Protein Alignment OtopLb and otop1

DIOPT Version :9

• Sequence 1: NP_608758.1
• Gene: OtopLb / 33539
• FlyBaseID: FBgn0031514
• Length: 797
• Species: Drosophila melanogaster
• Sequence 2: NP_942098.1
• Gene: otop1 / 322893
• ZFINID: ZDB-GENE-030131-1613
• Length: 586
• Species: Danio rerio
• Alignment Length: 691
• Identity: 144/691 - (20%)
• Similarity: 246/691 - (35%)
• Gaps: 229/691 - (33%)

  Fly   204 SGATSARNGSTAFFDNGAKSFQ------AKQQKDKNRRTGNDAISSALSATYCKLLVLLGVCL-- 260
            :.|:||.:.|::..:|  |.|.      .|:...||        :..|||.|...|:||||.:
Zfish    18 AAASSASSSSSSDAEN--KLFSRLKVSLTKKYPQKN--------AELLSAQYGTNLLLLGVSVML 72

  Fly   261 -------PITE--VISDQIPTYVYQGFYVYLYVGSILFVIFLYISAFRNRSLFNALKDYHEKNSN 316
                   |:.|  ::|          |...|.:..:::::...|...|.||
Zfish    73 ALAAQSGPVKEEHLLS----------FITVLMLVQLVWMLCYMIRRERERS-------------- 113

  Fly   317 VHLKHKVTHFGSFYLRVGAIAFAIGTMVYSGLEFGQFFELNGHPGCRDVFVAITPICRMVLCIAQ 381
             .:..:..|.|:.::|.|....|:.:::......|.|.   |:..|....:.:.||...:..|:|
Zfish   114 -PVPERDAHAGASWIRGGLTMLALLSLIMDAFRIGYFV---GYHSCISAALGVYPIVHALHTISQ 174

  Fly   382 VQFIFLNTTYMDMARHKVTSRFGLMHMVATNLCEWLYVLVEETKHEIFHISQHEVDPAHDLVIHN 446
            |.|::.:...: :.:::...|||::|.|.|||..|...::.||:|
Zfish   175 VHFLWFHIKDV-IKKYETFERFGVIHAVFTNLLLWCNGVMSETEH-------------------- 218

  Fly   447 SSMSRTDWAAVNESLHQHHHHHALNNTLVANVSSVIVNMTITPSPTPAAFSGCSRTTIMGALVQQ 511
                           ..|:|...|.....||:|:|.|.            ..|:.||.:..:...
Zfish   219 ---------------FMHNHRRRLIEMGYANLSTVDVQ------------PHCNCTTSVWLMFST 256

  Fly   512 LSPFLFPCTIEYSLICAVILFEMWKTVKSIPDIDKTRKNSVKPAAAKPAHHFSVDCSQSHKGLFF 576
            ...:|:|..|||.:..:.:||.|||.:....|....||..                |....||..
Zfish   257 SLYYLYPFNIEYHIFVSAMLFVMWKNIGRTLDRHSNRKRR----------------STGSTGLLL 305

  Fly   577 GILIIVMTIISMIMYFVLYTQPGYELVATQEVTLWETFMYFMCAAAVI--------TGMILMRDL 633
            |.|..::.:.|.:...|:|.   ..|..|:|:......|::....|::        ||:::.|
Zfish   306 GPLGGLVALASSVSVLVVYL---IHLEKTEEMHEAAVSMFYYYGVAMMACMCVGSGTGLLVYR-- 365

  Fly   634 RYIKNTSDEHHSMD--------LDNLLLIVAQTGVYLYGMFSILGSYFAKWDTVPD-RVEGIIAE 689
                   .|:..||        ||..||:.:..|.:|....|::.|........|. ....:...
Zfish   366 -------MENRPMDTGSNPARTLDTELLLASSLGSWLMSWCSVVASVAEAGQKSPSFSWTSLTYS 423

  Fly   690 VFGVVQTSLQTMFILHSSHRR----------------------------------------CRGT 714
            :..|::..:|.:||:.|.:||                                        ..|:
Zfish   424 LLLVLEKCIQNLFIVESLYRRHSEEEEDAAAPQVFSVAVPPYDGILNHGYEAHDKHREAEPAAGS 488

  Fly   715 NQVRRK---------------PGRE------IITFLLVANIAIWFV----------NTLIKGRAV 748
            :.:.||               |||:      |..||.:.||::|.:          |.|
Zfish   489 HALSRKQPDAPLPAGQRLDVTPGRKRQILKNICMFLFMCNISLWILPAFGCRPQYDNPL------ 547

  Fly   749 FRESHLEFFGVWGWTIITHISMPLAIFYRFHSTICLFEVWK 789
                ..|.||...||.:.::::||.:|||.||...||||::
Zfish   548 ----ENETFGTSVWTTVLNVAIPLNLFYRMHSVASLFEVFR 584

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
OtopLb	NP_608758.1	Otopetrin	330..778	CDD:281218	107/535 (20%)
otop1	NP_942098.1	Otopetrin	127..572	CDD:281218	106/533 (20%)
		FYR-box	163..167		2/3 (67%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	484..505		3/20 (15%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	131	1.000	Inparanoid score	I4607
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D243107at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm6364
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR21522
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X278
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	6.070