DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9664 and abcg4

DIOPT Version :9

Sequence 1:	NP_722889.1	Gene:	CG9664 / 33540	FlyBaseID:	FBgn0031515	Length:	609	Species:	Drosophila melanogaster
Sequence 2:	XP_004916110.1	Gene:	abcg4 / 101734071	XenbaseID:	XB-GENE-22063023	Length:	639	Species:	Xenopus tropicalis

Alignment Length:	599	Identity:	230/599 - (38%)
Similarity:	352/599 - (58%)	Gaps:	36/599 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 KQKALELHFSQVSYSLKGA----TKGSTPIINEACGVFKSGRLTAILGPSGAGKSTLLNALAGFK 77
            |:.|:::.|..:|||::..    .:|...::....|:|.|..|..|:||||||||||:|.|||::
Frog    51 KRSAVDIEFKDLSYSVREGPCWRKRGYKTLLKCLSGMFCSRELIGIMGPSGAGKSTLMNILAGYR 115

  Fly    78 LQGVTGQFLLNGRPRDIMSFRKMSAYIAQNFVMLNLLTVEETLRVSTDLKMPSSTAAQEKQKIID 142
            ..|:|||.|:||:.|::.:|||||.||.|:.::|..|||:|.:.|||:||:  :...:.|:|:::
Frog   116 ESGMTGQILVNGKQRELRTFRKMSCYIMQDDMLLPHLTVKEAMMVSTNLKL--NEKMEVKKKLVN 178

  Fly   143 DIIDILQLQSCRRTLVKNLSGGEHKRLSIGIELVTNPPIMFFDEPTSGLDCVGSYQVICHLQRLA 207
            :|:..|.|..|..|....||||:.|||:|.:|||.|||:|||||||||||....:||:..|..||
Frog   179 EILTALGLLDCSGTRTLFLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLLNSLA 243

  Fly   208 HDGRIVVCVVHQPGSRLFQLFDDVLVLAHGEVLYAGEQREMLPTFAQSGHICPQYYNPADFALEV 272
            ..||.::|.:|||.::||::|:.:.:|:.|:.:|.|....::|.....|..||.|:|||||.:|:
Frog   244 QGGRTIICTIHQPSAKLFEMFNKLYILSQGQCIYRGSVTHLIPYLKGLGLHCPTYHNPADFIIEL 308

  Fly   273 CS-----------QSSTTERCESLITQNKMMHSTASNVVKLQVDEETALIDVHKDALDLSHLRGK 326
            .|           ::.....|.  ||::|      |...||..:.....:.||.:    ||....
Frog   309 ASGEYGDLNPLLFRAVEDGLCP--ITRDK------SQQTKLDQEHCPNDVSVHVE----SHTFAT 361

  Fly   327 EQVGFWTQLSVLLRRHLRSMSRDMFAVQMRLVMHVVVALLLGVVYWQIGGDAQKIVSNVSCLFFV 391
            ..:   .|..:|.:|...|:.||.....:|.:.|:.:.:|:|::|..||.||.|:.:|...|||.
Frog   362 SSL---NQFCILFKRTFLSILRDTVLTHLRFMSHLCIGVLIGLLYLHIGDDASKVFNNTGFLFFS 423

  Fly   392 ILFVFAGNAMPSILLCMQDSAVFIREYYNGWYSLGAYYLSKVLADLPLQLTCPTMFISIGYFMTG 456
            :||:.....||::|....:.:||:||:.|.||||.||||:|.:||:|.|:.||..:.||.|:||.
Frog   424 MLFLMFAALMPTVLTFPLEMSVFLREHLNYWYSLKAYYLAKTMADVPFQIVCPVAYCSIVYWMTS 488

  Fly   457 QPPEFQRFAMCWALCVMTAFIGHFIGVIAG-SLFTMQLAIFLVPSATIPFLLFSGFFIRLNELSW 520
            ||||..||.:..||...||.:...:|::.| :..::|:|.|:.|...||.|||||||:....:..
Frog   489 QPPEVSRFLLFSALATSTALVAQSLGLLIGVASNSLQVATFVGPVTAIPVLLFSGFFVSFKTIPT 553

  Fly   521 FLRPICDVSFFRYIFEGLMRAIYGYDRGELECYATSNFCYYRTAEQFLKDFQMEGNEFDWDMAVL 585
            :|:....:|:.||.|||::.||||.||..|:|....  |.::..:|.|::..:|..:...|..||
Frog   554 YLQWCSYISYVRYGFEGVILAIYGMDRAPLQCRELP--CTFQLPQQVLQELDVEDAKLYVDFLVL 616

  Fly   586 -GIFLILLLLAFFV 598
             |.||.|.|||:.|
Frog   617 GGFFLGLRLLAYLV 630

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9664	NP_722889.1	ABCG_EPDR	20..243	CDD:213180	100/226 (44%)
		EcfA2	23..247	CDD:224047	100/227 (44%)
		ABC2_membrane	338..539	CDD:279410	81/201 (40%)
		YadH	<388..547	CDD:223912	69/159 (43%)
abcg4	XP_004916110.1	3a01204	40..639	CDD:273361	230/599 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D177791at33208
OrthoFinder	1	1.000	-	-		FOG0000053
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR48041
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X52
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	6.020