Protein Alignment OtopLb and otpl-6

DIOPT Version :10

• Sequence 1: NP_608758.1
• Gene: OtopLb / 33539
• FlyBaseID: FBgn0031514
• Length: 797
• Species: Drosophila melanogaster
• Sequence 2: NP_505195.1
• Gene: otpl-6 / 185807
• WormBaseID: WBGene00018479
• Length: 581
• Species: Caenorhabditis elegans
• Alignment Length: 635
• Identity: 152/635 - (23%)
• Similarity: 273/635 - (42%)
• Gaps: 109/635 - (17%)

  Fly   188 NLQGTASGSTATINFQSGATSARNGSTAFFDNGAKSFQAKQQKDKNRRTGNDAISSALSATYCKL 252
            :::.|:|..|...::.|  |...|......:..|:||..|                :|:|.|..:
 Worm    12 SIESTSSDVTVLTDYSS--TIPENLPAWTKNTKAQSFGLK----------------SLTALYTLI 58

  Fly   253 LVLLGVCLPITEVISDQIPTYVYQGFYVYLYVGSILFVIFLYISAFRNRSLFNALKDYHEKNS-- 315
            |.::...:.|:.....:.....|..|.|.:|..:||:.|:|| :......:||.:..|.|:..
 Worm    59 LTIVAFIIEISPTWQSESMNIEYTIFCVLMYSIAILYFIYLY-AYILYPIVFNTILLYLERMRVL 122

  Fly   316 NVHLKHKVTH---------FGSFYLRVGAIAF-AIGTMVYSGLEFGQFFELNGHPGCRDVFVAIT 370
            |||...:...         .|:.|||:|.:.| .:|::::....|..||....|    :::| :.
 Worm   123 NVHTVKRWVQPEPVFTGEGAGTLYLRLGTVLFGTLGSVLWGCEIFLCFFTETRH----NIYV-VK 182

  Fly   371 PICRMVLCIAQVQFIFLNTTYMDMARHKVTSRFGLMHMVATNLCEW----LYVLVEETKHEIFHI 431
            .|...:....|:.|:..|:. :|:.::...:.||:||.||.||..|    |...|.::..:...:
 Worm   183 YILAFLFTYLQMHFLCCNSK-IDLPKNNFLASFGMMHCVAVNLWVWFSLCLAKAVYKSDKKTLKL 246

  Fly   432 SQHEVDPAHDLVIHNSSMSRTDWAAVNESLHQHHHHHALNNTLVANVSSVIVNMTITPSPTPAAF 496
            .:.|..      ....:|:.|:               |:..|:...::|::      .|.:.:.|
 Worm   247 QKAEEK------YKKKNMTITE---------------AVAETITTTIASIV------SSESSSGF 284

  Fly   497 SGCSRTTIMGALVQQLSPFLFPCTIEYSLICAVILFEMWKTVKSIPDIDKTRKNSVKPAAAKPAH 561
            ....:.......:...:.||....:|:|||.|.:.|.:||........|..:|
 Worm   285 RADEKQLRSLYKLGSAANFLLTTMVEFSLIAAAVYFIVWKHEGEQTPQDARKK------------ 337

  Fly   562 HFSVDCSQSHKGLFFGILIIVMTIISMIMYFVLYTQPGYELVATQEVTLWETFMYFMCAAAVITG 626
            |...||..:..|:|..|::::.:.||:.|::: |........|.:.:.:.||.::.:|..||...
 Worm   338 HVRFDCKSTSVGIFAAIVLLIGSFISIAMHYI-YNNSDMPRTADEVIGIAETVLFCVCLLAVFGA 401

  Fly   627 MILMRDLRYIKNTSDEHHSMDLDNLLLIVAQTGVYLY---GMFSILGSYFAKWDTVPDRVEG--- 685
            .|.||.|:|..:.    |...:|.:||||...|..:|   |:...|..          |:|.
 Worm   402 FIRMRKLQYRLHA----HGQVVDEILLIVGLAGEIVYCSTGLDLYLNG----------RLENTPG 452

  Fly   686 -----IIAEVFGVVQTSLQTMFILHSSHRRCRGTNQVRRKPGREIITFLLVANIAIWFVNTLIKG 745
                 ::|.|..:||..:|::|||.:|..|....:.:..:||::|:|||:|.||.::..:|....
 Worm   453 TSCLTVVAFVMRIVQVVVQSVFILVASRLRSLSASNISNQPGKQIVTFLVVCNINLFIYHTFETI 517

  Fly   746 RAVFRESHLEFFGVWGWTIITHISMPLAIFYRFHSTICLFEVWKITYKAK 795
            .:.|...| :...|  ::.:.:||.||.:||||||:.||.|:||..|..|
 Worm   518 ESNFGFPH-KMSSV--YSALLNISSPLVVFYRFHSSACLAEIWKHAYSKK 564

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
OtopLb	NP_608758.1	Otopetrin	330..778	CDD:460840	109/463 (24%)
otpl-6	NP_505195.1	Otopetrin	146..547	CDD:460840	109/463 (24%)