Protein Alignment OtopLb and otpl-5

DIOPT Version :9

• Sequence 1: NP_608758.1
• Gene: OtopLb / 33539
• FlyBaseID: FBgn0031514
• Length: 797
• Species: Drosophila melanogaster
• Sequence 2: NP_505196.2
• Gene: otpl-5 / 185806
• WormBaseID: WBGene00018478
• Length: 572
• Species: Caenorhabditis elegans
• Alignment Length: 621
• Identity: 153/621 - (24%)
• Similarity: 273/621 - (43%)
• Gaps: 103/621 - (16%)

  Fly   200 INFQSGATSARNGSTAFFDNGAKSFQAKQQKDKNRRTGNDAISSALSATYCKLLVLLGVCLPITE 264
            ::.:|.:||....::    :|..|.....|..||....|..: :.::|.|..:|:::...:.|:.
 Worm    15 VSMESTSTSVAMSTS----DGFSSHDDISQWTKNTDAKNFCV-NLMTAIYTLILIMVAFVIEISP 74

  Fly   265 VISDQIPTYVYQGFYVYLYVGSILFVIFLYISAFRNRSLFNALKDYHEKNSNVH---LKHKVTH- 325
            ....:.....|..|.|.:|..::.:.::||:... ..::.|:...|..|.:...   |...|.:
 Worm    75 TWRSEKMWLEYSIFCVLMYAVAVAYFLYLYLFVL-YPNVINSCIYYLFKKATPRRWLLDEPVFNG 138

  Fly   326 --FGSFYLRVGAIAF-AIGTMVYSGLEFGQFFELNGHPGCRDVFVAITPICRMVLCIAQVQFIFL 387
              .|:.||||||:.| ::|::::.......||:...|    .::| :..|..::....|:.|||.
 Worm   139 EGAGTMYLRVGALFFGSMGSVLWGTEILLCFFDNQRH----GIYV-VKYILAVIFTFMQMHFIFS 198

  Fly   388 NTTYMDMARHKVTSRFGLMHMVATNLCEWLYVLVEETKHEIFHISQHEVDPAHDLVIHNSSMSRT 452
            |:. :.:.|..:.::|||||.||.||..||.:.:  .|..|.| ::.|:
 Worm   199 NSK-ISLKRSNIIAKFGLMHSVAVNLWNWLSICL--IKSSIKH-AKKEI---------------- 243

  Fly   453 DWAAVNESLHQHHHHHALNNTLVANVSSVIVNMTITPSPTPAAFSGCSRTTIMGALVQQL----- 512
                      ::.:..:.|.|....::.:..:.|               |...|...:||
 Worm   244 ----------KYTYEGSDNETKTEILTEMSYDFT---------------TDSFGPHDKQLRAIIK 283

  Fly   513 ----SPFLFPCTIEYSLICAVILFEMWKTVKSIPDIDKTRKNSVKPAAAKPAHHFSVDCSQSHKG 573
                |..|..|.:|:|||.|||.|.:||...|         ||.:....|...||..|||.:..|
 Worm   284 LGSSSSILLTCLVEFSLIAAVICFIIWKNDDS---------NSGEALKKKKKRHFRFDCSGTTVG 339

  Fly   574 LFFGILIIVMTIISMIMYFVLYTQPGYELVATQEVTLWETFMYFMCAAAVITGMILMRDLRYIKN 638
            :|..:.:.:::.:::.|:.:| ::...:..|...|...:.|::.:...|.|.....||.|:|..:
 Worm   340 IFLAVAVHIISAVAVGMHGIL-SKSNRDSAANLLVGYTDVFLFVVALLACILAFFQMRKLQYRLH 403

  Fly   639 TSDEHHSMDLDNLLLIVAQTGVYLY---GMFSILGSYFAKWDTVPDRVEGIIAEVFGVVQTSLQT 700
            .    |...:|.:||||...|..:|   ||...:.....|   .|.....|::....:.:..:||
 Worm   404 A----HGEVIDEILLIVGLAGECVYSCAGMDLYINDKMIK---EPASYITIVSFTLRITEVLVQT 461

  Fly   701 MFILHSSHRRCRGTNQVRRKPGREIITFLLVANIAIWFVNTLIKGRAVFRESHLEF-FGVW---G 761
            :|||.::..||........:||:::||||||.||.::..:|       |..:.|.| |.:.   .
 Worm   462 IFILIATRMRCYTQTNCYTEPGKQVITFLLVCNINLFIYHT-------FETTELNFGFPIKLPDS 519

  Fly   762 WTIITHISMPLAIFYRFHSTICLFEVWKITYKAKAH 797
            ::.:.:|:.|:.:||||||:.||.|:||.||..|.|
 Worm   520 YSAMLNIASPIVVFYRFHSSACLAEIWKHTYSRKNH 555

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
OtopLb	NP_608758.1	Otopetrin	330..778	CDD:281218	115/464 (25%)
otpl-5	NP_505196.2	Otopetrin	145..536	CDD:281218	115/464 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	175	1.000	Domainoid score	I2171
eggNOG	1	0.900	-	-		E1_KOG4740
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG28576
OrthoDB	1	1.010	-	-		D243107at33208
OrthoFinder	1	1.000	-	-		FOG0001932
OrthoInspector	1	1.000	-	-		mtm4740
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR21522
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X278
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	11	10.890