DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9663 and abca3b

DIOPT Version :9

Sequence 1:	NP_608760.2	Gene:	CG9663 / 33541	FlyBaseID:	FBgn0031516	Length:	808	Species:	Drosophila melanogaster
Sequence 2:	XP_009297489.1	Gene:	abca3b / 564344	ZFINID:	ZDB-GENE-050517-2	Length:	1703	Species:	Danio rerio

Alignment Length:	528	Identity:	111/528 - (21%)
Similarity:	207/528 - (39%)	Gaps:	113/528 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    93 YGTP-------LGATPVSSPANQSQRSQASQHSDESRNTSSTATSGGSIFPHEQYKTIKKINIGF 150
            ||.|       |.:...|||.....:.:..:...|.       .|.|.....|....:..:.|
Zfish   475 YGVPQPWYFFILPSYWCSSPRVAFLKEKEDEEDAEK-------ASKGEFMEEEPAGLVAGVKI-- 530

  Fly   151 ENIRYTTKFGVFQRETKDVLMGLTGYFKSGELSAVIGPSGAGKSTLLNILSGYTTYGFTGDFRVN 215
            :.:....|.|   .::|:.:..||.....|:::.::|.:||||:|.|::|:|..... :|...:|
Zfish   531 KRLAKVFKVG---NKSKEAVRDLTLNMFEGQITVLLGHNGAGKTTTLSMLTGLFPPS-SGRAYIN 591

  Fly   216 GNR--RDLKAFKSNVAFIRQDTSLQAFLSVKEAMHFAANLKIGTHMTHSEKRER----VKCILEA 274
            |..  :|:...:.::....|...|...|:|:|.:.|...||       ...||:    |..|:..
Zfish   592 GYDICQDMALIRRSLGLCPQHDVLFDNLTVREHLLFYTQLK-------GYPREKIPGEVDRIIRI 649

  Fly   275 IGMYENRHTRTGQLSGGQKKRLAIALELVNNPPVLILDEPTTGLDSFTSNQLINLLKKLAIEGRT 339
            :.:.:.|:.:...||||.|::|:|.:.|:.:..|::|||||:|:|........:||:. ...|||
Zfish   650 LNLEDKRNAKCKTLSGGMKRKLSIGIALIGDSKVVMLDEPTSGMDPSARRATWDLLQG-EKRGRT 713

  Fly   340 VICTIHQPSALTFAMFDH---------LYAIGEGKCI---------YAGGAQ---------NLLP 377
            ::.|.|        ..|.         :.|.||.:|.         |..|..         |:..
Zfish   714 ILLTTH--------FMDEADLLGDRIAIMASGELQCCGSPLFLKNKYGAGYHMVIVKDAFCNVSE 770

  Fly   378 FLGALNLHCPESYNPADYLMEIATHDYDTAEDNQLEKLVALMDNGRNE----DYRQSKTARVAQL 438
            ....::::.|::...:....|: ::.......::.|.|.|.::..|:|    .|..|.|
Zfish   771 ITRLVHMYVPDATLESSAGAEL-SYILPKESTSRFELLFAELEMNRDELGIASYGASVT------ 828

  Fly   439 AAMKKVDQLMAAGLITPVTAPVMSTSVPAHFMQGNTFKPLTPINELSSRVW----DSQTAGIGN- 498
             .|::|  .:..|.:...:..:.:..:||...|          :|..|..|    .|..:|:.:
Zfish   829 -TMEEV--FLRVGKLVDSSLDIQAIQLPALQYQ----------HERRSHDWTMDDSSSISGMTDV 880

  Fly   499 ---AGSCCKPKKKNKSRPAIELDPSHLCKRQNIYATPFYRQLSILLVRTFLLIWRDSSLTTMRFA 560
               ..||          ..|..|.|::  :.|..|..:.:|...:.::..|..||:..:...:|.
Zfish   881 TDFTDSC----------TMISEDGSNI--KLNTGARLYMQQFYAMFLKRALYSWRNWKVMVAQFL 933

  Fly   561 IHLITGIL 568
            :.||..:|
Zfish   934 VPLIFTVL 941

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9663	NP_608760.2	ABCG_EPDR	145..370	CDD:213180	62/248 (25%)
		3a01204	149..808	CDD:273361	99/465 (21%)
		ABC2_membrane	540..743	CDD:279410	7/29 (24%)
abca3b	XP_009297489.1	AAA	1..>95	CDD:333001
abca3b	XP_009297489.1	AAA	<122..1695	CDD:333001	111/528 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.000