DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9664 and abcg5

DIOPT Version :9

Sequence 1:	NP_722889.1	Gene:	CG9664 / 33540	FlyBaseID:	FBgn0031515	Length:	609	Species:	Drosophila melanogaster
Sequence 2:	NP_001122162.1	Gene:	abcg5 / 557317	ZFINID:	ZDB-GENE-050517-40	Length:	652	Species:	Danio rerio

Alignment Length:	656	Identity:	169/656 - (25%)
Similarity:	294/656 - (44%)	Gaps:	117/656 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 LHFSQVSYSLKGAT-----------KGSTPIINEACGVFKSGRLTAILGPSGAGKSTLLNALAG- 75
            |....||||:....           |.:..|:||......||::..|||.||:||:|||:|:||
Zfish    42 LSVKNVSYSVSERVGPWWDLSSFRKKWTRQILNEVSFHLDSGQIMGILGNSGSGKTTLLDAIAGR 106

  Fly    76 ----FKLQGVTGQFLLNGRPRDIMSFRKMSAYIAQNFVMLNLLTVEETLRVSTDLKMPSSTAAQE 136
                ..||   |:..:|||......|:...:|:.|:..:|:.|||||||..:..|.:...:|...
Zfish   107 IGNSGNLQ---GEVFVNGRKLKREQFQDCFSYVLQSDNLLSYLTVEETLTYTAQLALRKHSAEAI 168

  Fly   137 KQKIIDDIIDILQLQSCRRTLV-----KNLSGGEHKRLSIGIELVTNPPIMFFDEPTSGLDCVGS 196
            ::| :..::..|.|.....:::     ..:||||.:|:||..:|:.:|.::..||||:|||.:.:
Zfish   169 RKK-VTAVMAELSLGHVAHSVIGGRVFPGISGGERRRVSIASQLLQDPKVILLDEPTTGLDSMTA 232

  Fly   197 YQVICHLQRLAHDGRIVVCVVHQPGSRLFQLFDDVLVLAHGEVLYAGEQREMLPTFAQSGHICPQ 261
            .|::..|..||...|||:..:|||.|.||::|:.:.:::.||:::.||..:|:..|:..|:.||:
Zfish   233 NQIVMLLAELARRDRIVIVTIHQPRSELFRIFNRIAIMSQGELVFCGEPHKMVDFFSSCGYECPE 297

  Fly   262 YYNPADFALEVCSQSSTTERC-ESLITQNKMMHSTASNVVKLQV---DEETALIDVHKDALDLSH 322
            |.||.|..:::   :|...|| |......:.||...|.....::   .:|.......:....:..
Zfish   298 YCNPFDIYVDL---TSVDTRCSEREAATYRRMHDITSAYQNSEIYTNMQEKIEQSCQRPDKPMIP 359

  Fly   323 LRGKEQVGFWTQLSVLLRRHLRSMSRDMFAVQMRLVMHVVVALL--------------------L 367
            .:.||.....::|.|||||..|::|||...:.|||..:::..|.                    :
Zfish   360 FKSKESPNCISKLGVLLRRTFRNVSRDRMGILMRLSQNLIYGLFIAFFLMRLGKDVTKGAVQDRI 424

  Fly   368 GVVYWQIGGDAQKIVSNVSCLFFVILFVFAGNAMPSILLCMQDSAVFIREYYNGWYSLGAYYLSK 432
            |::|..:|......:.|...||            |::      .|:..:|..:|.|.....:|:.
Zfish   425 GLIYQSMGASPYTGMLNAVALF------------PAL------RAISDQESKDGLYQKWQMFLAY 471

  Fly   433 VLADLPLQLTCPTMFISIGYFMTGQPPEFQRFAMCWALCVMTAFIGHFIGVIAGSLFTMQL---- 493
            ::..||..:....:|.|..|:..|..|:..|| :|::..||   :.|.|    |.|.|:.|
Zfish   472 IIHILPFSIISVFIFASFLYWTVGMNPDPVRF-LCFSAVVM---VPHII----GELLTLVLLGVV 528

  Fly   494 --------AIFLVPSATIPFLLFSGFFIRLNELSWFLRPICDVSFFRYIFEGL-MRAIYGYD--- 546
                    .:.|:..|.|  ::.|||.....::....:.:..::|.:|..|.| :...||.:
Zfish   529 QDPNMVNSGVALLNIAGI--MVGSGFLRGFKQMPVVFQWLSYLTFQKYGCELLIVTEFYGLNFTC 591

  Fly   547 ------RGELECYATSNFC-----YYRTAEQFLKDFQMEGNEFDWDMAVLGIFLILLLLAFFVTL 600
                  .|  ||...|...     |.....::.:||.:.       .|.|...:||.:::|.:.
Zfish   592 TPIAGLPG--ECLVDSGNMIIDQGYPGALSRYTQDFLLL-------YAFLPALVILGIISFKIR- 646

  Fly   601 NAVIRR 606
            :.::||
Zfish   647 DHLVRR 652

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9664	NP_722889.1	ABCG_EPDR	20..243	CDD:213180	78/240 (33%)
		EcfA2	23..247	CDD:224047	80/244 (33%)
		ABC2_membrane	338..539	CDD:279410	52/233 (22%)
		YadH	<388..547	CDD:223912	38/180 (21%)
abcg5	NP_001122162.1	3a01204	50..645	CDD:273361	163/638 (26%)
		ABCG_White	53..279	CDD:213201	73/229 (32%)
		ABC2_membrane	375..582	CDD:279410	52/234 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0061
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1022017at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.820