Protein Alignment OtopLb and Otop2

DIOPT Version :9

• Sequence 1: NP_608758.1
• Gene: OtopLb / 33539
• FlyBaseID: FBgn0031514
• Length: 797
• Species: Drosophila melanogaster
• Sequence 2: NP_001349329.1
• Gene: Otop2 / 237987
• MGIID: 2388365
• Length: 563
• Species: Mus musculus
• Alignment Length: 628
• Identity: 135/628 - (21%)
• Similarity: 239/628 - (38%)
• Gaps: 193/628 - (30%)

  Fly   254 VLLGVCLPITEVISDQIPTYVYQGFYVYLYVGSILFVIFLYISAFRNRSLFNALKDYHEKNSNVH 318
            |||..|..|:....:::..|...   |:..:.:::.:..|:|       :|..|:.....::
Mouse    39 VLLLACTLISGGAFNKVAVYDTD---VFALLTTMMLLAALWI-------VFYLLRTARCPDA--- 90

  Fly   319 LKHKVTHFGSFYLRVGAIAFAIGTMVYSGLEFG---QFFELNGHPGCRDVFVAITPICRMVLCIA 380
            :.::..|.|..:||.|.:.|.|.|:|....:.|   .|||      |:.....:.||.:.|..|.
Mouse    91 VPYRDAHAGPIWLRGGLVLFGICTLVMDVFKTGYYSSFFE------CQSAIKILHPIIQAVFVIV 149

  Fly   381 QVQFIFLNT-----TYMDMARHKVTSRFGLMHMVATNLCEWLYVLVEETKHEIFHISQHEVDPAH 440
            |..|::::.     |::|:      :|.|||..:||||..|:..:|:|:.|:     .|....:|
Mouse   150 QTYFLWISAKDCIHTHLDL------TRCGLMFTLATNLAIWMAAVVDESVHQ-----AHSYSGSH 203

  Fly   441 DLVIH---NSSMSRTDWAAVNESLHQHHHHHALNNTLVANVSSVIVNMTITPSPTPAAFSGCSRT 502
            ....|   |....|...||..:.                                      |..:
Mouse   204 GNTSHTRLNPDSKRAGGAAEEDP--------------------------------------CLCS 230

  Fly   503 TIMGALVQQLSPFLFPCTIEYSLICAVILFEMWKTVKSIPDIDKTRKNSVKPAAAKPAHHFSVDC 567
            |.:..:.||...:|:|..|||||..:.:|:.|||.|..:  :..|..:...|:      ..|:..
Mouse   231 TAICQIFQQGYFYLYPFNIEYSLFASTMLYVMWKNVGRL--LASTHGHGHTPS------RVSLFR 287

  Fly   568 SQSHKGLFFGILIIVMTIISMIMYFVLYT-QPGYELVATQEVTLWETFMYFMCAAAV----ITGM 627
            .....|...|:|:.|:.:...|:|.|..: :.|:   ..|.:.::.:| ..:|...:    ::|.
Mouse   288 ETFFAGPVLGLLLFVVGLAVFILYEVQVSGERGH---TRQALVIYYSF-NIVCLGLMTLVSLSGS 348

  Fly   628 ILMR-DLRYIKNTSDEHH---SMDLDNLLLIVAQTGVYLYGMFSI----LGSYFAKWDTVPDRVE 684
            ::.| |.|.:     :||   :..||..||:.|..|.|....:||    :||        |..::
Mouse   349 VIYRFDRRAM-----DHHKNPTRTLDVALLMGAALGQYAISYYSIVAVVVGS--------PRDLQ 400

  Fly   685 GII---AEVFGVVQTSLQTMFILHSSHR--------------RCRG-----TNQVRRKPG----- 722
            |.:   ..:..:.|.:.|.:||:.|.||              .|:|     .:.:|..|.
Mouse   401 GALNLSHALLMIAQHTFQNVFIIESLHRGPPGAEPREMPPKEPCQGITFANLDAIRTLPSCPPTP 465

  Fly   723 -----------------------------REIITFLLVANIAIW----------FVNTLIKGRAV 748
                                         ::|..|||:.|:.:|          |.||:
Mouse   466 RLVIPNLESPQEAVAIISAPRCHWRRRCLKDISLFLLLCNVILWIMPAFGARPHFSNTV------ 524

  Fly   749 FRESHLEFFGVWGWTIITHISMPLAIFYRFHSTICLFEVWKIT 791
                .::|:|...|..|.:|.:|..||||.|:...|.||:.::
Mouse   525 ----EVDFYGYSLWAAIVNICLPFGIFYRMHAVSSLLEVYVLS 563

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
OtopLb	NP_608758.1	Otopetrin	330..778	CDD:281218	117/537 (22%)
Otop2	NP_001349329.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..20
		Otopetrin	103..549	CDD:397346	116/535 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4740
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	170	1.000	Inparanoid score	I4117
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D243107at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8758
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR21522
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X278
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	9	8.930