DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9663 and ABCG22

DIOPT Version :9

Sequence 1:	NP_608760.2	Gene:	CG9663 / 33541	FlyBaseID:	FBgn0031516	Length:	808	Species:	Drosophila melanogaster
Sequence 2:	NP_568169.1	Gene:	ABCG22 / 830541	AraportID:	AT5G06530	Length:	751	Species:	Arabidopsis thaliana

Alignment Length:	827	Identity:	210/827 - (25%)
Similarity:	367/827 - (44%)	Gaps:	155/827 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 AVSPNVTGGDVIRLNHLKSSSETHL----PSRGSGTGSGALPRPTTPVPSKKLSSKRPPHLTLNI 69
            |.:|...||.    ..|...|...|    |.|.||.|:             .:...|...|.|.:
plant    42 ATAPAAVGGG----GTLSRKSSRRLMGMSPGRSSGAGT-------------HIRKSRSAQLKLEL 89

  Fly    70 KAKSHDAPLAETENTVLSTSESVYGTPLGATPVSSPANQSQRSQASQHSDESRNTSSTATSGGSI 134
            :..|..|.|:...:..|..|.|..|..:....:         |.:...||:......  ...|..
plant    90 EEVSSGAALSRASSASLGLSFSFTGFAMPPEEI---------SDSKPFSDDEMIPED--IEAGKK 143

  Fly   135 FPHEQYKTIKKINIGFENIRYTTKFGVFQRET----KDVLMGLTGYFKSGELSAVIGPSGAGKST 195
            .|..|.:....|.:.|.::.|..   |.::.|    |::|.|::|....||:.|::||||:||:|
plant   144 KPKFQAEPTLPIFLKFRDVTYKV---VIKKLTSSVEKEILTGISGSVNPGEVLALMGPSGSGKTT 205

  Fly   196 LLNILSGYTTYGFTGDFRVNGNRRDLKAFKSNVAFIRQDTSLQAFLSVKEAMHFAANLKIGTHMT 260
            ||::|:|..:...||......::...|..||.:.|:.||..|...|:|||.:.:||.|::...:|
plant   206 LLSLLAGRISQSSTGGSVTYNDKPYSKYLKSKIGFVTQDDVLFPHLTVKETLTYAARLRLPKTLT 270

  Fly   261 HSEKRERVKCILEAIGMYENRHTRTG-----QLSGGQKKRLAIALELVNNPPVLILDEPTTGLDS 320
            ..:|::|...:::.:|:...:.|..|     .:|||::||::|..|::.||.:|:|||||:||||
plant   271 REQKKQRALDVIQELGLERCQDTMIGGAFVRGVSGGERKRVSIGNEIIINPSLLLLDEPTSGLDS 335

  Fly   321 FTSNQLINLLKKLAIEGRTVICTIHQPSALTFAMFDHLYAIGEGKCIYAGGAQNLLPFLGALNLH 385
            .|:.:.|.:|..:|..|:|||.||||||:..|..||.|..:|.|..:|.|.:...|.:..::...
plant   336 TTALRTILMLHDIAEAGKTVITTIHQPSSRLFHRFDKLILLGRGSLLYFGKSSEALDYFSSIGCS 400

  Fly   386 CPESYNPADYLMEIATHDY-DTAEDNQLEKLVALMDNGRNEDYRQSKTARVAQLAAMKKVDQLMA 449
            ...:.|||::|:::|..:. |.:..::|:..|.:.::|     |:::|.:.:..|
plant   401 PLIAMNPAEFLLDLANGNINDISVPSELDDRVQVGNSG-----RETQTGKPSPAA---------- 450

  Fly   450 AGLITPVTAPVMSTSVPAHFMQGNTFKPLTPINELSSRVWDSQTAGIGNAGSCCKPKKKNKSRPA 514
                                           ::|.....::::.|          .::|.|....
plant   451 -------------------------------VHEYLVEAYETRVA----------EQEKKKLLDP 474

  Fly   515 IELD-----PSHLCKRQNIYATPFYRQLSILLVRTFLLIWRDSSLTTMRFAIHLITGILIGTLYF 574
            :.||     .|...|||  :.|.::.|..||..|. |...|....:.:|....|.|.:::|.|::
plant   475 VPLDEEAKAKSTRLKRQ--WGTCWWEQYCILFCRG-LKERRHEYFSWLRVTQVLSTAVILGLLWW 536

  Fly   575 --------GIGNDAAQTLNIFRYLFYTIMFIMYCAFSGILVKFPLEFPIVSREHFNRWYSLRAYY 631
                    |:.:.|.       .||:..:|..:......:..||.|..::::|.....|.|.||:
plant   537 QSDIRTPMGLQDQAG-------LLFFIAVFWGFFPVFTAIFAFPQERAMLNKERAADMYRLSAYF 594

  Fly   632 VAITLADLPIQIICSALFIVPTYLMTQQPLELWRFGMFFLIVFVTALVSQSIGLAVGAAL-SLKL 695
            :|.|.:|||:..|..:||::..|.||...:..:.|.:..|.||:..:.:|.:|||:||.| .||.
plant   595 LARTTSDLPLDFILPSLFLLVVYFMTGLRISPYPFFLSMLTVFLCIIAAQGLGLAIGAILMDLKK 659

  Fly   696 GSILGPFFICPFLQFSGFFLMEKDAPVFLRWMFDISFLKYSLEGATMAIFGYDREPLACNELYCH 760
            .:.|....:..|:...|||:  |..|||:.|:..:||..::.                  :|...
plant   660 ATTLASVTVMTFMLAGGFFV--KKVPVFISWIRYLSFNYHTY------------------KLLLK 704

  Fly   761 LRHPQFI--LKSLDMANGNYTLA--LIFLFGVLVFLRILAFYIMSFR 803
            :::..|.  :..:.:.||...:|  ::.:||    .|:||:  :|.|
plant   705 VQYQDFAVSINGMRIDNGLTEVAALVVMIFG----YRLLAY--LSLR 745

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9663	NP_608760.2	ABCG_EPDR	145..370	CDD:213180	85/233 (36%)
		3a01204	149..808	CDD:273361	181/683 (27%)
		ABC2_membrane	540..743	CDD:279410	58/211 (27%)
ABCG22	NP_568169.1	PLN03211	112..748	CDD:215634	189/740 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0061
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1022017at2759
OrthoFinder	1	1.000	-	-		FOG0000053
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100076
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X52
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.720