DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9664 and PEN3

DIOPT Version :9

Sequence 1:	NP_722889.1	Gene:	CG9664 / 33540	FlyBaseID:	FBgn0031515	Length:	609	Species:	Drosophila melanogaster
Sequence 2:	NP_176196.1	Gene:	PEN3 / 842281	AraportID:	AT1G59870	Length:	1469	Species:	Arabidopsis thaliana

Alignment Length:	664	Identity:	186/664 - (28%)
Similarity:	304/664 - (45%)	Gaps:	106/664 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 DNAVQAQPNGLGPQKQKA-----LELHFSQVSYSL--------KGATKGSTPIINEACGVFKSGR 54
            |:|.:|. .|.|.:|...     |.:.|..|.|.:        :|.|:....::....|.|:.|.
plant   843 DSAAEAS-GGAGNKKGMVLPFTPLAMSFDDVKYFVDMPGEMRDQGVTETRLQLLKGVTGAFRPGV 906

  Fly    55 LTAILGPSGAGKSTLLNALAGFKLQG-VTGQFLLNGRPRDIMSFRKMSAYIAQNFVMLNLLTVEE 118
            |||::|.|||||:||::.|||.|..| :.|...::|.|:...:|.::|.|..|..:....:||.|
plant   907 LTALMGVSGAGKTTLMDVLAGRKTGGYIEGDVRISGFPKVQETFARISGYCEQTDIHSPQVTVRE 971

  Fly   119 TLRVSTDLKMPSSTAAQEKQKIIDDIIDILQLQSCRRTL-----VKNLSGGEHKRLSIGIELVTN 178
            :|..|..|::|......||...:|.::::::|.|.|.::     |..||..:.|||:|.:|||.|
plant   972 SLIFSAFLRLPKEVGKDEKMMFVDQVMELVELDSLRDSIVGLPGVTGLSTEQRKRLTIAVELVAN 1036

  Fly   179 PPIMFFDEPTSGLDCVGSYQVICHLQRLAHDGRIVVCVVHQPGSRLFQLFDDVLVLAH-GEVLYA 242
            |.|:|.||||||||...:..|:..::.....||.|||.:|||...:|:.||:::::.. |:|:||
plant  1037 PSIIFMDEPTSGLDARAAAIVMRAVRNTVDTGRTVVCTIHQPSIDIFEAFDELMLMKRGGQVIYA 1101

  Fly   243 G----------EQREMLPTFAQSGHICPQYYNPADFALEVCS----------------QSSTTER 281
            |          |..|..|..::    .|:.||||.:.||..|                ||:..:|
plant  1102 GPLGQNSHKVVEYFESFPGVSK----IPEKYNPATWMLEASSLAAELKLSVDFAELYNQSALHQR 1162

  Fly   282 CESLITQNKMMHSTASNV-VKLQVDEETALIDVHKDALDLSHLRGKEQVGFWTQLSVLLRRHLRS 345
            .::|:.:..:..:.||:: ...|..:.|                       |.|....|.:...:
plant  1163 NKALVKELSVPPAGASDLYFATQFSQNT-----------------------WGQFKSCLWKQWWT 1204

  Fly   346 MSRDMFAVQMRLVMHVVVALLLGVVYWQIGG---DAQKIVSNVSCLFFVILFVFAGNAMPSILLC 407
            ..|......:|.:..:..:||:|.|:|||||   :|..:...:..|:..|:||...|......:.
plant  1205 YWRSPDYNLVRFIFTLATSLLIGTVFWQIGGNRSNAGDLTMVIGALYAAIIFVGINNCSTVQPMV 1269

  Fly   408 MQDSAVFIREYYNGWYSLGAYYLSKVLADLPLQLTCPTMFISIGYFMTGQPPEFQRFAMCWALCV 472
            ..:..||.||...|.||...|.:|:|..:||..|.....:..|.|.|.|...:.::|  .|.:
plant  1270 AVERTVFYRERAAGMYSAMPYAISQVTCELPYVLIQTVYYSLIVYAMVGFEWKAEKF--FWFV-- 1330

  Fly   473 MTAFIGHF-------IGVIAGSLFTMQLAIFLVPSATIP-FLLFSGFFIRLNEL-SWFL--RPIC 526
               |:.:|       .|::..||...|....:..||... |.|||||||...:: .|::  ..||
plant  1331 ---FVSYFSFLYWTYYGMMTVSLTPNQQVASIFASAFYGIFNLFSGFFIPRPKIPKWWIWYYWIC 1392

  Fly   527 DVSFFRYIFEGLMRAIYGYDRGELECYATSNFCYYRTAEQFLKDFQMEGNEFDWDM-AVLGIFLI 590
            .|::..|   ||:.:.||.....::....:...   |.:|:::|.....::|...: |||..|.:
plant  1393 PVAWTVY---GLIVSQYGDVETRIQVLGGAPDL---TVKQYIEDHYGFQSDFMGPVAAVLIAFTV 1451

  Fly   591 L--LLLAFFV-TLN 601
            .  .:.||.: |||
plant  1452 FFAFIFAFCIRTLN 1465

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9664	NP_722889.1	ABCG_EPDR	20..243	CDD:213180	82/242 (34%)
		EcfA2	23..247	CDD:224047	84/248 (34%)
		ABC2_membrane	338..539	CDD:279410	59/214 (28%)
		YadH	<388..547	CDD:223912	49/169 (29%)
PEN3	NP_176196.1	PLN03140	31..1469	CDD:215599	186/664 (28%)
		ABC_trans_N	89..165	CDD:291196
		ABCG_PDR_domain1	154..426	CDD:213200
		ABC2_membrane	527..733	CDD:279410
		PDR_assoc	740..800	CDD:285559
		ABCG_PDR_domain2	864..1102	CDD:213199	82/237 (35%)
		ABC2_membrane	1197..1404	CDD:279410	60/216 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X52
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910