Protein Alignment CG9663 and Abcg5

DIOPT Version :10

• Sequence 1: NP_608760.2
• Gene: CG9663 / 33541
• FlyBaseID: FBgn0031516
• Length: 808
• Species: Drosophila melanogaster
• Sequence 2: NP_114090.1
• Gene: Abcg5 / 27409
• MGIID: 1351659
• Length: 652
• Species: Mus musculus
• Alignment Length: 768
• Identity: 178/768 - (23%)
• Similarity: 303/768 - (39%)
• Gaps: 183/768 - (23%)

  Fly    97 LGATPVSSP----------ANQSQRSQASQHSDESRNTSSTATSGGSIFPHEQYKTIKKINIGFE 151
            :|..|..||          .:.|...|.|....|:|::....        |..|....::. .:.
Mouse     1 MGELPFLSPEGARGPHINRGSLSSLEQGSVTGTEARHSLGVL--------HVSYSVSNRVG-PWW 56

  Fly   152 NIRYTTKFGVFQRETKDVLMGLTGYFKSGELSAVIGPSGAGKSTLLNILSG--YTTYGFTGDFRV 214
            ||:     ...|:..:.:|..::.|.:||::..::|.||:||:|||:.:||  ..|....|:..|
Mouse    57 NIK-----SCQQKWDRQILKDVSLYIESGQIMCILGSSGSGKTTLLDAISGRLRRTGTLEGEVFV 116

  Fly   215 NG--NRRDLKAFKSNVAFIRQDTSLQAFLSVKEAMHFAANLKI--GTHMTHSEKRERVKCIL--- 272
            ||  .|||  .|:...:::.|.....:.|:|:|.:.:.|.|.:  .:...:::|.|.|...|
Mouse   117 NGCELRRD--QFQDCFSYVLQSDVFLSSLTVRETLRYTAMLALCRSSADFYNKKVEAVMTELSLS 179

  Fly   273 ----EAIGMYENRHTRTGQLSGGQKKRLAIALELVNNPPVLILDEPTTGLDSFTSNQLINLLKKL 333
                :.||.|     ..|.:|.|:::|::||.:|:.:|.|::|||||||||..|:||::.||.:|
Mouse   180 HVADQMIGSY-----NFGGISSGERRRVSIAAQLLQDPKVMMLDEPTTGLDCMTANQIVLLLAEL 239

  Fly   334 AIEGRTVICTIHQPSALTFAMFDHLYAIGEGKCIYAGGAQNLLPFLGALNLHCPESYNPADYLME 398
            |...|.||.|||||.:..|..||.:..:..|:.::.|..:.:|.|.......|||..||.|:.|:
Mouse   240 ARRDRIVIVTIHQPRSELFQHFDKIAILTYGELVFCGTPEEMLGFFNNCGYPCPEHSNPFDFYMD 304

  Fly   399 IATHDYDTAEDNQLEKLVALMDNGRNEDYRQSKTARVAQLAAMKKVDQLMAAGLITPVTAPVMST 463
            :      |:.|.|                     :|..::...|:|..|..|...:.:...::..
Mouse   305 L------TSVDTQ---------------------SREREIETYKRVQMLECAFKESDIYHKILEN 342

  Fly   464 SVPAHFMQGNTFKPLTPINELSSRVWDSQTAGIGNAGSCCKPKKKNKSRPAIELDPSHLCKRQNI 528
            ...|.:::   ..|..|.                          |.|..|.:
Mouse   343 IERARYLK---TLPTVPF--------------------------KTKDPPGM------------- 365

  Fly   529 YATPFYRQLSILLVRTFLLIWRDSSLTTMRFAIHLITGILIGTLYFGIGNDAAQ--TLNIFRYLF 591
                 :.:|.:||.|....:.|:.....||...:||.|:.:......:.|:..:  ..:....|:
Mouse   366 -----FGKLGVLLRRVTRNLMRNKQAVIMRLVQNLIMGLFLIFYLLRVQNNTLKGAVQDRVGLLY 425

  Fly   592 YTIMFIMYCAFSGILVKFPLEFPIVSREH----FNRWYSLRAYYVAITLADLPIQIICSALFIVP 652
            ..:....|......:..||:...:..:|.    :::|..|.||.:.:    ||..:|.:.:|...
Mouse   426 QLVGATPYTGMLNAVNLFPMLRAVSDQESQDGLYHKWQMLLAYVLHV----LPFSVIATVIFSSV 486

  Fly   653 TYLMTQQPLELWRFGMFFLIVFVTALVSQSIGL-------------AVGAALSLKLGSILGPFFI 704
            .|.......|:.|||.|...:....|:.:.:.|             ::.|.||:. |.::|
Mouse   487 CYWTLGLYPEVARFGYFSAALLAPHLIGEFLTLVLLGIVQNPNIVNSIVALLSIS-GLLIG---- 546

  Fly   705 CPFLQFSGFFLMEKDAPVFLRWMFDISFLKYSLEGATMAIFGYDREPLACNELY-----C----- 759
                  |||....::.|:.|:.:...:|.||..            |.|..||.|     |
Mouse   547 ------SGFIRNIQEMPIPLKILGYFTFQKYCC------------EILVVNEFYGLNFTCGGSNT 593

  Fly   760 -HLRHP--------QFILKSLDMANGNYTLALIFLFGVLVFLRILAFYIMSFR 803
             .|.||        |||.|:...|...:|...:.|:|.:..|.||...|...|
Mouse   594 SMLNHPMCAITQGVQFIEKTCPGATSRFTANFLILYGFIPALVILGIVIFKVR 646

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9663	NP_608760.2	3a01204	149..808	CDD:273361	167/706 (24%)
Abcg5	NP_114090.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..25		5/23 (22%)
		ABCG_White	50..276	CDD:213201	76/238 (32%)
		3a01204	61..646	CDD:273361	164/692 (24%)