DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9663 and ABCG35

DIOPT Version :9

Sequence 1:	NP_608760.2	Gene:	CG9663 / 33541	FlyBaseID:	FBgn0031516	Length:	808	Species:	Drosophila melanogaster
Sequence 2:	NP_172973.1	Gene:	ABCG35 / 838087	AraportID:	AT1G15210	Length:	1442	Species:	Arabidopsis thaliana

Alignment Length:	692	Identity:	167/692 - (24%)
Similarity:	283/692 - (40%)	Gaps:	126/692 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    93 YGTPLGATPVSSPANQSQRSQASQHSDESRNTSSTATSGGSIFPHEQYKTIKKINIGFENIRYTT 157
            |..|||......|..:.:.::....|::.....|.:...|.:.|      ...:.:.|::::|..
plant   791 YLDPLGKAQAILPKEEDEEAKGKAGSNKETEMESVSAKKGMVLP------FTPLAMSFDDVKYFV 849

  Fly   158 KFGVFQR-----ETK-DVLMGLTGYFKSGELSAVIGPSGAGKSTLLNILSGYTTYGF-TGDFRVN 215
            ......|     ||: .:|.|:|..|:.|.|:|::|.|||||:||:::|:|..|.|: .||.||:
plant   850 DMPAEMREQGVQETRLQLLKGVTSAFRPGVLTALMGVSGAGKTTLMDVLAGRKTGGYIEGDVRVS 914

  Fly   216 GNRRDLKAFKSNVAFIRQDTSLQAFLSVKEAMHFAANLKIGTHMTHSEKRERVKCILEAIGMYEN 280
            |..:..:.|.....:..|.......::|:|::.|:|.|::...::..:|...|..::|.:.:.:.
plant   915 GFPKKQETFARISGYCEQTDIHSPQVTVRESLIFSAFLRLAKEVSKEDKLMFVDQVMELVELVDL 979

  Fly   281 RHTRTG-----QLSGGQKKRLAIALELVNNPPVLILDEPTTGLDSFTSNQLINLLKKLAIEGRTV 340
            |....|     .||..|:|||.||:|||.||.::.:||||:|||:..:..::..::.....||||
plant   980 RDAIVGLPGVTGLSTEQRKRLTIAVELVANPSIIFMDEPTSGLDARAAAIVMRAVRNTVDTGRTV 1044

  Fly   341 ICTIHQPSALTFAMFDHLYAIGE-GKCIYAGGAQNLLPFLGALNLH--------------CPESY 390
            :|||||||...|..||.|..:.. |..||:|.       ||. |.|              .||.|
plant  1045 VCTIHQPSIDIFEAFDELLLMKRGGHVIYSGP-------LGR-NSHKVVEYFESFPGVPKIPEKY 1101

  Fly   391 NPADYLMEIATHDYDTAEDNQLEKLVALMDNGRNEDYRQSKTARVAQLAAMKKVDQLMAAGLITP 455
            |||.:::|.::             |.|.:..|             ...|.:.|     |:.|...
plant  1102 NPATWMLEASS-------------LAAELKLG-------------VDFAELYK-----ASALCQR 1135

  Fly   456 VTAPVMSTSVPAHFMQGNTFKPLTPINELSSRVWDSQTAGIGNAGSCCKPKKKNKSRPAIELDPS 520
            ..|.|...|||.   ||.|  .|....:.|...|       |...||
plant  1136 NKALVQELSVPP---QGAT--DLYFATQFSQNTW-------GQFKSC------------------ 1170

  Fly   521 HLCKRQNIYATPFYRQLSILLVRTFLLIWRDSSLTTMRFAIHLITGILIGTLYFGIGNDAAQTLN 585
                                |.:.:...||......:||...|.|.::||::::.||...:...:
plant  1171 --------------------LWKQWWTYWRSPDYNLVRFIFTLATSLMIGSVFWQIGGKRSNVQD 1215

  Fly   586 ---IFRYLFYTIMFIMYCAFSGILVKFPLEFPIVSREHFNRWYSLRAYYVAITLADLPIQIICSA 647
               :...::..::|:.....|.:.....:|..:..||.....||...|.::....:||..:|.:.
plant  1216 LTMVIGAIYAAVVFVGINNCSTVQPMVAVERTVFYREKAAGMYSAIPYAISQVTCELPYVLIQTT 1280

  Fly   648 LFIVPTYLMTQQPLELWRFGMFFLIVFVTALVSQSIG-LAVGAALSLKLGSILGPFFICPFLQFS 711
            .:.:..|.|.....:..:|..|..|.:.:.|.....| :.|....:.::.||....|...|..||
plant  1281 YYSLIIYSMVGFEWKASKFLWFIFINYFSFLYWTYYGMMTVSLTPNQQVASIFASAFYGIFNLFS 1345

  Fly   712 GFFLMEKDAPVFLRWMFDISFLKYSLEGATMAIFGYDREPLA 753
            |||:.....|.:..|.:.|..:.:::.|...:.:|....|:|
plant  1346 GFFIPRPKIPKWWVWYYWICPVAWTIYGLITSQYGDVETPIA 1387

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9663	NP_608760.2	ABCG_EPDR	145..370	CDD:213180	79/237 (33%)
		3a01204	149..808	CDD:273361	158/636 (25%)
		ABC2_membrane	540..743	CDD:279410	43/206 (21%)
ABCG35	NP_172973.1	PLN03140	8..1442	CDD:215599	167/692 (24%)
		ABC_trans_N	88..163	CDD:291196
		ABCG_PDR_domain1	182..424	CDD:213200
		ABC2_membrane	525..731	CDD:279410
		PDR_assoc	738..802	CDD:285559	4/10 (40%)
		ABCG_PDR_domain2	837..1075	CDD:213199	79/237 (33%)
		ABC2_membrane	1170..1375	CDD:279410	44/242 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X52
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.910