DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9663 and ABCG28

DIOPT Version :9

Sequence 1:	NP_608760.2	Gene:	CG9663 / 33541	FlyBaseID:	FBgn0031516	Length:	808	Species:	Drosophila melanogaster
Sequence 2:	NP_200882.4	Gene:	ABCG28 / 836195	AraportID:	AT5G60740	Length:	1109	Species:	Arabidopsis thaliana

Alignment Length:	750	Identity:	176/750 - (23%)
Similarity:	298/750 - (39%)	Gaps:	183/750 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 DVIR-LNHLKSSSETHLPSRGSGTGSGALPRPTTPVPSKKLSS---------KRPPHLTLNI--- 69
            |::| |:..|..|:..||..   .||.:..:........||:.         :.|....|.|
plant   377 DLMRGLSQAKPGSDAALPPM---LGSSSDTKKGKKKEKNKLTEMLHDIEQNPEDPEGFNLEIGDK 438

  Fly    70 KAKSHDAPLAETENTVLSTSESVYGTPLGATPVSSPANQSQRSQASQHSDESRNTSSTATSGGSI 134
            ..|.| ||..:..:|........||             |.::.:|.|..:::...|...:....|
plant   439 NIKKH-APKGKALHTQSQMFRYAYG-------------QIEKEKAMQEQNKNLTFSGVISMANDI 489

  Fly   135 FPHEQYKTIKK---INIGFENIRYTTKFGVFQRETKDVLMGLTGYFKSGELSAVIGPSGAGKSTL 196
                   .|:|   |.:.|:::..|.|     .:.|.::..:||....|.:|||:|||||||:|.
plant   490 -------DIRKRPMIEVAFKDLSITLK-----GKNKHLMRCVTGKLSPGRVSAVMGPSGAGKTTF 542

  Fly   197 LNILSGYTTYG--FTGDFRVNGNRRDLKAFKSNVAFIRQDTSLQAFLSVKEAMHFAANLKIGTHM 259
            |..|:|... |  .||...|||....::::|..:.|:.||..:...|:|:|.:.|:|..::...:
plant   543 LTALTGKAP-GCIMTGMILVNGKVESIQSYKKIIGFVPQDDIVHGNLTVEENLWFSARCRLPADL 606

  Fly   260 THSEKRERVKCILEAIGMYENRHTRTGQ-----LSGGQKKRLAIALELVNNPPVLILDEPTTGLD 319
            ...||...|:.::|::|:...|.:..|.     :||||:||:.:.||:|..|.:|||||||:|||
plant   607 PKPEKVLVVERVIESLGLQHVRDSLVGTVEKRGISGGQRKRVNVGLEMVMEPSLLILDEPTSGLD 671

  Fly   320 SFTSNQLINLLKKLAIEGRTVICTIHQPSALTFAMFDHLYAIGEGKCI-YAGGAQNLLPFLGALN 383
            |.:|..|:..|::.|:||..:...:||||...|.|||.|..:.:|..| |.|..:.:..:..:|.
plant   672 SSSSQLLLRALRREALEGVNICMVVHQPSYTLFRMFDDLILLAKGGLICYQGPVKKVEEYFSSLG 736

  Fly   384 LHCPESYNPADYLMEIATHDYDTAEDNQLEKLVALMDNGRNEDYRQSKTARVAQLAAMKKVDQLM 448
            :..||..||.||.::|            ||
plant   737 IVVPERVNPPDYYIDI------------LE----------------------------------- 754

  Fly   449 AAGLITPVTAP-VMSTSVPAHFMQGNTFK-PLTPINEL----SSRVWDSQTAG-------IGNAG 500
              |::.|.|:. |....:|..:|..|.:. |:..:..:    ||...::...|       :|:.|
plant   755 --GILKPSTSSGVTYKQLPVRWMLHNGYPVPMDMLKSIEGMASSASGENSAHGGSAHGSVVGDDG 817

  Fly   501 SCCKPKKKNKSRPAIELDPSHLCKRQNIYATP----------FYRQLSILLVRTFLLIWRDSSLT 555
            :....:.....:..:|:...:|   ||.:::.          .|:|....|.|......|::...
plant   818 TSFAGEFWQDVKANVEIKKDNL---QNNFSSSGDLSEREVPGVYQQYRYFLGRLGKQRLREARTL 879

  Fly   556 TMRFAIHLITGILIGTLYFGIGNDAAQTLNIFRYLFYTIMFIMYCAFSGILVKFPLEFPIVSREH 620
            .:.:.|.|:.||.:|||    ...:.:|.....|.:..|...:.|..:. |..|.|:     :.|
plant   880 AVDYLILLLAGICLGTL----AKVSDETFGAMGYTYTVIAVSLLCKITA-LRSFSLD-----KLH 934

  Fly   621 FNRWYSLR------AYYVA---------------------------ITLADLPIQIIC-----SA 647
            :  |...|      ||::|                           .|:.|..:.:||     :.
plant   935 Y--WRESRAGMSSLAYFLAKDTVDHFNTIVKPLVYLSMFYFFNNPRSTVTDNYVVLICLVYCVTG 997

  Fly   648 LFIVPTYLMTQQPLELWRFGMFFLIVFVTALVSQS 682
            :......|....|.:||.    .|:..|..|::.|
plant   998 IAYTLAILFEPGPAQLWS----VLLPVVLTLIATS 1028

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9663	NP_608760.2	ABCG_EPDR	145..370	CDD:213180	84/235 (36%)
		3a01204	149..808	CDD:273361	146/602 (24%)
		ABC2_membrane	540..743	CDD:279410	34/180 (19%)
ABCG28	NP_200882.4	ABCG_EPDR	496..723	CDD:213180	83/232 (36%)
ABCG28	NP_200882.4	3a01204	513..1103	CDD:273361	143/584 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	121	1.000	Domainoid score	I1855
eggNOG	1	0.900	-	-		E2759_KOG0061
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1022017at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.820