DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9663 and ABCG29

DIOPT Version :9

Sequence 1:	NP_608760.2	Gene:	CG9663 / 33541	FlyBaseID:	FBgn0031516	Length:	808	Species:	Drosophila melanogaster
Sequence 2:	NP_566543.1	Gene:	ABCG29 / 820881	AraportID:	AT3G16340	Length:	1416	Species:	Arabidopsis thaliana

Alignment Length:	858	Identity:	188/858 - (21%)
Similarity:	338/858 - (39%)	Gaps:	198/858 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 WSLASAVSPNVTGGDVIRLNHLKSSSETHLPSRGSGTGSGALPRPTTPVPSKKLSSKRPPHLTLN 68
            |..|..|||.....|.:.:|.:.:....:.||..:.|..|
plant   690 WKWAYWVSPMAYTYDALTVNEMLAPRWINQPSSDNSTSLG------------------------- 729

  Fly    69 IKAKSHDAPLAETENTVLSTSESVY----GTPLGATPV-----------SSPANQSQRSQASQHS 118
                     ||..|...:.|..:.|    |..||.|.:           .:|..:.|...:.:::
plant   730 ---------LAVLEIFDIFTDPNWYWIGVGGILGFTVLFNILVTLALTFLNPLEKQQAVVSKENT 785

  Fly   119 DESR-----NTSSTATSGGSIFPHEQYKTIKKINIGFENIRYTTKFGVFQRE---TKD---VLMG 172
            :|:|     .:.|.....|.:.|      ...:.:.|:|:.|........:|   :||   :|..
plant   786 EENRAENGSKSKSIDVKRGMVLP------FTPLTMSFDNVNYYVDMPKEMKEQGVSKDKLQLLKE 844

  Fly   173 LTGYFKSGELSAVIGPSGAGKSTLLNILSGYTTYGF-TGDFRVNGNRRDLKAFKSNVAFIRQDTS 236
            :||.|:.|.|:|::|.|||||:||:::|:|..|.|: .||.|::|..:..:.|.....:..|:..
plant   845 VTGVFRPGVLTALMGVSGAGKTTLMDVLAGRKTGGYIEGDIRISGFPKRQETFARISGYCEQNDI 909

  Fly   237 LQAFLSVKEAMHFAANLKIGTHMTHSEKRERVKCILEAIGMYENRHTRTG-----QLSGGQKKRL 296
            ....::|||::.::|.|::...:|..||...|..::|.:.:...:....|     .||..|:|||
plant   910 HSPQVTVKESLIYSAFLRLPKEVTKYEKMRFVDEVMELVELESLKDAVVGLPGITGLSTEQRKRL 974

  Fly   297 AIALELVNNPPVLILDEPTTGLDSFTSNQLINLLKKLAIEGRTVICTIHQPSALTFAMFDHLYAI 361
            .||:|||.||.::.:||||:|||:..:..::..::.....||||:|||||||...|..||.|..:
plant   975 TIAVELVANPSIIFMDEPTSGLDARAAAIVMRTVRNTVDTGRTVVCTIHQPSIDIFEAFDELLLL 1039

  Fly   362 GE-GKCIYAG----GAQNLLPFLGALN--LHCPESYNPADYLMEI------ATHDYDTAEDNQLE 413
            .. |:.||||    .:..::.:..|::  ....|.||||.:::|:      |..:.|.||..:..
plant  1040 KRGGQVIYAGPLGQNSHKIIEYFQAIHGVPKIKEKYNPATWMLEVSSMAAEAKLEIDFAEHYKTS 1104

  Fly   414 KLVALMDNGRNEDYRQSKTARVAQLAAMKKVDQLMAAGLITPVTAPVMSTSVPAHFMQGNTFKPL 478
            .|           |:|:|                   .|:..::.|....| ..:|
plant  1105 SL-----------YQQNK-------------------NLVKELSTPPQGAS-DLYF--------- 1129

  Fly   479 TPINELSSRVWDSQTAGIGNAGSCCKPKKKNKSRPAIELDPSHLCKRQNIYATPFYRQLSILLVR 543
                  |:|.  ||:. :|...||                                      |.:
plant  1130 ------STRF--SQSL-LGQFKSC--------------------------------------LWK 1147

  Fly   544 TFLLIWRDSSLTTMRFAIHLITGILIGTLYFGIG------NDAAQTLNIFRYLFYTIMFIMYCAF 602
            .::..||.......||...|...:::|::::.:|      ||..:.:..   ::..::|:.....
plant  1148 QWITYWRTPDYNLARFFFTLAAAVMLGSIFWKVGTKRENANDLTKVIGA---MYAAVLFVGVNNS 1209

  Fly   603 SGILVKFPLEFPIVSREHFNRWYSLRAYYVAITLADLPIQIICSALFIVPTYLMTQQPLELWRFG 667
            |.:.....:|..:..||.....||...|.:|..:.::|..:|.:..:.:..|.|......|.:|.
plant  1210 SSVQPLIAVERSVFYRERAAEMYSALPYALAQVVCEIPYVLIQTTYYTLIIYAMMCFEWTLAKFF 1274

  Fly   668 MFFLIVFVTALVSQSIG-LAVGAALSLKLGSILGPFFICPFLQFSGFFLMEKDAPVFLRWMFDIS 731
            .|:.:.|::.|.....| :.|....:.::.::....|...|..||||.:.....|.:..|.:.|.
plant  1275 WFYFVSFMSFLYFTYYGMMTVALTPNQQVAAVFAGAFYGLFNLFSGFVIPRPRIPKWWIWYYWIC 1339

  Fly   732 FLKYSLEGA----------TMAIFGYDREPLACNELYCHLRHPQFILKSLDMANGNYTL--ALIF 784
            .:.:::.|.          |:.:.|...:|.....:..|..:....:..:......:||  |.:|
plant  1340 PVAWTVYGLIVSQYGDVEDTIKVPGMANDPTIKWYIENHYGYDADFMIPIATVLVGFTLFFAFMF 1404

  Fly   785 LFGVLVFLRILAF 797
            .||:    |.|.|
plant  1405 AFGI----RTLNF 1413

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9663	NP_608760.2	ABCG_EPDR	145..370	CDD:213180	80/237 (34%)
		3a01204	149..808	CDD:273361	161/693 (23%)
		ABC2_membrane	540..743	CDD:279410	41/219 (19%)
ABCG29	NP_566543.1	PLN03140	1..1416	CDD:215599	188/858 (22%)
		ABC_trans_N	54..141	CDD:291196
		ABCG_PDR_domain1	156..402	CDD:213200
		ABC2_membrane	503..709	CDD:279410	6/18 (33%)
		PDR_assoc	716..780	CDD:285559	15/97 (15%)
		ABCG_PDR_domain2	811..1049	CDD:213199	80/237 (34%)
		ABC2_membrane	1144..1351	CDD:279410	41/247 (17%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X52
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.910