DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9663 and ABCG23

DIOPT Version :9

Sequence 1:	NP_608760.2	Gene:	CG9663 / 33541	FlyBaseID:	FBgn0031516	Length:	808	Species:	Drosophila melanogaster
Sequence 2:	NP_197442.2	Gene:	ABCG23 / 832061	AraportID:	AT5G19410	Length:	633	Species:	Arabidopsis thaliana

Alignment Length:	737	Identity:	181/737 - (24%)
Similarity:	311/737 - (42%)	Gaps:	178/737 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   112 SQASQHSDE-------SRNTSSTATSGGSIFPHEQYKTIKKINIGFENIRYTTKFGVFQRETKDV 169
            :.|:.|.:|       :.|:....:|..|.|......|..:.::...|:.||...       ..:
plant    18 AMATSHREEDSIILFSASNSPDEFSSASSSFSSSPLPTPNRYSLTVTNLSYTINH-------TPI 75

  Fly   170 LMGLTGYFKSGELSAVIGPSGAGKSTLLNILSGYTTYGFTGDFRVN------------GNRR--D 220
            |..::...:|.::.||:||||.||||||.|:||          |||            .||:  |
plant    76 LNSVSLAAESSKILAVVGPSGTGKSTLLKIISG----------RVNHKALDPSSAVLMNNRKITD 130

  Fly   221 LKAFKSNVAFIRQDTSLQAFLSVKEAMHFAANLKIGTHMTHSEKRERVKCILEAIGMYENRHTRT 285
            ....:....|:.||..|...|:|||.:.::|...: ...|..|:.|||:.:|..:|:...:.:..
plant   131 YNQLRRLCGFVPQDDDLLPLLTVKETLMYSAKFSL-RDSTAKEREERVESLLSDLGLVLVQDSFV 194

  Fly   286 GQ-------LSGGQKKRLAIALELVNNPPVLILDEPTTGLDSFTSNQLINLLKKLA-IEGRTVIC 342
            |:       :|||::||::||:|::.:||:|:|||||:||||..|.|::.||..:| .:.|||:.
plant   195 GEGDEEDRGVSGGERKRVSIAVEMIRDPPILLLDEPTSGLDSRNSLQVVELLATMAKSKQRTVLF 259

  Fly   343 TIHQPSALTFAMFDHL--YAI-GEGKCIYAGGAQNLLPFLGALNLHCPESYNPADYLMEIATHDY 404
            :|||||   :.:.|::  |.| ..|..|:.|..::|...:..|....||..||.::.|||
plant   260 SIHQPS---YRILDYISDYLILSRGSVIHLGSLEHLEDSIAKLGFQIPEQLNPIEFAMEI----- 316

  Fly   405 DTAEDNQLEKLVALMDNGRNEDYRQSKTARVAQLAAMKKVDQLMAAGLITPVTAPVMSTSVPAHF 469
                                                   |:.|
plant   317 ---------------------------------------VESL---------------------- 320

  Fly   470 MQGNTFKPLTPINELSSRVW--DSQTAGIGNAGSCCKPKKKNKSRPAIELDPSHLCKRQNIYATP 532
               .||||.:.....||.:|  :::..||        ..||...|.....:.|:||.|   :...
plant   321 ---RTFKPNSVAVVESSSMWPENNENDGI--------ISKKEAFRVLDVTEISYLCSR---FCKI 371

  Fly   533 FYRQLSILLVRTFLLIWRDSSLTTMRFAIHLITGILIGTLYFGIGND---AAQTLNIFRYLFYTI 594
            .||...:.|.||...:               :.|:.:|::|..:..|   .|:.|.:|.   :::
plant   372 IYRTKQLFLARTMQAV---------------VAGLGLGSVYTRLKRDEEGVAERLGLFA---FSL 418

  Fly   595 MFIMYCAFSGILVKFPL---EFPIVSREHFNRWYSLRAYYVAITLADLPIQIICSALFIVPTYLM 656
            .|::    |..:...|:   |..::.:|.....|.:.:|.:|.|:|.:|...:.|.||.:|.|.:
plant   419 SFLL----SSTVEALPIYLRERRVLMKESSRGSYRISSYMIANTIAFVPFLFVVSLLFSIPVYWI 479

  Fly   657 TQQPLELWRFGMFFLIVFVTALVSQSIGLAVGAAL-------SLKLGSILGPFFICPFLQFSGFF 714
            ......:..|..|.|.|::..|::.|:.|.:.|..       || :.::||.||:     |||:|
plant   480 VGLNPSIQAFSFFVLCVWLIILMASSLVLFLSAVSPDFISGNSL-ICTVLGAFFL-----FSGYF 538

  Fly   715 LMEKDAPVFLRWMFDISFLKYSLEGATMAIFGYDREP-LACNELYCHLRHPQFILKSLDMANGNY 778
            :.::..|....:|:.:|..:|.||...:..:...||. .:...:.| |...:.:||...:.....
plant   539 IPKEKIPKPWMFMYYVSLYRYPLESMVVNEYWSMREECFSSGNMGC-LMTGEDVLKERGLDKDTR 602

  Fly   779 TLALIFLFGVLVFLRILAFYIM 800
            .:.:..:....||.|||.:.|:
plant   603 WINVGIMLAFFVFYRILCWGIL 624

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9663	NP_608760.2	ABCG_EPDR	145..370	CDD:213180	81/249 (33%)
		3a01204	149..808	CDD:273361	173/693 (25%)
		ABC2_membrane	540..743	CDD:279410	50/215 (23%)
ABCG23	NP_197442.2	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0061
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1022017at2759
OrthoFinder	1	1.000	-	-		FOG0000053
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR48041
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.920