DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9663 and ABCG27

DIOPT Version :9

Sequence 1:	NP_608760.2	Gene:	CG9663 / 33541	FlyBaseID:	FBgn0031516	Length:	808	Species:	Drosophila melanogaster
Sequence 2:	NP_001319729.1	Gene:	ABCG27 / 824396	AraportID:	AT3G52310	Length:	743	Species:	Arabidopsis thaliana

Alignment Length:	748	Identity:	211/748 - (28%)
Similarity:	331/748 - (44%)	Gaps:	127/748 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 LKSSSETHLPSRGSGTGSGALPRP-TTPVPSKKLSSKR--PPHLTLNIKAKS-HDA-PLAE-TEN 83
            |||||.......||..||....|. |...||...:||.  ..|:.   |||| |.| .||. |..
plant    24 LKSSSLDFSNGDGSSHGSKQHVRARTLSSPSYSSNSKNRWNTHIR---KAKSAHPALDLAGLTGG 85

  Fly    84 TVLSTSESV-YGTPLGATPVSSPANQSQRSQASQHSD-----ESRNTSSTATSGGSIFPHEQYKT 142
            ..||.:.|. .|.....|..:.|..:...|:...:.|     |:..:|.........||
plant    86 AALSRASSASLGLSFSFTGFTVPHEEIIASERCSNDDILEDIEAATSSVVKFQAEPTFP------ 144

  Fly   143 IKKINIGFENIRY--TTKFGVFQRETKDVLMGLTGYFKSGELSAVIGPSGAGKSTLLNILSG-YT 204
               |.:.|.:|.|  ||| |:.....|.:|.|::|....|||.|::||||:||:||||.|.| :.
plant   145 ---IYLKFIDITYKVTTK-GMTSSSEKSILNGISGSAYPGELLALMGPSGSGKTTLLNALGGRFN 205

  Fly   205 TYGFTGDFRVNGNRRDLKAFKSNVAFIRQDTSLQAFLSVKEAMHFAANLKIGTHMTHSEKRERVK 269
            .....|....| ::...|..|:.:.|:.||..|...|:|||.:.:.|.|::...:|..||.:|..
plant   206 QQNIGGSVSYN-DKPYSKHLKTRIGFVTQDDVLFPHLTVKETLTYTALLRLPKTLTEQEKEQRAA 269

  Fly   270 CILEAIGMYENRHTRTG-----QLSGGQKKRLAIALELVNNPPVLILDEPTTGLDSFTSNQLINL 329
            .:::.:|:...:.|..|     .:|||::||:.|..|::.||.:|:|||||:.|||.|:.:::.:
plant   270 SVIQELGLERCQDTMIGGSFVRGVSGGERKRVCIGNEIMTNPSLLLLDEPTSSLDSTTALKIVQM 334

  Fly   330 LKKLAIEGRTVICTIHQPSALTFAMFDHLYAIGEGKCIYAGGAQNLLPFLGALNLHCPESYNPAD 394
            |..:|..|:|::.||||||:..|..||.|..:..|..:|.|.|...:.:..::......:.|||:
plant   335 LHCIAKAGKTIVTTIHQPSSRLFHRFDKLVVLSRGSLLYFGKASEAMSYFSSIGCSPLLAMNPAE 399

  Fly   395 YLMEIATHDYDTAEDNQLEKLVALMDNGRNE----------DYRQSKTARVAQLAAMKKVDQLMA 449
            :|:::...:.:........|....|.|..:|          .|...:.|...|:|.|:|: :|||
plant   400 FLLDLVNGNMNDISVPSALKEKMKMXNSCSEIGSSKPAPTVVYEYLEEAYKTQIAVMEKM-KLMA 463

  Fly   450 AGLITPV----TAPVMSTSVPAHFMQGNTFKPLTPINELSSRVWDSQTAGIGNAGSCCKPKKKNK 510
                 ||    ...:|.|               .|..|.....|:..         |....:..|
plant   464 -----PVPLDEEVKLMIT---------------CPKREWGLSWWEQY---------CLLSLRGIK 499

  Fly   511 SRPAIELDPSHLCKRQNIYATPFYRQLSILLVRTFL-LIWRDSSLTTMRFAIHLITGI--LIGTL 572
            .|            |.:.::  :.|...:|.....| |:|..|.:|:.:       |:  .:|.|
plant   500 ER------------RHDYFS--WLRVTQVLSTAIILGLLWWQSDITSXK-------GLQDQVGLL 543

  Fly   573 YFGIGNDAAQTLNIFRYLF--YTIMFIMYCAFSGILVKFPLEFPIVSREHFNRWYSLRAYYVAIT 635
            :|         :.:|...|  :|.:|           .||.|..::|:|..:..|.|.||:||.|
plant   544 FF---------IAVFWGFFPVFTAIF-----------TFPQERAMLSKERESNMYRLSAYFVART 588

  Fly   636 LADLPIQIICSALFIVPTYLMTQQPLELWRFGMFFLIVFVTALVSQSIGLAVGAAL-SLKLGSIL 699
            .:|||:.:|...||:|..|.|....|....|.:..|.||:..:.:|.:|||:||:| .||..:.|
plant   589 TSDLPLDLILPVLFLVVVYFMAGLRLRAESFFLSVLTVFLCIVAAQGLGLAIGASLMDLKKATTL 653

  Fly   700 GPFFICPFLQFSGFFLMEKDAPVFLRWMFDISF 732
            ....:..|:...|:|:  |..|.|:.|:..:||
plant   654 ASVTVMTFMLAGGYFV--KKVPFFIAWIRFMSF 684

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9663	NP_608760.2	ABCG_EPDR	145..370	CDD:213180	84/232 (36%)
		3a01204	149..808	CDD:273361	173/612 (28%)
		ABC2_membrane	540..743	CDD:279410	59/199 (30%)
ABCG27	NP_001319729.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0061
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1022017at2759
OrthoFinder	1	1.000	-	-		FOG0000053
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100076
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X52
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.720