DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9663 and ABCG14

DIOPT Version :9

Sequence 1:	NP_608760.2	Gene:	CG9663 / 33541	FlyBaseID:	FBgn0031516	Length:	808	Species:	Drosophila melanogaster
Sequence 2:	NP_564383.1	Gene:	ABCG14 / 840064	AraportID:	AT1G31770	Length:	648	Species:	Arabidopsis thaliana

Alignment Length:	762	Identity:	200/762 - (26%)
Similarity:	335/762 - (43%)	Gaps:	152/762 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    76 APLAETENTVL---------STSESVYGTPLGATPVSSPANQSQRSQASQHSDESRNTSSTATSG 131
            ||..|.:..|:         :.|:||...|   |..|.|..|.
plant     7 APRPEEDGGVMVQGLPDMSDTQSKSVLAFP---TITSQPGLQM---------------------- 46

  Fly   132 GSIFPHEQYKTIKKINIGFENIRYTTK-------FGVFQRETKDVLMGLTGYFKSGELSAVIGPS 189
             |::|         |.:.||.:.|..|       .|.::.:.|.:|.|:||....||..|::|||
plant    47 -SMYP---------ITLKFEEVVYKVKIEQTSQCMGSWKSKEKTILNGITGMVCPGEFLAMLGPS 101

  Fly   190 GAGKSTLLNILSGYTTYGFTGDFRVNGNRRDLKAFKSNVAFIRQDTSLQAFLSVKEAMHFAANLK 254
            |:||:|||:.|.|..:..|:|....||.... ...|....|:.||..|...|:|.|.:.|.|.|:
plant   102 GSGKTTLLSALGGRLSKTFSGKVMYNGQPFS-GCIKRRTGFVAQDDVLYPHLTVWETLFFTALLR 165

  Fly   255 IGTHMTHSEKRERVKCILEAIGMYENRHTRT---GQL----SGGQKKRLAIALELVNNPPVLILD 312
            :.:.:|..||.|.|..::..:|:  ||.|.:   |.|    |||:|||::|..|::.||.:|:||
plant   166 LPSSLTRDEKAEHVDRVIAELGL--NRCTNSMIGGPLFRGISGGEKKRVSIGQEMLINPSLLLLD 228

  Fly   313 EPTTGLDSFTSNQLINLLKKLAIEGRTVICTIHQPSALTFAMFDHLYAIGEGKCIYAGGAQNLLP 377
            |||:||||.|:::::..:|:||..||||:.||||||:..:.|||.:..:.||..||.|.|.:.:.
plant   229 EPTSGLDSTTAHRIVTTIKRLASGGRTVVTTIHQPSSRIYHMFDKVVLLSEGSPIYYGAASSAVE 293

  Fly   378 FLGALNLHCPESYNPADYLMEIATHDYDTAEDNQLEKLVALMDNGRNEDYRQSKTARVAQLAAMK 442
            :..:|......:.||||.|:::|         |.:..     |..:....::.||.:...::|.:
plant   294 YFSSLGFSTSLTVNPADLLLDLA---------NGIPP-----DTQKETSEQEQKTVKETLVSAYE 344

  Fly   443 K-VDQLMAAGLITPVTAPVMSTSVPAHFMQGNTFKPLTPINELSSRVWDSQTAGIGNAGSCCKPK 506
            | :...:.|.|....:.....|...|              ..|.|..|
plant   345 KNISTKLKAELCNAESHSYEYTKAAA--------------KNLKSEQW----------------- 378

  Fly   507 KKNKSRPAIELDPSHLCKRQNIYATPFYRQLSILLVRTFLLIWRDSSLTTMRFAIHLITGILIGT 571
                                   .|.::.|.::||.|. :...|..|...:|....:....|.|.
plant   379 -----------------------CTTWWYQFTVLLQRG-VRERRFESFNKLRIFQVISVAFLGGL 419

  Fly   572 LYFGIGNDAAQ--TLNIFRYLFYTIMFIMYCAFSGILVKFPLEFPIVSREHFNRWYSLRAYYVAI 634
            |::.......|  |..:|   |:::.:..|..::.:.. ||.|..::.:|..:..|.|.:|::|.
plant   420 LWWHTPKSHIQDRTALLF---FFSVFWGFYPLYNAVFT-FPQEKRMLIKERSSGMYRLSSYFMAR 480

  Fly   635 TLADLPIQIICSALFIVPTYLMTQQPLELWRFGMFFLIVFVTALVSQSIGLAVGAAL-SLKLGSI 698
            .:.|||:::.....|:...|.|.....:...|.:..|:|..:.||:|.:|||.||.| ::|..:.
plant   481 NVGDLPLELALPTAFVFIIYWMGGLKPDPTTFILSLLVVLYSVLVAQGLGLAFGALLMNIKQATT 545

  Fly   699 LGPFFICPFLQFSGFFLMEKDAPVFLRWMFDISFLKYSLEGATMAIFGYDREPLACNE-LYCHLR 762
            |.......||...|:::.:  .|.|:.|:..:|:..|..: ..:.|...|.:...|:: ::|  |
plant   546 LASVTTLVFLIAGGYYVQQ--IPPFIVWLKYLSYSYYCYK-LLLGIQYTDDDYYECSKGVWC--R 605

  Fly   763 HPQF-ILKSLDMANGNYTLAL-IFLFGV-LVFLRILAFYIMSFRLRL 806
            ...| .:||:.:.|    |.: :|:.|| ||..|::| |:...|::|
plant   606 VGDFPAIKSMGLNN----LWIDVFVMGVMLVGYRLMA-YMALHRVKL 647

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9663	NP_608760.2	ABCG_EPDR	145..370	CDD:213180	92/238 (39%)
		3a01204	149..808	CDD:273361	185/680 (27%)
		ABC2_membrane	540..743	CDD:279410	50/205 (24%)
ABCG14	NP_564383.1	PLN03211	10..646	CDD:215634	197/756 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0061
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1022017at2759
OrthoFinder	1	1.000	-	-		FOG0000053
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100076
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X52
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.720