DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9664 and Abcg3l1

DIOPT Version :9

Sequence 1:	NP_722889.1	Gene:	CG9664 / 33540	FlyBaseID:	FBgn0031515	Length:	609	Species:	Drosophila melanogaster
Sequence 2:	NP_001004076.2	Gene:	Abcg3l1 / 289453	RGDID:	1303294	Length:	646	Species:	Rattus norvegicus

Alignment Length:	670	Identity:	166/670 - (24%)
Similarity:	296/670 - (44%)	Gaps:	141/670 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 KALELHFSQVSYSLKGATKGSTPI---------INEACGVFKSGRLTAILGPSGAGKSTLLNALA 74
            |...|.|..:||  :...:...|:         ::...|:...| |.||:||....:|.||:.||
  Rat    33 KEAVLSFHNISY--RETVQSGFPLRQQTRVMERLSSISGIMGPG-LNAIMGPQDGSRSLLLDVLA 94

  Fly    75 GFKLQ-GVTGQFLLNGRPRDIMSFRKMSAYIAQNFVMLNLLTVEETLRVSTDLKMPSSTAAQEKQ 138
            ..:.. |::|..|:||:||. .:|:..|.||.||.|:|..:||.:.|..|..|::|.:....||:
  Rat    95 ARRDPCGLSGDILINGKPRP-ANFKCTSGYIPQNDVVLGTVTVRDNLEFSAALRLPMTVTRDEKR 158

  Fly   139 KIIDDIIDILQLQSCRRTLVKNLSGGEHKRLSIGIELVTNPPIMFFDEPTSGLDCVGSYQVICHL 203
            :.|::::::|.|:  :...||..|.|..||.||.:||||..||:|.|:||:|||...:..||..|
  Rat   159 RRINEVLELLHLE--KEQNVKPRSKGLRKRTSIAMELVTEHPILFLDDPTTGLDLRTTTDVISIL 221

  Fly   204 QRLAHDGRIVVCVVHQPGSRLFQLFDDVLVLAHGEVLYAGEQREMLPTFAQSGHICPQYYNPADF 268
            :|::..|:.::..::||...:|:.||.:.::|.|::::.|..|:.|..|..:|:....:.|||||
  Rat   222 RRMSMKGKTIIFSINQPQYSIFRFFDSLTLVASGKLMFHGPARDALEYFTSAGYQYESHNNPADF 286

  Fly   269 ALEVCS---------------------------------------QSSTTERCESLITQNKMMHS 294
            .|:|.:                                       .|:|..|.:.|:.:.|:..|
  Rat   287 FLDVINGGFPDTEEDGHEADENEEFVERQHQVTGKLANMYAQSPLHSATRARLDQLLGEQKLDRS 351

  Fly   295 TASNVVKLQVDEETALIDVHKDALDLSHLRGKEQVGFWTQLSVLLRRHLRSMSRDMFAVQMRLVM 359
            :|         .||..:                 ..||.||..:.||..::.....:...:::::
  Rat   352 SA---------VETTCV-----------------TPFWHQLGWITRRSFKNFLGFPWVTTIQVII 390

  Fly   360 HVVVALLLGVVYWQIGGDAQKIVSNVSCLFFVILFVFAGNAMPSIL---LCMQDSAVFIREYYNG 421
            .|::|:::|..:..:    |.:.:.:.....:||.:.....:.|:.   |.:.|...|:.|:.:|
  Rat   391 IVILAVVVGTAFRLL----QNVCTELQMRAILILLLTGFQCITSVTAGELFVIDQDRFLHEHTSG 451

  Fly   422 WYSLGAYYLSKVLADL-PLQLTCPTMFISIGYFMTGQPPEFQRFAMCWALCVMTAFIGHFIGVIA 485
            :|.:.:|:..|:||:| |.:|...|:|..|.||:.|.....:.|.......:|.|:....:.:..
  Rat   452 YYRVSSYFFGKLLAELIPRRLLPSTIFTLITYFIAGLRTSVRGFFTMTFTIMMLAYSASSLSLSL 516

  Fly   486 G------SLFTMQLAIFLVPSATIPFLLF-------SGFFIRLNELSWFLRPICDVSFFRYIFEG 537
            |      ::.|:.:.|:.|      |:||       :||   |..|||       :.:|.....|
  Rat   517 GAGENVAAITTLLVTIYFV------FMLFFSGLSLDTGF---LPVLSW-------IRYFSIPHYG 565

  Fly   538 LMRAIYGYDRGELECYATSNFC-YYR-------------TAEQFL--KDFQMEGNEFDWDMAVLG 586
            ....::....|:       ||| .|.             |.|:||  :.|.:....|..:...|.
  Rat   566 FRALLHNEFLGQ-------NFCPEYNTEEVSRCQNYVICTGEEFLEIQGFHLSSWGFWENHLALA 623

  Fly   587 IFLILLLLAFFVTLNAVIRR 606
            ..:|:||...:|.|..:.:|
  Rat   624 CTMIILLTITYVQLLLLKKR 643

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9664	NP_722889.1	ABCG_EPDR	20..243	CDD:213180	76/232 (33%)
		EcfA2	23..247	CDD:224047	77/233 (33%)
		ABC2_membrane	338..539	CDD:279410	46/217 (21%)
		YadH	<388..547	CDD:223912	40/175 (23%)
Abcg3l1	NP_001004076.2	P-loop_NTPase	35..261	CDD:304359	76/231 (33%)
		3a01204	64..644	CDD:273361	160/637 (25%)
		ABC2_membrane	369..572	CDD:279410	46/222 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0061
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1022017at2759
OrthoFinder	1	1.000	-	-		FOG0000053
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X52
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.820