Protein Alignment OtopLb and LOC1272199

DIOPT Version :10

• Sequence 1: NP_608758.1
• Gene: OtopLb / 33539
• FlyBaseID: FBgn0031514
• Length: 797
• Species: Drosophila melanogaster
• Sequence 2: XP_061511604.1
• Gene: LOC1272199 / 1272199
• VectorBaseID: AGAMI1_009667
• Length: 707
• Species: Anopheles gambiae
• Alignment Length: 777
• Identity: 172/777 - (22%)
• Similarity: 309/777 - (39%)
• Gaps: 187/777 - (24%)

  Fly   114 AKSQTNLDLVEHGSQRQALLPLPTVGMHHEDSACTLQVSRRPSLLLQEILTQRPPLFGRRDGNGF 178
            |.:|.:.|.:|..||....:.| ||....||.:.|  .:.|||         .|..:.:|..:.:
Mosquito    15 AITQRSNDSIEPASQSPGFITL-TVPSIVEDLSDT--DAARPS---------TPTTYQKRPASIY 67

  Fly   179 LSPRTAKNGNLQGTASGSTATINFQSGATSARNGST-AFFDNGAKSFQAKQQKDKNRRTGNDAIS 242
            .:          |.|......:::|   .|...||| |..|.........::|.|..|.   .::
Mosquito    68 ST----------GRAPPIIRAVSYQ---PSVAAGSTHASGDGHVPPPSTAEEKSKFTRR---YLA 116

  Fly   243 SALSATYCKLLVLLGVCLPITEVISDQIPTYVYQGFYVYLYVGSILFVIFLYI------------ 295
            .....:|...|::.|:...||:.:.:.....:.:.|.:|:....||:.:|||:
Mosquito   117 GVTGISYALFLIVFGLIAFITDAVENNARYPLAEVFALYMVAVGILYFVFLYVDIRVYVWRAQKA 181

  Fly   296 --SAFRNRSLF-----------------------NALKDYHEKNSNVHLKHK---VT--HFGSFY 330
              ...|.|.|:                       .|::...|..:...::|.   ||  |....|
Mosquito   182 LEELQRRRQLYAEQALAAESGTLGNGGGPLELSAAAVRPEWELPALKPIRHDYCFVTGRHGEIIY 246

  Fly   331 LRVGAIAFAIGTMVYSGLEFG-QFFELNGHPG----CRDVFVAITPICRMVLCIAQVQFIFLNTT 390
            |::||..|..|.:::|.|... |...:|...|    |.........:..:..|:..| |.|....
Mosquito   247 LKLGATWFCFGLLIHSVLLLSYQGILMNSRDGKWARCASNTTIAMEVLFLFYCLFLV-FFFWKYA 310

  Fly   391 YMDMARHKVTSRFGLMHMVATNLCEWLYVLVEETKHEIFHISQHEVDPAHDLVIHNSSMSRTDWA 455
            .:.:.|::..:|||:||.:.|.|..|:..:|.||...| .|.|...|.....|
Mosquito   311 NIVINRYRGLARFGIMHAIGTALAFWVLTIVRETVVAI-RIKQAYYDDGKPAV------------ 362

  Fly   456 AVNESLHQHHHHHALNNTLVANVSSVIVNMTITPSPTPAAFSGCSRTTIMGALVQQLSPFLFPCT 520
               |.....:.....:::::|.:.        .|.|..           :..::...||:|:|..
Mosquito   363 ---EEAAAAYEEPGRDSSMLAPID--------CPGPEE-----------LNQVLASFSPYLYPFV 405

  Fly   521 IEYSLICAVILFEMWKTVKSIPDIDKTRKNSVK----------PAAAKPA--------------- 560
            ||::::...:|:.::..:...|     :|.:||          .||:|..
Mosquito   406 IEFNILIVGLLYMIYANISKCP-----KKITVKGHRGHQAHGDGAASKAGGSVMDFDGKSECSDH 465

  Fly   561 ------HHFSV--------DCSQSHKGLFFGILIIVMTIISMIMYFVL-----YTQPGYELVATQ 606
                  |...|        ||..:.:|||.|::::|.||:.:|::.:.     |...|..|....
Mosquito   466 CNDTLDHEAQVKSRLVVYGDCQHASRGLFAGLILVVATIVVIILFHIAARDDDYRDTGILLDGIF 530

  Fly   607 EVTLWETFMYFMCAAAVITGMILMRDLRYIKNTS---DEHHSMDLDNLLLIVAQTGVYLYGMFSI 668
            |||:....::...||             |.:.|.   :.|....||::||.:|....:...:||:
Mosquito   531 EVTVLGIMIFATIAA-------------YYQTTRLDINPHPISRLDDVLLFIAIPAFFSESLFSM 582

  Fly   669 LGSYFAKWDTVPDRVEGIIAEVF-GVVQTSLQTMFILHSSHRRCRGTNQV-RRKPGREIITFLLV 731
            :.::     .....:.|.|  || .:.|..:||.:|. .:.|||..|.:: ::|||:|::||:.:
Mosquito   583 IPAF-----ENSSILNGFI--VFTQLAQILIQTPWIC-DALRRCSNTEELQQKKPGKELVTFMTI 639

  Fly   732 ANIAIWFVNTLIKGRAVFRESHLEFFGVWGWTIITHISMPLAIFYRFHSTICLFEVWKITYK 793
            ||:::|...|.......|.:...|::|...|:|:.|:|:||.:||||||::||.::|:.:|:
Mosquito   640 ANVSLWVYYTFSVKTGDFGDERYEYYGDVLWSILNHLSLPLIMFYRFHSSVCLVDIWRHSYE 701

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
OtopLb	NP_608758.1	Otopetrin	330..778	CDD:460840	114/501 (23%)
LOC1272199	XP_061511604.1	None