DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9664 and ABCG1

DIOPT Version :9

Sequence 1:	NP_722889.1	Gene:	CG9664 / 33540	FlyBaseID:	FBgn0031515	Length:	609	Species:	Drosophila melanogaster
Sequence 2:	NP_181467.1	Gene:	ABCG1 / 818520	AraportID:	AT2G39350	Length:	740	Species:	Arabidopsis thaliana

Alignment Length:	595	Identity:	150/595 - (25%)
Similarity:	275/595 - (46%)	Gaps:	87/595 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 QVSYSLKGATKGSTPIINEACGVFKSGRLTAILGPSGAGKSTLLNALAGFKLQG-VTGQFLLNGR 90
            :::.:.:..||   .::|...|..:.|.:.|:||.||:|||||::|||....:| :.|...|||.
plant    97 EIAQTARPKTK---TLLNNISGETRDGEIMAVLGASGSGKSTLIDALANRIAKGSLKGTVKLNGE 158

  Fly    91 PRDIMSFRKMSAYIAQNFVMLNLLTVEETLRVSTDLKMPSSTAAQEKQKIIDDIIDILQLQSCRR 155
            .......:.:|||:.|:.::..:|||||||..:.:.::|.|....:|:..:..:||.|.:::..:
plant   159 TLQSRMLKVISAYVMQDDLLFPMLTVEETLMFAAEFRLPRSLPKSKKKLRVQALIDQLGIRNAAK 223

  Fly   156 TLV-----KNLSGGEHKRLSIGIELVTNPPIMFFDEPTSGLDCVGSYQVICHLQRLAHDGRIVVC 215
            |::     :.:||||.:|:||||:::.:|.::|.||||||||...::.|:..|:|:|..|.||:.
plant   224 TIIGDEGHRGISGGERRRVSIGIDIIHDPILLFLDEPTSGLDSTSAFMVVKVLKRIAQSGSIVIM 288

  Fly   216 VVHQPGSRLFQLFDDVLVLAHGEVLYAGEQREMLPTFAQSGHICPQYYNPADFALEVCSQ-SSTT 279
            .:|||..|:..|.|.::.|:.|..:|:|....:...|.:.|...|:..|..:|||::..: ..:.
plant   289 SIHQPSHRVLGLLDRLIFLSRGHTVYSGSPASLPRFFTEFGSPIPENENRTEFALDLIRELEGSA 353

  Fly   280 ERCESLITQNKMMHSTASNVVKLQVDEETALID--------VHKDALDLSHLRGK-----EQVG- 330
            .....||..||....     :|.|.:.:..|..        ..|:|:..|..|||     |.|.
plant   354 GGTRGLIEFNKKWQE-----MKKQSNRQPPLTPPSSPYPNLTLKEAIAASISRGKLVSGGESVAH 413

  Fly   331 ------------------FWTQLSVLLRRHLRSMSRDMFAVQMRLVMHVVVALLLGVVYWQIGGD 377
                              .|.::..|.:|.:.:..|......:|:...|:...:|..|:|::...
plant   414 GGATTNTTTLAVPAFANPMWIEIKTLSKRSMLNSRRQPELFGIRIASVVITGFILATVFWRLDNS 478

  Fly   378 AQKIVSNVSCLFFVI--LFVFAGNAMPSILLCMQDSAVFIREYYNGWYSLGAYYLSKVLADLPLQ 440
            .:.:...:....|.:  :|....:|:|..|   |:..:|:||.....|...:|.||..:...|..
plant   479 PKGVQERLGFFAFAMSTMFYTCADALPVFL---QERYIFMRETAYNAYRRSSYVLSHAIVSFPSL 540

  Fly   441 LTCPTMFISIGYF-------MTGQPPEFQRFAMCWALCVMTAFI--GHFIGVIAGSLFTMQLAIF 496
            :.....|.:..|:       :||        .:.:.|.::.:|.  ..|:..::|.:.::.|...
plant   541 IFLSVAFAATTYWAVGLDGGLTG--------LLFYCLIILASFWSGSSFVTFLSGVVPSVMLGYT 597

  Fly   497 LVPSATIPFLLFSGFFIRLNELS----WFLRPICDVSFFRYIFEGLMRAIYGYDRGELECYATSN 557
            :|.:....|||||||||..|.:.    ||..    :|..:|.:|.:::          ..::.:.
plant   598 IVVAILAYFLLFSGFFINRNRIPDYWIWFHY----MSLVKYPYEAVLQ----------NEFSDAT 648

  Fly   558 FCYYRTAEQF 567
            .|:.|..:.|
plant   649 KCFVRGVQIF 658

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9664	NP_722889.1	ABCG_EPDR	20..243	CDD:213180	76/221 (34%)
		EcfA2	23..247	CDD:224047	77/225 (34%)
		ABC2_membrane	338..539	CDD:279410	47/215 (22%)
		YadH	<388..547	CDD:223912	39/173 (23%)
ABCG1	NP_181467.1	3a01204	106..739	CDD:273361	150/586 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0061
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1022017at2759
OrthoFinder	1	1.000	-	-		FOG0000053
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR48041
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.920