DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9664 and ABCG31

DIOPT Version :9

Sequence 1:	NP_722889.1	Gene:	CG9664 / 33540	FlyBaseID:	FBgn0031515	Length:	609	Species:	Drosophila melanogaster
Sequence 2:	NP_180555.2	Gene:	ABCG31 / 817544	AraportID:	AT2G29940	Length:	1426	Species:	Arabidopsis thaliana

Alignment Length:	659	Identity:	183/659 - (27%)
Similarity:	311/659 - (47%)	Gaps:	101/659 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 DNAVQAQPNGLGPQKQ------KALELHFSQVSYSL--------KGATKGSTPIINEACGVFKSG 53
            :.|:.|..|.:..:|:      |.|.:.|..|:|.:        :|..:....:::...|||..|
plant   800 ETALVADANQVISEKKGMILPFKPLTMTFHNVNYYVDMPKEMRSQGVPETRLQLLSNVSGVFSPG 864

  Fly    54 RLTAILGPSGAGKSTLLNALAGFKLQGVT-GQFLLNGRPRDIMSFRKMSAYIAQNFVMLNLLTVE 117
            .|||::|.|||||:||::.|||.|..|.| |...::|.|::..:|.::|.|:.||.:....:|||
plant   865 VLTALVGSSGAGKTTLMDVLAGRKTGGYTEGDIRISGHPKEQQTFARISGYVEQNDIHSPQVTVE 929

  Fly   118 ETLRVSTDLKMPSSTAAQEKQKIIDDIIDILQLQSCRRTLV-----KNLSGGEHKRLSIGIELVT 177
            |:|..|..|::|.....::|::.::.::.:::|.:.|..||     ..||..:.|||:|.:|||.
plant   930 ESLWFSASLRLPKEITKEQKKEFVEQVMRLVELDTLRYALVGLPGTTGLSTEQRKRLTIAVELVA 994

  Fly   178 NPPIMFFDEPTSGLDCVGSYQVICHLQRLAHDGRIVVCVVHQPGSRLFQLFDDVLVLAH-GEVLY 241
            ||.|:|.||||||||...:..|:..::.....||.|||.:|||...:|:.||::|::.. |:|:|
plant   995 NPSIIFMDEPTSGLDARAAAIVMRTVRNTVDTGRTVVCTIHQPSIDIFEAFDELLLMKRGGQVIY 1059

  Fly   242 AGE---QREMLPTFAQSGHICPQY---YNPADFALEVCSQSSTTERCE--------SLITQNKMM 292
            .|:   ..::|..:.|..:..|..   ||||.:.|||     ||...|        .|..::...
plant  1060 GGKLGTHSQVLVDYFQGINGVPPISSGYNPATWMLEV-----TTPALEEKYNMEFADLYKKSDQF 1119

  Fly   293 HSTASNVVKLQVDEETALIDVHKDALDLSHLRGKEQVGFWT-----QLSVLL----RRHL---RS 345
            ....:|:.:|.|..|                 |.|.:.|.:     |||..|    :::|   ||
plant  1120 REVEANIKQLSVPPE-----------------GSEPISFTSRYSQNQLSQFLLCLWKQNLVYWRS 1167

  Fly   346 MSRDMFAVQMRLVMHVVVALLLGVVYWQIGG---DAQKIVSNVSCLFFVILFVFAGNAMPSILLC 407
            ...::    :|||...:.|.:||.|:|.||.   .:|.:::.:..|:...||:...||.....:.
plant  1168 PEYNL----VRLVFTTIAAFILGTVFWDIGSKRTSSQDLITVMGALYSACLFLGVSNASSVQPIV 1228

  Fly   408 MQDSAVFIREYYNGWYSLGAYYLSKVLADLPLQLTCPTMFISIGYFMTGQPPEFQRFAMCWALCV 472
            ..:..||.||...|.|:...|..::.|.::|..||...::..|.||..|....|.:|.:......
plant  1229 SIERTVFYREKAAGMYAPIPYAAAQGLVEIPYILTQTILYGVITYFTIGFERTFSKFVLYLVFMF 1293

  Fly   473 MTAFIGHFIGVIAGSLFTMQLAIFLVPSATIPFLLFSGFFIRLNELSWFL--RPICDV--SFFRY 533
            :|.....|.|:         :|:.|.|:..:..::.|.|:...|.||.||  :|:..|  .:|.|
plant  1294 LTFTYFTFYGM---------MAVGLTPNQHLAAVISSAFYSLWNLLSGFLVQKPLIPVWWIWFYY 1349

  Fly   534 I------FEGLMRAIYGYDRGELECYATSNFCYYRTAEQFLK-DFQMEGNEFDWDMAVLGIFLIL 591
            |      .:|::.:    ..|::|....... ::.|.::|:: .|..:.|......|||..|..|
plant  1350 ICPVAWTLQGVILS----QLGDVESMINEPL-FHGTVKEFIEYYFGYKPNMIGVSAAVLVGFCAL 1409

  Fly   592 LLLAFFVTL 600
            ...||.:::
plant  1410 FFSAFALSV 1418

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9664	NP_722889.1	ABCG_EPDR	20..243	CDD:213180	84/237 (35%)
		EcfA2	23..247	CDD:224047	84/241 (35%)
		ABC2_membrane	338..539	CDD:279410	56/220 (25%)
		YadH	<388..547	CDD:223912	41/168 (24%)
ABCG31	NP_180555.2	PLN03140	17..1426	CDD:215599	183/659 (28%)
		ABC_trans_N	77..151	CDD:291196
		ABCG_PDR_domain1	155..416	CDD:213200
		ABC2_membrane	517..723	CDD:279410
		PDR_assoc	730..793	CDD:285559
		ABCG_PDR_domain2	823..1061	CDD:213199	84/237 (35%)
		ABC2_membrane	1156..1361	CDD:279410	55/217 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X52
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.910