Protein Alignment CG9664 and ABCG1

DIOPT Version :9

• Sequence 1: NP_722889.1
• Gene: CG9664 / 33540
• FlyBaseID: FBgn0031515
• Length: 609
• Species: Drosophila melanogaster
• Sequence 2: XP_024307909.1
• Gene: ABCG1 / 9619
• HGNCID: 73
• Length: 786
• Species: Homo sapiens
• Alignment Length: 589
• Identity: 232/589 - (39%)
• Similarity: 347/589 - (58%)
• Gaps: 41/589 - (6%)

  Fly    37 KGSTPIINEACGVFKSGRLTAILGPSGAGKSTLLNALAGFKLQGVTGQFLLNGRPRDIMSFRKMS 101
            :|...::....|.|.||.|.||:||||||||||:|.|||::..|:.|..|:||.|||:..|||:|
Human   203 EGYKTLLKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYRETGMKGAVLINGLPRDLRCFRKVS 267

  Fly   102 AYIAQNFVMLNLLTVEETLRVSTDLKMPSSTAAQEK----QKIIDDIIDILQLQSCRRTLVKNLS 162
            .||.|:.::|..|||:|.:.||..||:      |||    ::::.:|:..|.|.||..|...:||
Human   268 CYIMQDDMLLPHLTVQEAMMVSAHLKL------QEKDEGRREMVKEILTALGLLSCANTRTGSLS 326

  Fly   163 GGEHKRLSIGIELVTNPPIMFFDEPTSGLDCVGSYQVICHLQRLAHDGRIVVCVVHQPGSRLFQL 227
            ||:.|||:|.:|||.|||:|||||||||||....:||:..::.||..||.::|.:|||.::||:|
Human   327 GGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKGLAQGGRSIICTIHQPSAKLFEL 391

  Fly   228 FDDVLVLAHGEVLYAGEQREMLPTFAQSGHICPQYYNPADFALEVCS-----QSSTTER------ 281
            ||.:.||:.|:.:|.|:...::|.....|..||.|:|||||.:||.|     |:|...|
Human   392 FDQLYVLSQGQCVYRGKVCNLVPYLRDLGLNCPTYHNPADFVMEVASGEYGDQNSRLVRAVREGM 456

  Fly   282 CESLITQ--------NKMMHSTASNVVKLQVDEETALIDVHKDALDLSHLRG--KEQVGFWTQLS 336
            |:|...:        |..:....|..||    :...|..:.||:   |.:.|  .......||..
Human   457 CDSDHKRDLGGDAEVNPFLWHRPSEEVK----QTKRLKGLRKDS---SSMEGCHSFSASCLTQFC 514

  Fly   337 VLLRRHLRSMSRDMFAVQMRLVMHVVVALLLGVVYWQIGGDAQKIVSNVSCLFFVILFVFAGNAM 401
            :|.:|...|:.||.....:|:..|:.:.||:|::|..||.:|:|::||...|||.:||:.....|
Human   515 ILFKRTFLSIMRDSVLTHLRITSHIGIGLLIGLLYLGIGNEAKKVLSNSGFLFFSMLFLMFAALM 579

  Fly   402 PSILLCMQDSAVFIREYYNGWYSLGAYYLSKVLADLPLQLTCPTMFISIGYFMTGQPPEFQRFAM 466
            |::|....:..||:||:.|.||||.||||:|.:||:|.|:..|..:.||.|:||.||.:..||.:
Human   580 PTVLTFPLEMGVFLREHLNYWYSLKAYYLAKTMADVPFQIMFPVAYCSIVYWMTSQPSDAVRFVL 644

  Fly   467 CWALCVMTAFIGHFIGVIAGSLFT-MQLAIFLVPSATIPFLLFSGFFIRLNELSWFLRPICDVSF 530
            ..||..||:.:...:|::.|:..| :|:|.|:.|...||.|||||||:..:.:..:|:.:..:|:
Human   645 FAALGTMTSLVAQSLGLLIGAASTSLQVATFVGPVTAIPVLLFSGFFVSFDTIPTYLQWMSYISY 709

  Fly   531 FRYIFEGLMRAIYGYDRGELECYATSNFCYYRTAEQFLKDFQMEGNEFDWDMAVLGIFLI-LLLL 594
            .||.|||::.:|||.||.:|.| .....|:::.:|..|::..:|..:...|..|||||.| |.|:
Human   710 VRYGFEGVILSIYGLDREDLHC-DIDETCHFQKSEAILRELDVENAKLYLDFIVLGIFFISLRLI 773

  Fly   595 AFFV 598
            |:||
Human   774 AYFV 777

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9664	NP_722889.1	ABCG_EPDR	20..243	CDD:213180	99/209 (47%)
		EcfA2	23..247	CDD:224047	100/213 (47%)
		ABC2_membrane	338..539	CDD:279410	80/201 (40%)
		YadH	<388..547	CDD:223912	66/159 (42%)
ABCG1	XP_024307909.1	3a01204	202..786	CDD:273361	232/589 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0061
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1022017at2759
OrthoFinder	1	1.000	-	-		FOG0000053
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR48041
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R138
SonicParanoid	1	1.000	-	-		X52
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	8	7.910