DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9664 and ABCG23

DIOPT Version :9

Sequence 1:	NP_722889.1	Gene:	CG9664 / 33540	FlyBaseID:	FBgn0031515	Length:	609	Species:	Drosophila melanogaster
Sequence 2:	NP_197442.2	Gene:	ABCG23 / 832061	AraportID:	AT5G19410	Length:	633	Species:	Arabidopsis thaliana

Alignment Length:	597	Identity:	162/597 - (27%)
Similarity:	280/597 - (46%)	Gaps:	64/597 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 LHFSQVSYSLKGATKGSTPIINEACGVFKSGRLTAILGPSGAGKSTLLNALAG---FKLQGVTGQ 84
            |..:.:||::     ..|||:|......:|.::.|::||||.||||||..::|   .|....:..
plant    61 LTVTNLSYTI-----NHTPILNSVSLAAESSKILAVVGPSGTGKSTLLKIISGRVNHKALDPSSA 120

  Fly    85 FLLNGRP-RDIMSFRKMSAYIAQNFVMLNLLTVEETLRVSTDLKMPSSTAAQEKQKIIDDIIDIL 148
            .|:|.|. .|....|::..::.|:..:|.||||:|||..|....:..|| |:|:::.::.::..|
plant   121 VLMNNRKITDYNQLRRLCGFVPQDDDLLPLLTVKETLMYSAKFSLRDST-AKEREERVESLLSDL 184

  Fly   149 QLQSCRRTLV-------KNLSGGEHKRLSIGIELVTNPPIMFFDEPTSGLDCVGSYQVICHLQRL 206
            .|...:.:.|       :.:||||.||:||.:|::.:|||:..||||||||...|.||:..|..:
plant   185 GLVLVQDSFVGEGDEEDRGVSGGERKRVSIAVEMIRDPPILLLDEPTSGLDSRNSLQVVELLATM 249

  Fly   207 AHD-GRIVVCVVHQPGSRLFQLFDDVLVLAHGEVLYAGEQREMLPTFAQSGHICPQYYNPADFAL 270
            |.. .|.|:..:|||..|:.....|.|:|:.|.|::.|....:..:.|:.|...|:..||.:||:
plant   250 AKSKQRTVLFSIHQPSYRILDYISDYLILSRGSVIHLGSLEHLEDSIAKLGFQIPEQLNPIEFAM 314

  Fly   271 EVCSQSSTTE-RCESLITQNKMMHSTASNVVKLQVDEETALIDVHKDALDLSHLRGKEQVGFWTQ 334
            |:.....|.: ...:::..:.|......|...:...|...::||                   |:
plant   315 EIVESLRTFKPNSVAVVESSSMWPENNENDGIISKKEAFRVLDV-------------------TE 360

  Fly   335 LSVLLRRHLRSMSRDMFAVQMRLVMHVVVALLLGVVYWQIGGDAQKIVSNVSCLFFVILFVFAG- 398
            :|.|..|..:.:.|.......|.:..||..|.||.||.::..|.:.:...:....|.:.|:.:.
plant   361 ISYLCSRFCKIIYRTKQLFLARTMQAVVAGLGLGSVYTRLKRDEEGVAERLGLFAFSLSFLLSST 425

  Fly   399 -NAMPSILLCMQDSAVFIREYYNGWYSLGAYYLSKVLADLPLQLTCPTMFISIGYFMTGQPPEFQ 462
             .|:|   :.:::..|.::|...|.|.:.:|.::..:|.:|.......:|....|::.|..|..|
plant   426 VEALP---IYLRERRVLMKESSRGSYRISSYMIANTIAFVPFLFVVSLLFSIPVYWIVGLNPSIQ 487

  Fly   463 RFA---MC-WALCVMTAFIGHFIGVIAGSLFTMQLAIFLVPSATIPFLLFSGFFIRLNEL--SWF 521
            .|:   :| |.:.:|.:.:..|:..::....:....|..|..|   |.||||:||...::  .|.
plant   488 AFSFFVLCVWLIILMASSLVLFLSAVSPDFISGNSLICTVLGA---FFLFSGYFIPKEKIPKPWM 549

  Fly   522 LRPICDVSFFRYIFEGLMRAIYGYDRGELECYATSNFCYYRTAEQFLKDFQMEGNEFDWDMAVLG 586
            .  :..||.:||..|.::  :..|.....||:::.|.....|.|..||:   .|.:.|.....:|
plant   550 F--MYYVSLYRYPLESMV--VNEYWSMREECFSSGNMGCLMTGEDVLKE---RGLDKDTRWINVG 607

  Fly   587 IFLILLLLAFFV 598
            |     :|||||
plant   608 I-----MLAFFV 614

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9664	NP_722889.1	ABCG_EPDR	20..243	CDD:213180	79/231 (34%)
		EcfA2	23..247	CDD:224047	80/235 (34%)
		ABC2_membrane	338..539	CDD:279410	49/208 (24%)
		YadH	<388..547	CDD:223912	38/166 (23%)
ABCG23	NP_197442.2	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0061
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1022017at2759
OrthoFinder	1	1.000	-	-		FOG0000053
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR48041
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.920