Protein Alignment OtopLb and otop2

DIOPT Version :9

• Sequence 1: NP_608758.1
• Gene: OtopLb / 33539
• FlyBaseID: FBgn0031514
• Length: 797
• Species: Drosophila melanogaster
• Sequence 2: XP_017944835.2
• Gene: otop2 / 100496174
• XenbaseID: XB-GENE-6045877
• Length: 588
• Species: Xenopus tropicalis
• Alignment Length: 638
• Identity: 139/638 - (21%)
• Similarity: 230/638 - (36%)
• Gaps: 188/638 - (29%)

  Fly   235 RTGNDAISSALSATYCKLLVLLGVCLPITEVISD------QIPTYVYQGFYVYLYVGSILFVIFL 293
            :.|...:|..|...    :||||..|..:...:|      ::.:::    .|.:.:.||..|.:|
 Frog    58 KKGGRLLSGLLGIN----IVLLGCALVSSGAFTDVSVAEREVLSFL----SVLMGLSSIWMVSYL 114

  Fly   294 YISAFRNRSLFNALKDYHEKNSNVHLKHKVTHFGSFYLRVGAIAFAIGTMVYSGLEFGQFFELNG 358
                     |:.:...|:.|:|         |.|..:||.|.:.|.:.|:|...::.|:...|.
 Frog   115 ---------LWTSKHKYNLKDS---------HAGPIWLRGGLVLFGVCTLVLDVMKIGKSVTLI- 160

  Fly   359 HPGCRDVFVAITPICRMVLCIAQVQFIFLNTTYMDMAR-HKVTSRFGLMHMVATNLCEWLYVLVE 422
            |  |......:.|:.:.|..:.|..|::::.  .|.|: |...:|.|||..::|||..|:.
 Frog   161 H--CESPVKIVHPVIQGVFVVIQTYFLWVSC--KDCAQIHMNLTRCGLMITLSTNLAVWMA---- 217

  Fly   423 ETKHEIFHISQHEVDPAHDLVIHNSSMSRTDWAAVNESLHQHHHHHALNNTLVANVSSVIVNMTI 487
                                            |..:||||..|.   ||..:...||:     |:
 Frog   218 --------------------------------AVTDESLHLTHE---LNMDVNYTVSA-----TV 242

  Fly   488 TPSPTPAAFSGCSRTTIMGALVQQLSPFLFPCTIEYSLICAVILFEMWKTVKSIPDIDKTRKNSV 552
            .|........||...|.:....|....:|:|..|||||..:.:.:.|||.|..:
 Frog   243 GPRAAGGESHGCECATHVCKTFQNGYYYLYPFNIEYSLFASAMSYVMWKNVGRV----------- 296

  Fly   553 KPAAAKPAHHFSVDCSQSHK----GLFFGILIIVMTIISMIMYFVLY-TQPGYELVATQEVTLWE 612
                 ...||.:     .||    .||.|::..:...::.:..|::| .:...|...:|.:|::.
 Frog   297 -----MSGHHHT-----QHKFKTRNLFVGLICGIGVFVAGLGVFIVYKIEVDVEETRSQAITMFY 351

  Fly   613 TF---MYFMCAAAVITGMILMRDLRYIKNTSDEHH--SMDLDNLLLIVAQTGVYLYGMFSILGSY 672
            .|   ...:.:...:.|.|:   .|:.|...|.|.  :..||.:||:.|..|.|....|||:.
 Frog   352 IFNITALSLMSVVSLAGTII---YRFYKRDMDNHKNPTRTLDVVLLLGAALGQYCISFFSIVA-- 411

  Fly   673 FAKWDTVPDRVEG------IIAEVFGVVQTSLQTMFILHSSHRR--------------------- 710
                 .|..:..|      ::..:..:||.::|..||:...||:
 Frog   412 -----MVALQPGGQLHTLILVNALLLIVQHTIQNTFIIEGLHRQPHANSHPAADLQEKDQPPHVY 471

  Fly   711 -------------------------------------CRGTNQVRRKPGREIITFLLVANIAIWF 738
                                                 |...:..|||..:||..||||:||..|.
 Frog   472 INPAATVSHSDHSPSSHEKHEHELETKHHGTPTGFPECHSKSDWRRKALKEISLFLLVSNIIFWI 536

  Fly   739 VNTLIKGRAVFRESHLEFFGVWGWTIITHISMPLAIFYRFHSTICLFEVWKIT 791
            :..............|.|:| :.|..|.:|.:|..||||.|:...|.||:.:|
 Frog   537 MPAFGARPQFDNRLELNFYG-YTWVAIVNIGLPFGIFYRMHAIASLVEVYIMT 588

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
OtopLb	NP_608758.1	Otopetrin	330..778	CDD:281218	113/522 (22%)
otop2	XP_017944835.2	Otopetrin	134..574	CDD:397346	112/520 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	169	1.000	Inparanoid score	I4017
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D243107at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm9424
Panther	1	1.100	-	-	O	PTHR21522
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X278
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	6.070