DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9663 and ABCG40

DIOPT Version :9

Sequence 1:	NP_608760.2	Gene:	CG9663 / 33541	FlyBaseID:	FBgn0031516	Length:	808	Species:	Drosophila melanogaster
Sequence 2:	NP_173005.1	Gene:	ABCG40 / 838122	AraportID:	AT1G15520	Length:	1423	Species:	Arabidopsis thaliana

Alignment Length:	854	Identity:	191/854 - (22%)
Similarity:	344/854 - (40%)	Gaps:	181/854 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 WSLASAVSPNVTGGDVIRLNH---------LKSSSE----THLPSRG---------SGTGSGALP 46
            |.....:||.:.|.:.|..|.         :::|||    |.|.|||         .|||:
plant   697 WIWGYWISPIMYGQNAILANEFFGHSWSRAVENSSETLGVTFLKSRGFLPHAYWYWIGTGA---- 757

  Fly    47 RPTTPVPSKKLSSKRPPHLTLNIKAKSHDAPLAETENTVLSTSESVYGTPLGATPVSSPAN-QSQ 110
                              |...:...:....||.|....|...::|    :...|.|.... ||.
plant   758 ------------------LLGFVVLFNFGFTLALTFLNSLGKPQAV----IAEEPASDETELQSA 800

  Fly   111 RSQASQHSDESRNTSSTATSGGSIFPHEQYKTIKKINIGFENIRYTTKF--GVFQRETKD----V 169
            ||:....:..::..       |.:.|.|.:      :|.|:|:.|:...  .:.::.|::    :
plant   801 RSEGVVEAGANKKR-------GMVLPFEPH------SITFDNVVYSVDMPQEMIEQGTQEDRLVL 852

  Fly   170 LMGLTGYFKSGELSAVIGPSGAGKSTLLNILSGYTTYGF-TGDFRVNGNRRDLKAFKSNVAFIRQ 233
            |.|:.|.|:.|.|:|::|.|||||:||:::|:|..|.|: .|:..::|..::.:.|.....:..|
plant   853 LKGVNGAFRPGVLTALMGVSGAGKTTLMDVLAGRKTGGYIDGNITISGYPKNQQTFARISGYCEQ 917

  Fly   234 DTSLQAFLSVKEAMHFAANLKIGTHMTHSEKRERVKCILEAIGMYENRHTRTG-----QLSGGQK 293
            .......::|.|::.::|.|::...:..::::..::.::|.:.:...|....|     .||..|:
plant   918 TDIHSPHVTVYESLVYSAWLRLPKEVDKNKRKIFIEEVMELVELTPLRQALVGLPGESGLSTEQR 982

  Fly   294 KRLAIALELVNNPPVLILDEPTTGLDSFTSNQLINLLKKLAIEGRTVICTIHQPSALTFAMFDHL 358
            |||.||:|||.||.::.:||||:|||:..:..::..::.....||||:|||||||...|..||.|
plant   983 KRLTIAVELVANPSIIFMDEPTSGLDARAAAIVMRTVRNTVDTGRTVVCTIHQPSIDIFEAFDEL 1047

  Fly   359 YAIGE-GKCIYAG--GAQ-----NLLPFLGALNLHCPESYNPADYLMEIATHDYDTA---EDNQL 412
            :.:.. |:.||.|  |.:     |....:..:| ...|.||||.:::|::|...:.|   :..|:
plant  1048 FLLKRGGEEIYVGPLGHESTHLINYFESIQGIN-KITEGYNPATWMLEVSTTSQEAALGVDFAQV 1111

  Fly   413 EKLVALMDNGRNEDYRQSKTARVAQLAAMKKVDQLMAAGLITPVTAPVMSTSVPAHFMQGNTFKP 477
            .|        .:|.|:::|..
plant  1112 YK--------NSELYKRNKEL-------------------------------------------- 1124

  Fly   478 LTPINELSSRVWDSQTAGIGNAGSCCKPKKKNKSRPAIELDPSHLCKRQNIYATPFYRQLSILLV 542
               |.||      ||.|          |..|:...|             ..|:..|..|....|.
plant  1125 ---IKEL------SQPA----------PGSKDLYFP-------------TQYSQSFLTQCMASLW 1157

  Fly   543 RTFLLIWRDSSLTTMRFAIHLITGILIGTLYFGIG--NDAAQTL-NIFRYLFYTIMFIMYCAFSG 604
            :.....||:...|.:||...:...::.||:::.:|  ....|.| |....::..::|:.....:.
plant  1158 KQHWSYWRNPPYTAVRFLFTIGIALMFGTMFWDLGGKTKTRQDLSNAMGSMYTAVLFLGLQNAAS 1222

  Fly   605 ILVKFPLEFPIVSREHFNRWYSLRAYYVAITLADLPIQIICSALFIVPTYLMTQQPLELWRFGMF 669
            :.....:|..:..||.....||...|..|....::|..::.:.::.:..|.|........:|..:
plant  1223 VQPVVNVERTVFYREQAAGMYSAMPYAFAQVFIEIPYVLVQAIVYGLIVYAMIGFEWTAVKFFWY 1287

  Fly   670 FLIVFVTALVSQSIG-LAVGAALSLKLGSILGPFFICPFLQFSGFFLMEKDAPVFLRWMFDISFL 733
            ...::.:.|.....| :||....:..:.|::...|...:..||||.:.....||:..|.:.:..:
plant  1288 LFFMYGSFLTFTFYGMMAVAMTPNHHIASVVSSAFYGIWNLFSGFLIPRPSMPVWWEWYYWLCPV 1352

  Fly   734 KYSLEGATMAIFGYDREPLACNELYCHLRHPQFILKSLDMANG--NYTLALIFLFGVLVFLRILA 796
            .::|.|...:.||...||:|.:    ::...|||.:......|  ....|:..:| .|:|..|.|
plant  1353 AWTLYGLIASQFGDITEPMADS----NMSVKQFIREFYGYREGFLGVVAAMNVIF-PLLFAVIFA 1412

  Fly   797 FYIMSFRLR 805
            ..|.||..:
plant  1413 IGIKSFNFQ 1421

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9663	NP_608760.2	ABCG_EPDR	145..370	CDD:213180	73/237 (31%)
		3a01204	149..808	CDD:273361	158/686 (23%)
		ABC2_membrane	540..743	CDD:279410	39/206 (19%)
ABCG40	NP_173005.1	PLN03140	10..1423	CDD:215599	191/854 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X52
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.910