DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9663 and ABCG1

DIOPT Version :9

Sequence 1:	NP_608760.2	Gene:	CG9663 / 33541	FlyBaseID:	FBgn0031516	Length:	808	Species:	Drosophila melanogaster
Sequence 2:	NP_181467.1	Gene:	ABCG1 / 818520	AraportID:	AT2G39350	Length:	740	Species:	Arabidopsis thaliana

Alignment Length:	808	Identity:	189/808 - (23%)
Similarity:	326/808 - (40%)	Gaps:	161/808 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    65 LTLNIKAKSHDAPLAETENTVLSTSESVYGTPLGATPVSSPANQSQRSQASQHSDESRNTSSTAT 129
            :.||..:..||:.|.:....|....:...|   ..|||....||       .::|....|.....
plant    13 MELNTISSIHDSTLGQLLKNVSDVRKMAIG---DETPVHESLNQ-------DYNDGYMRTVPFVL 67

  Fly   130 SGGSIFPHEQYKTIKKINIGFENI---RYTTKFGVFQR---ETKDVLMGLTGYFKSGELSAVIGP 188
            |    |.:..|....:..:.|.|:   |.|....:.|.   :||.:|..::|..:.||:.||:|.
plant    68 S----FDNLTYNVSVRPKLDFRNLFPRRRTEDPEIAQTARPKTKTLLNNISGETRDGEIMAVLGA 128

  Fly   189 SGAGKSTLLNILSGYTTYG-FTGDFRVNGNRRDLKAFKSNVAFIRQDTSLQAFLSVKEAMHFAAN 252
            ||:|||||::.|:.....| ..|..::||.....:..|...|::.||..|...|:|:|.:.|||.
plant   129 SGSGKSTLIDALANRIAKGSLKGTVKLNGETLQSRMLKVISAYVMQDDLLFPMLTVEETLMFAAE 193

  Fly   253 LKIGTHMTHSEKRERVKCILEAIGMYENRHTRTGQ-----LSGGQKKRLAIALELVNNPPVLILD 312
            .::...:..|:|:.||:.:::.:|:.....|..|.     :|||:::|::|.::::::|.:|.||
plant   194 FRLPRSLPKSKKKLRVQALIDQLGIRNAAKTIIGDEGHRGISGGERRRVSIGIDIIHDPILLFLD 258

  Fly   313 EPTTGLDSFTSNQLINLLKKLAIEGRTVICTIHQPSALTFAMFDHLYAIGEGKCIYAGGAQNLLP 377
            |||:||||.::..::.:||::|..|..||.:|||||.....:.|.|..:..|..:|:|...:|..
plant   259 EPTSGLDSTSAFMVVKVLKRIAQSGSIVIMSIHQPSHRVLGLLDRLIFLSRGHTVYSGSPASLPR 323

  Fly   378 FLGALNLHCPESYNPADYLMEIATHDYDTAEDNQLEKLVALMDNGR-----NEDYRQSKTARVAQ 437
            |........||:.|..::.:::            :.:|.......|     |:.:::
plant   324 FFTEFGSPIPENENRTEFALDL------------IRELEGSAGGTRGLIEFNKKWQE-------- 368

  Fly   438 LAAMKKVDQLMAAGLITPVTAP----VMSTSVPAHFMQGNTFKPLTPINELSSRVWDSQTAGIGN 498
               |||  |......:||.::|    .:..::.|...:|..             |...::...|.
plant   369 ---MKK--QSNRQPPLTPPSSPYPNLTLKEAIAASISRGKL-------------VSGGESVAHGG 415

  Fly   499 AGSCCKPKKKNKSRPAIELDPSHLCKRQNIYATPFYRQLSILLVRTFLLIWRDSSLTTMRFAIHL 563
            |.:       |.:..|:   |:        :|.|.:.::..|..|:.|...|...|..:|.|..:
plant   416 ATT-------NTTTLAV---PA--------FANPMWIEIKTLSKRSMLNSRRQPELFGIRIASVV 462

  Fly   564 ITGILIGTLYFGIGND---AAQTLNIFRY----LFYTIMFIMYCAFSGILVKFPLEFPIVSREHF 621
            |||.::.|:::.:.|.   ..:.|..|.:    :|||      ||  ..|..|..|..|..||..
plant   463 ITGFILATVFWRLDNSPKGVQERLGFFAFAMSTMFYT------CA--DALPVFLQERYIFMRETA 519

  Fly   622 NRWYSLRAYYVAITLADLPIQIICSALFIVPTYLMTQQPLELWRFG--------MFFLIVFVTAL 678
            ...|...:|.::..:...|..|..|..|...||         |..|        :|:.::.:.:.
plant   520 YNAYRRSSYVLSHAIVSFPSLIFLSVAFAATTY---------WAVGLDGGLTGLLFYCLIILASF 575

  Fly   679 VSQS--IGLAVGAALSLKLGSILGPFFICPFLQFSGFFLMEKDAPVFLRWMFDISFLKYSLEGAT 741
            .|.|  :....|...|:.||..:....:..||.|||||:.....|.:..|...:|.:||..|...
plant   576 WSGSSFVTFLSGVVPSVMLGYTIVVAILAYFLLFSGFFINRNRIPDYWIWFHYMSLVKYPYEAVL 640

  Fly   742 MAIFG------------YDREPLACNELYCHLRHPQFILKSLDMANGNYT--------------- 779
            ...|.            :|..||........|:....:.|||.:...:.|
plant   641 QNEFSDATKCFVRGVQIFDNTPLGELPEVMKLKLLGTVSKSLGVTISSTTCLTTGSDILRQQGVV 705

  Fly   780 -------LALIFLFGVLVFLRILAFYIM 800
                   |.:...||  .|.|||.::.:
plant   706 QLSKWNCLFITVAFG--FFFRILFYFTL 731

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9663	NP_608760.2	ABCG_EPDR	145..370	CDD:213180	75/236 (32%)
		3a01204	149..808	CDD:273361	172/724 (24%)
		ABC2_membrane	540..743	CDD:279410	55/219 (25%)
ABCG1	NP_181467.1	3a01204	106..739	CDD:273361	167/701 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0061
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1022017at2759
OrthoFinder	1	1.000	-	-		FOG0000053
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100076
Panther	1	1.100	-	-	O	PTHR48041
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.820