Protein Alignment OtopLb and LOC11175813

DIOPT Version :10

• Sequence 1: NP_608758.1
• Gene: OtopLb / 33539
• FlyBaseID: FBgn0031514
• Length: 797
• Species: Drosophila melanogaster
• Sequence 2: XP_061511152.1
• Gene: LOC11175813 / 11175813
• VectorBaseID: AGAMI1_006925
• Length: 664
• Species: Anopheles gambiae
• Alignment Length: 707
• Identity: 279/707 - (39%)
• Similarity: 384/707 - (54%)
• Gaps: 116/707 - (16%)

  Fly   155 PSLLLQEILTQRPPLFGR---RDGNGFLSPRTAKNGNLQGTASGSTATINFQSGATSARNGS--- 213
            |.|.:.....:|.|...|   ||.:...|.|.:.:.:.:||.........:.......|:||
Mosquito     4 PELRVHPPPDEREPAAARGSARDNSAASSARPSPHQSRRGTLDSVELVERYHFAKNPNRSGSHSP 68

  Fly   214 ----------------TAFFD---------NGAKSFQAKQQKD-----KNRRTGNDAISS----- 243
                            .||.:         :.|:.|.....|.     ::|:...|:|.:
Mosquito    69 SLYESRRRLSSFGAQKRAFLELIRKQGSRLSLARKFSEVSNKTDELSREHRKQQRDSILARNQLG 133

  Fly   244 -ALSATYCKLLVLLGVCLPITEVISDQIPTYVYQGFYVYLYVGSILFVIFLYISAFRNRSLFNAL 307
             ||||.|.|||:::|:.||:||:::.:.|...:|.||:|||..||||..||:::.:|..:....|
Mosquito   134 LALSALYAKLLIVMGITLPLTELVAREAPPNFHQPFYLYLYGVSILFCSFLFVARWRRAAQLEFL 198

  Fly   308 KD----YHEKNSNVHLKHKVT-HFGSFYLRVGAIAFAIGTMVYSGLEFGQFFELNGHPGCRDVFV 367
            ..    .....|....:...| |.||||||:|||||.||::|||.|:|||:|||:.|.|||:..|
Mosquito   199 SQCPAGADRSGSGGPARPAPTPHSGSFYLRIGAIAFGIGSLVYSALDFGQYFELDAHDGCRNFLV 263

  Fly   368 AITPICRMVLCIAQVQFIFLNTTYMDMARHKVTSRFGLMHMVATNLCEWLYVLVEETKHEIFHIS 432
            |:.|..||:||:.|:|||.::.....:|||...||||||||:|||:||||||||||.||||..|
Mosquito   264 ALLPAARMLLCVVQMQFIIVSGQDYGLARHAFVSRFGLMHMLATNVCEWLYVLVEEAKHEIVPI- 327

  Fly   433 QHEVDPAHDLVIHNSSMSRTDWAAVNESLHQHHH-----HHALNNTLVANVSSVIVNMTITPSPT 492
            .|.:.|           :|||        |:|||     .|.|.              ....|..
Mosquito   328 DHSLQP-----------NRTD--------HRHHHQDDPAQHRLG--------------WAAGSKE 359

  Fly   493 PAAFSGCSRTTIMGALVQQLSPFLFPCTIEYSLICAVILFEMWKTVKSIPDIDKTRKNSVKPAAA 557
            |     |..|.||..||...:|||||||||||||||:.|:|:|:.:..  .:..|.....||:.:
Mosquito   360 P-----CRSTHIMSTLVHNAAPFLFPCTIEYSLICALTLYELWRALNR--TLTATAAGPRKPSTS 417

  Fly   558 ---------KPAHHFSVDCSQSHKGLFFGILIIVMTIISMIMYFVLYTQPGYELVATQEVTLWET 613
                     :||:..|:|||.:.:|||.||:.:|:|:|.:||||||..:......||.|:..:|.
Mosquito   418 APDRRTVTGRPANRLSIDCSSAQRGLFGGIVTLVLTLIVLIMYFVLRREQHLRHAATLEIVAYEI 482

  Fly   614 FMYFMCAAAVITGMILMRDLRYIKNTSDEHHSMDLDNLLLIVAQTGVYLYGMFSILGSY-----F 673
            .:|.:...||:..|:.|||||.:.....: .:|.||..||:|.|||:|:||:|||:|:|     .
Mosquito   483 ALYSVTLGAVVAAMLRMRDLRVLAQRGSQ-RTMPLDCHLLLVTQTGIYIYGVFSIIGTYHTHGQL 546

  Fly   674 AKWDTVPDRVEGIIAEVFGVVQTSLQTMFILHSSHRRCRGTNQVRRKPGREIITFLLVANIAIWF 738
            ..|        .:::||..:.||||||:|:|.|..|||:|..|.|.||||:|:|||||||:|.|.
Mosquito   547 LHW--------AVLSEVLALAQTSLQTLFVLSSWWRRCKGARQNRTKPGRQIVTFLLVANLAAWM 603

  Fly   739 VNTLIKGRAVFRESHLEFFGVWGWTIITHISMPLAIFYRFHSTICLFEVWKITYKAK 795
            ||:|:|..|.||...:.|:|...|.||.||||||||||||||||||||:||.:|||:
Mosquito   604 VNSLVKSNASFRPLVMGFYGAGAWAIIAHISMPLAIFYRFHSTICLFEIWKNSYKAR 660

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
OtopLb	NP_608758.1	Otopetrin	330..778	CDD:460840	208/466 (45%)
LOC11175813	XP_061511152.1	None