DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9664 and Abca2

DIOPT Version :9

Sequence 1:	NP_722889.1	Gene:	CG9664 / 33540	FlyBaseID:	FBgn0031515	Length:	609	Species:	Drosophila melanogaster
Sequence 2:	XP_006497672.1	Gene:	Abca2 / 11305	MGIID:	99606	Length:	2464	Species:	Mus musculus

Alignment Length:	305	Identity:	80/305 - (26%)
Similarity:	129/305 - (42%)	Gaps:	53/305 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    54 RLTAILGPSGAGKSTLLNALAGFKLQGVTGQFLLNGRPRDIMS----FRKMSAYIAQNFVMLNLL 114
            ::.:.||.:||||:|.::.|.|. ....:|...:.|  .||.:    .||......|:.|:.:.|
Mouse  1048 QVVSFLGHNGAGKTTTMSILTGL-FPPTSGSATIYG--HDIRTEMDEIRKNLGMCPQHNVLFDRL 1109

  Fly   115 TVEETLRVSTDLKMPSSTAAQEKQKIIDDIIDILQLQSCRRTLVKNLSGGEHKRLSIGIELVTNP 179
            ||||.|...:.||   |.|.:|.:|..|.:|:.|:|.:.|.:||:.||||..::||:.|..|...
Mouse  1110 TVEEHLWFYSRLK---SMAQEEIRKETDKMIEDLELSNKRHSLVQTLSGGMKRKLSVAIAFVGGS 1171

  Fly   180 PIMFFDEPTSGLDCVGSYQVICHLQRLAHDGRIVVCVVHQPGSRLFQLFDDVLVLAHGEV----- 239
            ..:..||||:|:|.. :.:.|..|......||.::...|.. .....|.|.:.:::||::
Mouse  1172 RAIILDEPTAGVDPY-ARRAIWDLILKYKPGRTILLSTHHM-DEADLLGDRIAIISHGKLKCCGS 1234

  Fly   240 ------LYAGEQREML------------PTFAQSGHICPQYYNPADFALEVCSQSSTTERCESLI 286
                  .|....|..|            |..|.|...||:        |..||:...::.....:
Mouse  1235 PLFLKGAYGDGYRLTLVKQPAEPGTSQEPGLASSPSGCPR--------LSSCSEPQVSQFIRKHV 1291

  Fly   287 TQNKMMHSTA--------SNVVKLQVDEETALIDVHKDALDLSHL 323
            ..:.::..|:        |..||....|.  |....:.:||..||
Mouse  1292 ASSLLVSDTSTELSYILPSEAVKKGAFER--LFQQLEHSLDALHL 1334

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9664	NP_722889.1	ABCG_EPDR	20..243	CDD:213180	60/203 (30%)
		EcfA2	23..247	CDD:224047	60/207 (29%)
		ABC2_membrane	338..539	CDD:279410
		YadH	<388..547	CDD:223912
Abca2	XP_006497672.1	rim_protein	58..2398	CDD:130324	80/305 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000