DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9664 and ABCG10

DIOPT Version :9

Sequence 1:	NP_722889.1	Gene:	CG9664 / 33540	FlyBaseID:	FBgn0031515	Length:	609	Species:	Drosophila melanogaster
Sequence 2:	NP_175734.1	Gene:	ABCG10 / 841761	AraportID:	AT1G53270	Length:	590	Species:	Arabidopsis thaliana

Alignment Length:	613	Identity:	160/613 - (26%)
Similarity:	286/613 - (46%)	Gaps:	87/613 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 QVSYSLKGATK-------GSTPIINEACGVF----------------KSGRLTAILGPSGAGKST 68
            ::||.|:  ||       |:||..:..||:.                :|..:|||.|||||||:|
plant    14 EISYRLE--TKNLSYRIGGNTPKFSNLCGLLSEKEEKVILKDVSCDARSAEITAIAGPSGAGKTT 76

  Fly    69 LLNALAGFKLQG-VTGQFLLNGRPRDIMSFRKMSAYIAQNFVMLNLLTVEETLRVSTDLKMPS-- 130
            ||..|||....| |:||.|:||||.|...:|::|.::.|...:...|||:|||..|..|::.:
plant    77 LLEILAGKVSHGKVSGQVLVNGRPMDGPEYRRVSGFVPQEDALFPFLTVQETLTYSALLRLKTKR 141

  Fly   131 -STAAQEKQKI----IDDIIDILQLQSCRRTLVKNLSGGEHKRLSIGIELVTNPPIMFFDEPTSG 190
             ..||:.|:.|    ::.:.|....|..|    ..:||||.:|:|||:|||.:|.::..||||||
plant   142 KDAAAKVKRLIQELGLEHVADSRIGQGSR----SGISGGERRRVSIGVELVHDPNVILIDEPTSG 202

  Fly   191 LDCVGSYQVICHLQRLA-HDGRIVVCVVHQPGSRLFQLFDDVLVLAHGEVLYAGEQREMLPTFAQ 254
            ||...:.||:..|:.:. ..|:.:|..:||||.|:.:..|.:::|::|.|:..|....:......
plant   203 LDSASALQVVTLLKDMTIKQGKTIVLTIHQPGFRILEQIDRIVLLSNGMVVQNGSVYSLHQKIKF 267

  Fly   255 SGHICPQYYNPADFALEVCS--QSSTTERCESLITQNKMMHSTASNVVKLQVDEETALIDVHKDA 317
            |||..|:..|..::|:::..  :...|:.|..:....   ||.......:....|....|.|.::
plant   268 SGHQIPRRVNVLEYAIDIAGSLEPIRTQSCREISCYG---HSKTWKSCYISAGGELHQSDSHSNS 329

  Fly   318 LDLSHLRGKEQVGFWTQLSVLLRRHLRSMSRDMFAVQMRLVMHVVVALLLGVVYWQIGGDAQKI- 381
            :             ..::.:|.:|..:::.|.......|.:...:..|:||.:|..:|...::.
plant   330 V-------------LEEVQILGQRSCKNIFRTKQLFTTRALQASIAGLILGSIYLNVGNQKKEAK 381

  Fly   382 VSNVSCLFFVILFVFAGNAMPSILLCMQDSAVFIREYYNGWYSLGAYYLSKVLADLPLQLTCPTM 446
            |.......|::.|:.: :....:.:.:||..:.:||.....|.:.:|.|:..|..:|..|....:
plant   382 VLRTGFFAFILTFLLS-STTEGLPIFLQDRRILMRETSRRAYRVLSYVLADTLIFIPFLLIISML 445

  Fly   447 FISIGYFMTGQPPEFQRF----AMCWALCVMT-AFIGHFIGVIAGSLFTMQLAIFLVPSATIPFL 506
            |.:..|::.|...|...|    .:.|.:.:|: :|:..|..::...:....:...|:.|    |.
plant   446 FATPVYWLVGLRRELDGFLYFSLVIWIVLLMSNSFVACFSALVPNFIMGTSVISGLMGS----FF 506

  Fly   507 LFSGFFIRLNELSWFLRPICDVSFFRYIFEGLMRAIYGYDRGELECYATSNFCYYRTAEQFLKDF 571
            ||||:||..:.:..:...:..:|.|:|.||.||...|   ||::                |||..
plant   507 LFSGYFIAKDRIPVYWEFMHYLSLFKYPFECLMINEY---RGDV----------------FLKQQ 552

  Fly   572 QMEGNEFDWDMAVLGIFLI-LLLLAFFV 598
            .::.::...::.::..|:: ..:|.||:
plant   553 DLKESQKWSNLGIMASFIVGYRVLGFFI 580

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9664	NP_722889.1	ABCG_EPDR	20..243	CDD:213180	89/247 (36%)
		EcfA2	23..247	CDD:224047	90/251 (36%)
		ABC2_membrane	338..539	CDD:279410	45/206 (22%)
		YadH	<388..547	CDD:223912	38/163 (23%)
ABCG10	NP_175734.1	3a01204	27..589	CDD:273361	155/598 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	121	1.000	Domainoid score	I1855
eggNOG	1	0.900	-	-		E2759_KOG0061
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1022017at2759
OrthoFinder	1	1.000	-	-		FOG0000053
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR48041
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.920