DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9664 and ABCG7

DIOPT Version :9

Sequence 1:	NP_722889.1	Gene:	CG9664 / 33540	FlyBaseID:	FBgn0031515	Length:	609	Species:	Drosophila melanogaster
Sequence 2:	NP_849922.1	Gene:	ABCG7 / 814660	AraportID:	AT2G01320	Length:	728	Species:	Arabidopsis thaliana

Alignment Length:	616	Identity:	176/616 - (28%)
Similarity:	303/616 - (49%)	Gaps:	50/616 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 GPQKQKALELHFSQVSYSLKG-ATKGSTPIINEACGVFKSGRLTAILGPSGAGKSTLLNALAG-F 76
            |....:.:.:.:..::.||.. ::|....::....|..|.|||.||:||||:||:||||.||| .
plant    61 GGDSIRPVTIRWRNITCSLSDKSSKSVRFLLKNVSGEAKPGRLLAIMGPSGSGKTTLLNVLAGQL 125

  Fly    77 KLQ---GVTGQFLLNGRPRDIMSFRKMSAYIAQNFVMLNLLTVEETLRVSTDLKMPSSTAAQEKQ 138
            .|.   .::|...:||:|....:::  .|::.|..:..:.|||.|||..:.:|::|..::|:|:.
plant   126 SLSPRLHLSGLLEVNGKPSSSKAYK--LAFVRQEDLFFSQLTVRETLSFAAELQLPEISSAEERD 188

  Fly   139 KIIDDIIDILQLQSCRRTL-----VKNLSGGEHKRLSIGIELVTNPPIMFFDEPTSGLDCVGSYQ 198
            :.:::::..|.|.||..:.     |:.:||||.||||:..||:.:|.::|.||||:|||...:.:
plant   189 EYVNNLLLKLGLVSCADSCVGDAKVRGISGGEKKRLSLACELIASPSVIFADEPTTGLDAFQAEK 253

  Fly   199 VICHLQRLAHDGRIVVCVVHQPGSRLFQLFDDVLVLAHGEVLYAGEQ-REMLPTFAQSGHICPQY 262
            |:..||:||.||..|:|.:|||...::..|||:::|..|.::|||.. :|.|..|...|.:||::
plant   254 VMETLQKLAQDGHTVICSIHQPRGSVYAKFDDIVLLTEGTLVYAGPAGKEPLTYFGNFGFLCPEH 318

  Fly   263 YNPADFALEVCS---QSSTT-----ERCESLITQNKMMHSTASNVVKLQVDEETALIDVHKDALD 319
            .|||:|..::.|   .||.|     :|..:|:.......|:......|.:.|||.
plant   319 VNPAEFLADLISVDYSSSETVYSSQKRVHALVDAFSQRSSSVLYATPLSMKEETK---------- 373

  Fly   320 LSHLRGKEQV------GFWTQLSVLLRRHLRSMSRDMFAVQMRLVMHVVVALLLGVVYWQIGGDA 378
             :.:|.:.:.      |:|.|..:||:|.....|||....::|..|.|..|::.|.|:|::|...
plant   374 -NGMRPRRKAIVERTDGWWRQFFLLLKRAWMQASRDGPTNKVRARMSVASAVIFGSVFWRMGKSQ 437

  Fly   379 QKIVSNVSCLFFVILFVFAGNAMPSILLCMQDSAVFIREYYNGWYSLGAYYLSKVLADLPLQLTC 443
            ..|...:..|....:.........::.:..::.|:..||...|.||||.|.|||.:|::|:....
plant   438 TSIQDRMGLLQVAAINTAMAALTKTVGVFPKERAIVDRERSKGSYSLGPYLLSKTIAEIPIGAAF 502

  Fly   444 PTMFISIGYFMTGQPPEFQRFAMCWALCVMTAFIGHFIGVIAGSLF-TMQLAIFLVPSATIPFLL 507
            |.||.::.|.|....|...||.....:..:.:|....:|:..|::. :.:.|:.:.||....|::
plant   503 PLMFGAVLYPMARLNPTLSRFGKFCGIVTVESFAASAMGLTVGAMVPSTEAAMAVGPSLMTVFIV 567

  Fly   508 FSGFFIRLNELSWFLRPICDVSFFRYIFEGL-MRAIYG--YDRGELECYATSNFCYYRTAEQFLK 569
            |.|:::..:......|.|...|..|:.|:|| :....|  :|.        .|....:|.||.|:
plant   568 FGGYYVNADNTPIIFRWIPRASLIRWAFQGLCINEFSGLKFDH--------QNTFDVQTGEQALE 624

  Fly   570 DFQMEGNEFDWDMAVLGIFLILLLLAFFVTL 600
            .....|......:|.....|:....|.::.|
plant   625 RLSFGGRRIRETIAAQSRILMFWYSATYLLL 655

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9664	NP_722889.1	ABCG_EPDR	20..243	CDD:213180	82/232 (35%)
		EcfA2	23..247	CDD:224047	84/234 (36%)
		ABC2_membrane	338..539	CDD:279410	54/202 (27%)
		YadH	<388..547	CDD:223912	40/162 (25%)
ABCG7	NP_849922.1	ABCG_EPDR	67..298	CDD:213180	82/232 (35%)
		3a01204	90..655	CDD:273361	171/585 (29%)
		ABC2_membrane	397..601	CDD:279410	54/203 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0061
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1022017at2759
OrthoFinder	1	1.000	-	-		FOG0000053
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X52
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.820