.||||::.|..::.:.:..::........||||:
plant   251 GLAHGKGKTVVTSIHQPSSRVFQMFDTVLLLSEGKCLFVGKGRDAMAYFESVGFSPAFPMNPADF 315

  Fly   396 LMEIATHDYDTAEDNQLEKLVALMDNGRNEDYRQSKTARVAQLAAMKKVDQLMAAGLITPVTAPV 460
            |:::|.....|              :|..|  |:....|...:.|   .|.|:         ||.
plant   316 LLDLANGVCQT--------------DGVTE--REKPNVRQTLVTA---YDTLL---------APQ 352

  Fly   461 MSTSVP-AHFMQGNTFKPLTPINELSSRVWDSQTAGIGNAGSCCKPKKKNKSRPAIELDPSHLCK 524
            :.|.:. :||.|.|.....|.:|              |...:.|
plant   353 VKTCIEVSHFPQDNARFVKTRVN--------------GGGITTC--------------------- 382

  Fly   525 RQNIYATPFYRQLSILLVRTFLLIWRDSSLTTMRFAIHLITGILIGTLYFGIG-NDAAQTLNIFR 588
                .|| ::.||.|||.| .|...|..|...:|....:...||.|.:::... .|....|.:.
plant   383 ----IAT-WFSQLCILLHR-LLKERRHESFDLLRIFQVVAASILCGLMWWHSDYRDVHDRLGLL- 440

  Fly   589 YLFYTIMFIMYCAFSGILVKFPLEFPIVSREHFNRWYSLRAYYVAITLADLPIQIICSALFIVPT 653
             .|.:|.:.:..:|:.:.. ||.|..|.:||..:..|:|.:|::|..|..|.::::..|.|:..|
plant   441 -FFISIFWGVLPSFNAVFT-FPQERAIFTRERASGMYTLSSYFMAHVLGSLSMELVLPASFLTFT 503

  Fly   654 YLMTQQPLELWRFGMFFLIVFVTALVSQSIGLAVGAA-LSLKLGSILGPFFICPFLQFSGFFLME 717
            |.|......:..|.:...::.:..|.||.:|||:||| :..|..|.:....:..|:...|:::
plant   504 YWMVYLRPGIVPFLLTLSVLLLYVLASQGLGLALGAAIMDAKKASTIVTVTMLAFVLTGGYYV-- 566

  Fly   718 KDAPVFLRWMFDISFLKYSLEGATMAIFGYDREPLACNELYCHLRHPQ-----------FILKSL 771
            ...|..:.||..:|...|.........:|...|.|  ..|.|..:..|           |:.:.:
plant   567 NKVPSGMVWMKYVSTTFYCYRLLVAIQYGSGEEIL--RMLGCDSKGKQGASAATSAGCRFVEEEV 629

  Fly   772 DMANGNYT-LALIFL--FGVLVFLRILAF 797
            ....|.:| :.::||  ||    .|:||:
plant   630 IGDVGMWTSVGVLFLMFFG----YRVLAY 654

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9663	NP_608760.2	ABCG_EPDR	145..370	CDD:213180	87/254 (34%)
		3a01204	149..808	CDD:273361	184/696 (26%)
		ABC2_membrane	540..743	CDD:279410	51/204 (25%)
ABCG25	NP_565030.1	PLN03211	1..662	CDD:215634	197/744 (26%)
		ABCG_EPDR	70..290	CDD:213180	81/221 (37%)
		ABC2_membrane	393..592	CDD:279410	51/204 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0061
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1022017at2759
OrthoFinder	1	1.000	-	-		FOG0000053
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100076
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X52
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.720