Protein Alignment CG9663 and ABCG5

DIOPT Version :9

• Sequence 1: NP_608760.2
• Gene: CG9663 / 33541
• FlyBaseID: FBgn0031516
• Length: 808
• Species: Drosophila melanogaster
• Sequence 2: NP_071881.1
• Gene: ABCG5 / 64240
• HGNCID: 13886
• Length: 651
• Species: Homo sapiens
• Alignment Length: 761
• Identity: 184/761 - (24%)
• Similarity: 309/761 - (40%)
• Gaps: 178/761 - (23%)

  Fly   100 TPVSSPANQSQRSQASQHSDESRNTSSTATSGGSIFPHEQYKTIKKINIGFENIRYTTKFGV--- 161
            ||..|...|..|  .||.|.|  ...:||..     ||         ::|..:..|:....|
Human     8 TPGGSMGLQVNR--GSQSSLE--GAPATAPE-----PH---------SLGILHASYSVSHRVRPW 54

  Fly   162 ------FQRETKDVLMGLTGYFKSGELSAVIGPSGAGKSTLLNILSGYTTYG--FTGDFRVNGNR 218
                  .|:.|:.:|..::.|.:||::..::|.||:||:|||:.:||.....  |.|:..|||..
Human    55 WDITSCRQQWTRQILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGRLGRAGTFLGEVYVNGRA 119

  Fly   219 RDLKAFKSNVAFIRQDTSLQAFLSVKEAMHFAANLKI--GTHMTHSEKRERVKCIL-------EA 274
            ...:.|:...:::.|..:|.:.|:|:|.:|:.|.|.|  |...:..:|.|.|...|       ..
Human   120 LRREQFQDCFSYVLQSDTLLSSLTVRETLHYTALLAIRRGNPGSFQKKVEAVMAELSLSHVADRL 184

  Fly   275 IGMYENRHTRTGQLSGGQKKRLAIALELVNNPPVLILDEPTTGLDSFTSNQLINLLKKLAIEGRT 339
            ||.|.     .|.:|.|:::|::||.:|:.:|.|::.||||||||..|:||::.||.:||...|.
Human   185 IGNYS-----LGGISTGERRRVSIAAQLLQDPKVMLFDEPTTGLDCMTANQIVVLLVELARRNRI 244

  Fly   340 VICTIHQPSALTFAMFDHLYAIGEGKCIYAGGAQNLLPFLGALNLHCPESYNPADYLMEIATHDY 404
            |:.|||||.:..|.:||.:..:..|:.|:.|....:|.|.......|||..||.|:.|::.:.|.
Human   245 VVLTIHQPRSELFQLFDKIAILSFGELIFCGTPAEMLDFFNDCGYPCPEHSNPFDFYMDLTSVDT 309

  Fly   405 DTAE-DNQLEKLVALMDNGRNEDYRQS----KTARVAQLAAMKKVDQLMAAGLITPVTAPVMSTS 464
            .:.| :.:..|.|.::::.    |::|    ||.:  .:..||.:..|
Human   310 QSKEREIETSKRVQMIESA----YKKSAICHKTLK--NIERMKHLKTL----------------- 351

  Fly   465 VPAHFMQGNTFKPLTPINELSSRVWDSQTAGIGNAGSCCKPKKKNKSRPAIELDPSHLCKR---- 525
                        |:.|.                          |.|..|.:......|.:|
Human   352 ------------PMVPF--------------------------KTKDSPGVFSKLGVLLRRVTRN 378

  Fly   526 --QNIYATPFYRQLSILLVRTFLLIWRDSSLTTMRFAIHLITGILIGTLYFGIGNDAAQTLNIFR 588
              :|..|. ..|.|..|::..|||.          |.:.:.:.:|.|.:...:|
Human   379 LVRNKLAV-ITRLLQNLIMGLFLLF----------FVLRVRSNVLKGAIQDRVG----------- 421

  Fly   589 YLFYTIMFIMYCAFSGILVKFPLEFPI---VSREH-----FNRWYSLRAYYVAITLADLPIQIIC 645
             |.|  .|:....::|:|....| ||:   ||.:.     :.:|..:.||.:.:    ||..::.
Human   422 -LLY--QFVGATPYTGMLNAVNL-FPVLRAVSDQESQDGLYQKWQMMLAYALHV----LPFSVVA 478

  Fly   646 SALFIVPTYLMTQQPLELWRFGMFFLIVFVTALVSQSIGLAVGAALSLKLGSILGP--------- 701
            :.:|....|.......|:.|||.|...:....|:.:.:.|.:       ||.:..|
Human   479 TMIFSSVCYWTLGLHPEVARFGYFSAALLAPHLIGEFLTLVL-------LGIVQNPNIVNSVVAL 536

  Fly   702 FFICPFLQFSGFFLMEKDAPVFLRWMFDISFLKYSLEGATMAIF-------GYDREPLACNELYC 759
            ..|...|..|||....::.|:..:.:...:|.||..|...:..|       |.....:..|.:..
Human   537 LSIAGVLVGSGFLRNIQEMPIPFKIISYFTFQKYCSEILVVNEFYGLNFTCGSSNVSVTTNPMCA 601

  Fly   760 HLRHPQFILKSLDMANGNYTLALIFLFGVLVFLRILAFYIMSFRLR 805
            ..:..|||.|:...|...:|:..:.|:..:..|.||.  |:.|::|
Human   602 FTQGIQFIEKTCPGATSRFTMNFLILYSFIPALVILG--IVVFKIR 645

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9663	NP_608760.2	ABCG_EPDR	145..370	CDD:213180	78/244 (32%)
		3a01204	149..808	CDD:273361	171/712 (24%)
		ABC2_membrane	540..743	CDD:279410	45/219 (21%)
ABCG5	NP_071881.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..32		9/27 (33%)
		ABCG_White	50..275	CDD:213201	76/229 (33%)
		3a01204	60..645	CDD:273361	167/689 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1022017at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.920