DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9664 and Abca4

DIOPT Version :9

Sequence 1:	NP_722889.1	Gene:	CG9664 / 33540	FlyBaseID:	FBgn0031515	Length:	609	Species:	Drosophila melanogaster
Sequence 2:	NP_001101191.1	Gene:	Abca4 / 310836	RGDID:	1309445	Length:	2290	Species:	Rattus norvegicus

Alignment Length:	314	Identity:	75/314 - (23%)
Similarity:	127/314 - (40%)	Gaps:	46/314 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    38 GSTPIINEACGVFKSGRLTAILGPSGAGKSTLLNALAGFKLQGVTGQFLLNGRPRDIM--SFRKM 100
            ||.|.::.....|...::||.||.:||||:|.|:.|.|. |...:|..|:.|:..:|.  :.|:.
  Rat   919 GSRPAVDRLNITFYENQITAFLGHNGAGKTTTLSILTGL-LPPTSGTVLIGGKDIEISLDAVRQS 982

  Fly   101 SAYIAQNFVMLNLLTVEETLRVSTDLKMPS-STAAQEKQKIIDDIIDILQLQSCRRTLVKNLSGG 164
            .....|:.::.:.|||.|.:.....||..| ..|..|.:.:::|    ..|...|....::||||
  Rat   983 LGMCPQHNILFHHLTVAEHILFYAQLKGRSWEEARLEMEAMLED----TGLHHKRNEEAQDLSGG 1043

  Fly   165 EHKRLSIGIELVTNPPIMFFDEPTSGLDCVGSYQVICHLQRLAHDGRIVVCVVHQPGSRLFQLFD 229
            ..::||:.|..|.:..::..||||||:|.. |.:.|..|......||.::...|.. .....|.|
  Rat  1044 MQRKLSVAIAFVGDSKVVVLDEPTSGVDPY-SRRSIWDLLLKYRSGRTIIMSTHHM-DEADLLGD 1106

  Fly   230 DVLVLAHGEVLYAGEQREMLPTFAQSGHI-------------------CPQYYNPADFALEVCSQ 275
            .:.:::.|.:..:|....:...|....::                   |.            |:.
  Rat  1107 RIAIISQGRLYCSGTPLFLKNCFGTGFYLTLVRKMKNIQSQRCGCEGACS------------CTS 1159

  Fly   276 SSTTERCESLITQNKMMHSTASNVVKLQVDEETALIDVHKDALDLSHLRGKEQV 329
            ...:.||.:.:.:     .|...|:...|.|.|.|:..|.....|....|:|.:
  Rat  1160 KGFSARCPARVDE-----ITEEQVLDGDVKELTDLVYHHVPEAKLVECIGQELI 1208

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9664	NP_722889.1	ABCG_EPDR	20..243	CDD:213180	59/207 (29%)
		EcfA2	23..247	CDD:224047	60/211 (28%)
		ABC2_membrane	338..539	CDD:279410
		YadH	<388..547	CDD:223912
Abca4	NP_001101191.1	rim_protein	1..2249	CDD:130324	75/314 (24%)
		ABC_subfamily_A	907..1126	CDD:213230	60/213 (28%)
		ABC_subfamily_A	1915..2135	CDD:213230
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000