DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9664 and ABCG39

DIOPT Version :9

Sequence 1:	NP_722889.1	Gene:	CG9664 / 33540	FlyBaseID:	FBgn0031515	Length:	609	Species:	Drosophila melanogaster
Sequence 2:	NP_176867.2	Gene:	ABCG39 / 843013	AraportID:	AT1G66950	Length:	1454	Species:	Arabidopsis thaliana

Alignment Length:	670	Identity:	180/670 - (26%)
Similarity:	301/670 - (44%)	Gaps:	152/670 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 GPQKQ-----KALELHFSQVSY--------SLKGATKGSTPIINEACGVFKSGRLTAILGPSGAG 65
            ||::.     :.|.|.|:.|:|        ..:|.......::.:..|.|:.|.|||::|.||||
plant   839 GPKRGMVLPFQPLSLAFNNVNYYVDMPSEMKAQGVEGDRLQLLRDVGGAFRPGILTALVGVSGAG 903

  Fly    66 KSTLLNALAGFKLQG-VTGQFLLNGRPRDIMSFRKMSAYIAQNFVMLNLLTVEETLRVSTDLKMP 129
            |:||::.|||.|..| :.|...::|.|::..:|.::|.|..||.:....:||.|:|..|..|::.
plant   904 KTTLMDVLAGRKTGGYIEGSISISGYPKNQTTFARVSGYCEQNDIHSPHVTVYESLIYSAWLRLS 968

  Fly   130 SSTAAQEKQKIIDDIIDILQLQSCRRTL-----VKNLSGGEHKRLSIGIELVTNPPIMFFDEPTS 189
            :....:.::..:::::::::|:..|.::     |..||..:.|||:|.:|||.||.|:|.|||||
plant   969 TDIDIKTRELFVEEVMELVELKPLRNSIVGLPGVDGLSTEQRKRLTIAVELVANPSIIFMDEPTS 1033

  Fly   190 GLDCVGSYQVICHLQRLAHDGRIVVCVVHQPGSRLFQLFDDVLVLAH-GEVLYA---GEQREMLP 250
            |||...:..|:..::.....||.|||.:|||...:|:.||::|::.. |:|:||   |...:.|.
plant  1034 GLDARAAAIVMRTVRNTVDTGRTVVCTIHQPSIDIFESFDELLLMKRGGQVIYAGSLGHHSQKLV 1098

  Fly   251 TFAQSGHICPQY---YNPADFALEVCSQSSTTERCES-------LITQNKMMHSTASNVVKLQVD 305
            .:.::....|:.   ||||.:.|:|     ||...||       .|..|..::.....::|
plant  1099 EYFEAVEGVPKINDGYNPATWMLDV-----TTPSMESQMSLDFAQIFSNSSLYRRNQELIK---- 1154

  Fly   306 EETALIDVHKDALDLS---------HLRGKEQVGFWTQLSVLLRRHLRSMSRDMFAVQMRLVMHV 361
                         |||         :.:.|....|.||......:...|..|......:|.:|.|
plant  1155 -------------DLSTPPPGSKDVYFKTKYAQSFSTQTKACFWKQYWSYWRHPQYNAIRFLMTV 1206

  Fly   362 VVALLLGVVYWQIG---GDAQKIVSNVSCLFFVILFVFAGNA---MPSILLCMQDSAVFIREYYN 420
            |:.:|.|:::||||   .:.|.:.:....::..:||:.|.||   .|:|.:   :..||.||...
plant  1207 VIGVLFGLIFWQIGTKTENEQDLNNFFGAMYAAVLFLGALNAATVQPAIAI---ERTVFYREKAA 1268

  Fly   421 GWYSLGAYYLSKVLADLPLQLTCPTMFISIGYFMTGQPPEFQRFAMC-WALC--------VMTAF 476
            |.||...|.:|:|..::........::..|.|.|.|          | |.:.        ::|:|
plant  1269 GMYSAIPYAISQVAVEIMYNTIQTGVYTLILYSMIG----------CNWTMAKFLWFYYYMLTSF 1323

  Fly   477 IGHFIGVIAGSLFTMQLAIFLVPSATIP------FL----LFSGFFIRLNEL----SWF--LRPI 525
            | :|      :|:.|.| :.|.|:..|.      ||    |||||.|...::    .|:  ..|:
plant  1324 I-YF------TLYGMML-MALTPNYQIAGICMSFFLSLWNLFSGFLIPRPQIPIWWRWYYWATPV 1380

  Fly   526 CDVSFFRYIFEGLMRAIYGYDR---------GELECYATSNFCYYRTAEQFLKDFQMEGNEFDWD 581
            .      :...||:.:..| |:         |:::                ||....||..|:.|
plant  1381 A------WTLYGLITSQVG-DKDSMVHISGIGDID----------------LKTLLKEGFGFEHD 1422

  Fly   582 ----MAVLGIFLILLLLAFF 597
                :||:.|..|||.|..|
plant  1423 FLPVVAVVHIAWILLFLFVF 1442

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9664	NP_722889.1	ABCG_EPDR	20..243	CDD:213180	80/240 (33%)
		EcfA2	23..247	CDD:224047	80/241 (33%)
		ABC2_membrane	338..539	CDD:279410	57/231 (25%)
		YadH	<388..547	CDD:223912	46/186 (25%)
ABCG39	NP_176867.2	PLN03140	14..1454	CDD:215599	180/670 (27%)
		ABC_trans_N	94..169	CDD:291196
		P-loop_NTPase	180..430	CDD:304359
		ABC2_membrane	531..737	CDD:279410
		PDR_assoc	744..810	CDD:285559
		ABCG_PDR_domain2	850..1088	CDD:213199	79/237 (33%)
		ABC2_membrane	1183..1388	CDD:279410	57/231 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X52
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910