Protein Alignment OtopLb and otpl-3

DIOPT Version :10

• Sequence 1: NP_608758.1
• Gene: OtopLb / 33539
• FlyBaseID: FBgn0031514
• Length: 797
• Species: Drosophila melanogaster
• Sequence 2: NP_509170.1
• Gene: otpl-3 / 259710
• WormBaseID: WBGene00017449
• Length: 566
• Species: Caenorhabditis elegans
• Alignment Length: 643
• Identity: 163/643 - (25%)
• Similarity: 272/643 - (42%)
• Gaps: 138/643 - (21%)

  Fly   196 STATINFQSGATSARNGSTAFFDNGAKSFQAKQQKDKNRRTGNDAISSA-----LSATYCKLLVL 255
            |.||..|.....::.|.||....|....|:..::    |...:||.|.|     .:..|...:|:
 Worm     2 SKATEEFDLIDRTSSNCSTIATPNSKVRFRYHEK----RYWLSDAWSRAYVFRLFTCFYAIFIVI 62

  Fly   256 LGVCLPITEVISDQIPTYVYQG--------FYVYLYVGSILFVIF-------LYISAFRNR-SLF 304
            .|:.:.::.:|:.:..|    |        ...:|..|||||:.:       ::.:..|.| ||
 Worm    63 AGIVIELSNIIAAEENT----GKISIKDLVLGTWLLGGSILFIAYCSYLVHDMHFTIKRQRISL- 122

  Fly   305 NALKDYHEKNSNVHLKHKV----THFGSFYLRVGAIAFAIGTMVYSGLEF-----GQFFELNGHP 360
                    :||.:......    |..||.|||:|.:.|.|..:||..|.|     |    .:.:.
 Worm   123 --------RNSGISATEPEVLANTSTGSLYLRLGCVVFGIIGVVYYLLIFVICLLG----WSSNE 175

  Fly   361 GCRDVFVAITPICRMVLCIAQVQFIFLNTTYMDMARHKVTSRFGLMHMVATNLCEWL-YVLVE-- 422
            |...|...:..:...|....|:.|::.|...:......: :||||||:..|||..|| |:|.|
 Worm   176 GECSVISDVLNVMAAVFIFVQMWFVYCNGKIIFTGDGNL-ARFGLMHLTGTNLWMWLRYILYEEV 239

  Fly   423 ETKHEIFHISQHEVDPAHDLVIHNSSMSRTDWAAVNESLHQHHHHHALNNTLVANVSSVIVNMTI 487
            ||..||.|: ||            :::|:..           .|||.::......|..:
 Worm   240 ETVKEIRHV-QH------------ANLSKAS-----------AHHHEVHEEACKGVLCI------ 274

  Fly   488 TPSPTPAAFSGCSRTTIMGALVQQLSPFLFPCTIEYSLICAVILFEMWKTVKSIPDID---KTRK 549
                    |:|             .:.|::.|.:|||||||.:.|..|..::.:....   |.:|
 Worm   275 --------FNG-------------YNEFMYTCVVEYSLICAGVAFVFWANLERLKREQMEKKMKK 318

  Fly   550 NSVKPAAAKPAHHFSVDCSQSHKGLFFGILIIVMTIISMIMYFVLYTQPGYELVATQEVTLW--- 611
            .|:          ..:|||::.:|||.|...|::|||: |..|..|:       :.:.|..|
 Worm   319 RSI----------LKIDCSRTAEGLFAGFACIIVTIIA-IALFNAYS-------SDKNVAQWIFS 365

  Fly   612 -ETFMYFMCAA-AVITGMILMRDLRYIKNTSDEH--HSMDLDNLLLIVAQTGVYLYGMFSILGSY 672
             ....:|:.:. .|:.....||.|:::....||.  ::..||.:||:|...|..::.:..||.
 Worm   366 CTNMSFFLVSTFLVVFAFWRMRYLKFLMEDDDEEDDNAELLDRILLVVGLIGELIFSIGGILS-- 428

  Fly   673 FAKWDTVPDRVEGIIAEVFGVVQTSLQTMFILHSSHRRCRGTNQ--VRRKPGREIITFLLVANIA 735
            |....|:...:......|..::|.:.|:..::.:|..|...:||  :|.|||:::||.||:.|.|
 Worm   429 FINNMTIGLPLIIFTTNVLRLIQVTFQSCLLMVASRLRIEESNQHMLRYKPGKQVITMLLMMNCA 493

  Fly   736 IWFVNTLIKGRAVFRESHLEFFGVWGWTIITHISMPLAIFYRFHSTICLFEVWKITYK 793
            .:.:|.....:|...:..:..:|.:.|.|:.....||.|||||||:.|..|:||.|::
 Worm   494 QFMMNVFEAQKAGINDEMIHMYGSYYWAIVVRGCSPLTIFYRFHSSACFAEIWKKTFR 551

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
OtopLb	NP_608758.1	Otopetrin	330..778	CDD:460840	119/467 (25%)
otpl-3	NP_509170.1	Otopetrin	144..536	CDD:460840	119/467 (25%)