DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9663 and Atet

DIOPT Version :9

Sequence 1:	NP_608760.2	Gene:	CG9663 / 33541	FlyBaseID:	FBgn0031516	Length:	808	Species:	Drosophila melanogaster
Sequence 2:	NP_001097079.1	Gene:	Atet / 33636	FlyBaseID:	FBgn0020762	Length:	832	Species:	Drosophila melanogaster

Alignment Length:	857	Identity:	287/857 - (33%)
Similarity:	455/857 - (53%)	Gaps:	100/857 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 LASAVSPN-------VTGGDVIRLNHLKSSSETHLPSRGSGTGSGALPRPTTPVPSKKLSSKRPP 63
            |.:|.|||       .|..:.:    |.:|....|.:..:|:|:   |.|.   |:...:|::.|
  Fly    22 LPAAKSPNRVSDSAATTAPNAV----LYTSGNMSLSTLSTGSGN---PNPN---PNASTNSRQEP 76

  Fly    64 -------HLTLNIKAKSHDAPLAETENTVLSTSESVYGTPLGATPVSSPANQSQRSQASQHSDES 121
                   .||.::|..||.     ::|.:.:..       ||:.      |.:...:.:.:|..|
  Fly    77 VPLLSQLKLTNDLKQNSHG-----SQNNLCNGG-------LGSN------NHALAPKVANNSGGS 123

  Fly   122 RNTSSTATSGGSIFPHEQYKTIKKINIGFENIRYTTKFGVFQRETKDVLMGLTGYFKSGELSAVI 186
            .|.....|...|..|..     ..::|.|.:|.|:.. ...:|..|.:|..::|.|::||::|::
  Fly   124 PNGQKKGTIALSHLPQR-----PPVDIEFCDISYSVT-DSHRRGFKTILKSVSGKFRNGEITAIM 182

  Fly   187 GPSGAGKSTLLNILSGYTTYGFTGDFRVNGNRRDLKAFKSNVAFIRQDTSLQAFLSVKEAMHFAA 251
            ||||||||||:|||:||.|...:|...:|...|:|:.|:....:|.||..|.|.|:|:|||..||
  Fly   183 GPSGAGKSTLMNILAGYKTAQLSGSVLINSKERNLRRFRKLSCYIMQDDVLIANLTVREAMMVAA 247

  Fly   252 NLKIGTHMTHSEKRERVKCILEAIGMYENRHTRTGQLSGGQKKRLAIALELVNNPPVLILDEPTT 316
            |||:|.:|....|...|:.|||.||:.|:.:|.|..|||||:|||:|||||||||||:..||||:
  Fly   248 NLKLGKNMISYAKVVVVEEILETIGLKESVNTLTCNLSGGQRKRLSIALELVNNPPVMFFDEPTS 312

  Fly   317 GLDSFTSNQLINLLKKLAIEGRTVICTIHQPSALTFAMFDHLYAIGEGKCIYAGGAQNLLPFLGA 381
            ||||.|..|||:||:.||..|||::||||||||..|..|||||.:.:|:|:|.|..:.|:|:|.:
  Fly   313 GLDSSTCFQLISLLRSLARGGRTIVCTIHQPSARLFEKFDHLYLLAQGQCVYEGRVKGLVPYLSS 377

  Fly   382 LNLHCPESYNPADYLMEIATHDYDTAEDNQLEKLVALMDNGRNEDY-RQSKTARVAQLAAMKKVD 445
            |...||..:|||||::|:|:.:|..|    :.|||..:.:|..:.| .:.....:||......:.
  Fly   378 LGYECPSYHNPADYVLEVASGEYGDA----VPKLVDAVKSGACKKYAHKDYVLTLAQKGCNNDII 438

  Fly   446 QLMAAGLITPVTAPVMSTSVPAHFMQGNTFKPLTPINE--------------------------- 483
            :...:|....:....:....|.  ::....:|..|:::
  Fly   439 KGSGSGAENAMAILTLEDEKPP--LEDRQLEPSIPVDDPAELKPPKLETQQSQNSDCSVVNMPTN 501

  Fly   484 --------LSSRVWDSQTAGIGNAGSC----CKPKKKNKSRPAIELDPSHLCKRQNIYATPFYRQ 536
                    .||:...:...|.|:.|..    |.....:.....:.|      ..:..:.|..:.|
  Fly   502 AVDDSCSFSSSKGTQNAVGGSGSGGPSAVVGCMTSLLDSHESVVTL------PNKTGFPTSGWTQ 560

  Fly   537 LSILLVRTFLLIWRDSSLTTMRFAIHLITGILIGTLYFGIGNDAAQTLNIFRYLFYTIMFIMYCA 601
            ..|||.|:|..|.||..||.||...|:|.|.:||.:|:.:||:|::.::....:|:..:|..:.|
  Fly   561 FWILLKRSFRTILRDKMLTHMRLFSHVIVGAIIGMIYYDVGNEASKIMSNAGCIFFVSLFTTFTA 625

  Fly   602 FSGILVKFPLEFPIVSREHFNRWYSLRAYYVAITLADLPIQIICSALFIVPTYLMTQQPLELWRF 666
            ....::.||.|..:..|||.|.||||:|:|.|.|:||:|.||:.|:::::..|.:|.||:||.|.
  Fly   626 MMPTILTFPTEMSVFVREHLNYWYSLKAFYFAKTIADMPFQIVFSSVYVLVVYYLTSQPMELERV 690

  Fly   667 GMFFLIVFVTALVSQSIGLAVGAALSLKLGSILGPFFICPFLQFSGFFLMEKDAPVFLRWMFDIS 731
            .||.||..:.:||:||:||.:||.::::.|..|||....|.:.|||||:.....|.:|:|:..:|
  Fly   691 SMFVLICVLNSLVAQSLGLLIGAGMNIETGVFLGPVTTIPTILFSGFFVNFDTIPGYLQWVTYVS 755

  Fly   732 FLKYSLEGATMAIFGYDREPLACNELYCHLRHPQFILKSLDMANGNYTLALIFLFGVLVFLRILA 796
            :::|..|||.:||:|.||..:.||::|||.|.|:..|:.:.|.|..:.:..:.|.|:...|||:|
  Fly   756 YVRYGFEGAMVAIYGMDRAKMQCNQMYCHYRVPKKFLEEMSMDNALFWVDAVALIGIFFALRIIA 820

  Fly   797 FYIMSFRLRLFR 808
            ::::.::|.:.|
  Fly   821 YFVLRWKLHMIR 832

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9663	NP_608760.2	ABCG_EPDR	145..370	CDD:213180	115/224 (51%)
		3a01204	149..808	CDD:273361	254/698 (36%)
		ABC2_membrane	540..743	CDD:279410	81/202 (40%)
Atet	NP_001097079.1	3a01204	137..825	CDD:273361	255/705 (36%)
		ABCG_EPDR	142..366	CDD:213180	115/224 (51%)
		ABC2_membrane	564..767	CDD:279410	81/202 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45468862
Domainoid	1	1.000	121	1.000	Domainoid score	I1855
eggNOG	1	0.900	-	-		E2759_KOG0061
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG28143
OrthoDB	1	1.010	-	-		D177791at33208
OrthoFinder	1	1.000	-	-		FOG0000053
OrthoInspector	1	1.000	-	-		mtm14984
orthoMCL	1	0.900	-	-		OOG6_100076
Panther	1	1.100	-	-	P	PTHR48041
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X52
	11	10.760