DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9663 and ABCG21

DIOPT Version :9

Sequence 1:	NP_608760.2	Gene:	CG9663 / 33541	FlyBaseID:	FBgn0031516	Length:	808	Species:	Drosophila melanogaster
Sequence 2:	NP_001189973.1	Gene:	ABCG21 / 822149	AraportID:	AT3G25620	Length:	672	Species:	Arabidopsis thaliana

Alignment Length:	790	Identity:	211/790 - (26%)
Similarity:	357/790 - (45%)	Gaps:	186/790 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    49 TTPVPSKKLSSKRPPHLTLNIKAKSHDAPLAETENTVLSTSESVYGTPLGATPVSSPANQSQRSQ 113
            |:||...:.||            .||..|..:.:|                 ....|::||::|.
plant    22 TSPVQENRFSS------------PSHVNPCLDDDN-----------------DHDGPSHQSRQSS 57

  Fly   114 ASQHSDESRNTSSTATSGGSIFPHEQYKTIKKINIGFENIRYTTK---------FGVFQRETKD- 168
            ..:.|                        ::.|.:.||.:.|:.|         ||  .:|.|.
plant    58 VLRQS------------------------LRPIILKFEELTYSIKSQTGKGSYWFG--SQEPKPN 96

  Fly   169 --VLMGLTGYFKSGELSAVIGPSGAGKSTLLNILSGYTTYGFTGDFRVNGNRRDLKAFKSNV--- 228
              ||..::|..|.|||.|::||||:||:||:..|:|......:|....||     :.|.|:|
plant    97 RLVLKCVSGIVKPGELLAMLGPSGSGKTTLVTALAGRLQGKLSGTVSYNG-----EPFTSSVKRK 156

  Fly   229 -AFIRQDTSLQAFLSVKEAMHFAANLKIGTHMTHSEKRERVKCILEAIGMYENRHTRTG-----Q 287
             .|:.||..|...|:|.|.:.:.|.|::...:|..||.|:|:.::..:|:....::..|     .
plant   157 TGFVTQDDVLYPHLTVMETLTYTALLRLPKELTRKEKLEQVEMVVSDLGLTRCCNSVIGGGLIRG 221

  Fly   288 LSGGQKKRLAIALELVNNPPVLILDEPTTGLDSFTSNQLINLLKKLAIEGRTVICTIHQPSALTF 352
            :|||::||::|..|::.||.:|:|||||:||||.|:.:::..|:.||..||||:.||||||:..:
plant   222 ISGGERKRVSIGQEMLVNPSLLLLDEPTSGLDSTTAARIVATLRSLARGGRTVVTTIHQPSSRLY 286

  Fly   353 AMFDHLYAIGEGKCIYAGGAQNLLPFLGALNLHCPESY-NPADYLMEIATH-DYDTAEDNQLEKL 415
            .|||.:..:.||..||:|.:..::.:.|::......|: ||||:::::|.. ..||.:.:|:|
plant   287 RMFDKVLVLSEGCPIYSGDSGRVMEYFGSIGYQPGSSFVNPADFVLDLANGITSDTKQYDQIE-- 349

  Fly   416 VALMDNGRNEDYRQSKTARVAQLAAMKKVDQLMAAGLITPVTAPVMSTSVPAHFMQGNTFKPLTP 480
                .|||.:...:..:.:.:.:::.||                             |.:.||.
plant   350 ----TNGRLDRLEEQNSVKQSLISSYKK-----------------------------NLYPPLK- 380

  Fly   481 INELSSRVWDSQTAGIGNAGSCCKPKKKNKSRPAIELDPSHLCKRQNIYATPFYRQLSILLVRTF 545
             .|:|......||    ||    :.:||     ||          .|.:.|.::.|.|:||.|.
plant   381 -EEVSRTFPQDQT----NA----RLRKK-----AI----------TNRWPTSWWMQFSVLLKRG- 420

  Fly   546 LLIWRDSSLTTMR----FAIHLITGIL------------IGTLYFGIGNDAAQTLNIFRYLFYTI 594
            |......|.:.:|    .::.|::|:|            :|.|:                 |::|
plant   421 LKERSHESFSGLRIFMVMSVSLLSGLLWWHSRVAHLQDQVGLLF-----------------FFSI 468

  Fly   595 MFIMYCAFSGILVKFPLEFPIVSREHFNRWYSLRAYYVAITLADLPIQIICSALFIVPTYLMTQQ 659
            .:..:..|:.|.. ||.|.|::.:|..:..|.|.:||:|.|:.|||:::|...:|:..||.|...
plant   469 FWGFFPLFNAIFT-FPQERPMLIKERSSGIYRLSSYYIARTVGDLPMELILPTIFVTITYWMGGL 532

  Fly   660 PLELWRFGMFFLIVFVTALVSQSIGLAVGAAL-SLKLGSILGPFFICPFLQFSGFFLMEKDAPVF 723
            ...|..|.|..:||....||:|.:|||:||.| ..|..:.|....:..||...|:::  :..|.|
plant   533 KPSLTTFIMTLMIVLYNVLVAQGVGLALGAILMDAKKAATLSSVLMLVFLLAGGYYI--QHIPGF 595

  Fly   724 LRWMFDISFLKYSLEGATMAIFGYDREPLACNE-LYCHLRHPQFILKSLDMANGNYTLALIFLFG 787
            :.|:..:||..|..:......:.:| |...|.. |:|.:...:.| |:|.:  ||....::.|..
plant   596 IAWLKYVSFSHYCYKLLVGVQYTWD-EVYECGSGLHCSVMDYEGI-KNLRI--GNMMWDVLALAV 656

  Fly   788 VLVFLRILAF 797
            :|:..|:||:
plant   657 MLLLYRVLAY 666

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9663	NP_608760.2	ABCG_EPDR	145..370	CDD:213180	89/245 (36%)
		3a01204	149..808	CDD:273361	196/690 (28%)
		ABC2_membrane	540..743	CDD:279410	59/219 (27%)
ABCG21	NP_001189973.1	PLN03211	43..670	CDD:215634	203/757 (27%)
		P-loop_NTPase	89..304	CDD:304359	83/221 (38%)
		ABC2_membrane	416..615	CDD:279410	59/219 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0061
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1022017at2759
OrthoFinder	1	1.000	-	-		FOG0000053
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100076
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X52
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.720