Protein Alignment OtopLb and otop1.2

DIOPT Version :9

• Sequence 1: NP_608758.1
• Gene: OtopLb / 33539
• FlyBaseID: FBgn0031514
• Length: 797
• Species: Drosophila melanogaster
• Sequence 2: XP_031751200.1
• Gene: otop1.2 / 100494873
• XenbaseID: XB-GENE-22166276
• Length: 610
• Species: Xenopus tropicalis
• Alignment Length: 790
• Identity: 151/790 - (19%)
• Similarity: 261/790 - (33%)
• Gaps: 300/790 - (37%)

  Fly   113 LAKSQTNLDLVEHGSQRQAL-----LPLPTVGMHHEDSACTLQVSRRPSLLL---QEILTQRPPL 169
            :||.|..:|.|:   |.:.|     ||||                  |.|.|   ||||.:
 Frog     4 IAKMQNTVDSVQ---QEKGLGSLCDLPLP------------------PELELEVEQEILEE---- 43

  Fly   170 FGRRDGNGFLSPRTAKNGNLQGTASGSTATINFQSGATSARNGSTAFFDNGAKSFQAKQQKDKNR 234
                                          |...|...|::.|..||.
 Frog    44 ------------------------------IQKHSEIASSQYGINAFI----------------- 61

  Fly   235 RTGNDAISSALSATYCKLLVLLGVCLPITEVISDQIPTYVYQGFYVYLYVGSILFVIFLYISAFR 299
                           ..|.:||...|.:..|  ::|...:   |...|.:..:|:::: ||
 Frog    62 ---------------IGLFLLLACSLQVVGV--NEIDLKI---FVTILMLIQVLWMLW-YI---- 101

  Fly   300 NRSLFNALKDYHEKNSNVHLKHKVTHFGSFYLRVGAIAFAIGTMVYSGLEFGQFFELNGHPGCRD 364
               |.|:.|...:|..::|.       |:.:||.|...||:.|.....|:.|.|.   |:..|..
 Frog   102 ---LRNSTKKSGQKEKDLHA-------GARWLRCGISFFALTTTAMDALKLGYFI---GYRACMP 153

  Fly   365 VFVAITPICRMVLCIAQVQFIFLNTTYMDMAR-HKVTSRFGLMHMVATNLCEWLYVLVEETKHEI 428
            :...:.|:...:..:.||.|::.::  .|:.: :|...||||:|.|.|||..|...:..|:||:
 Frog   154 LTEGVYPVAHFIHTLFQVYFLWFHS--QDVIKSYKTLERFGLIHSVFTNLLLWASAVATESKHQ- 215

  Fly   429 FHISQHEVDPAHDLVIHNSSMSRTDWAAVNESLHQHHHHHALNNTLVANVSSVIVNMTITPSPTP 493
                         |..|...:|...:  ||.|:.:                       |||.
 Frog   216 -------------LAEHMGRLSSLGF--VNISVDE-----------------------ITPL--- 239

  Fly   494 AAFSGCSRTTIMGALVQQLSPFLFPCTIEYSLICAVILFEMWKTVKSIPDIDKTRKNSVKPAAAK 558
                 |:.||.:.....:...:::|..|||.::.:.:|:.:||.:          .|.:|
 Frog   240 -----CNCTTNVCHEFSKGIYYIYPFNIEYHILASAMLYVLWKNI----------GNHIK----- 284

  Fly   559 PAHHFSVDCSQSHK---GLFFGILIIVMTIISMIMYFVLYTQPGYELVATQEVTLW-ETFMYFMC 619
              ||.|....:.|.   |...|::::..||.::.:|.|...:......:...:..| ...:.|..
 Frog   285 --HHGSRKRFKLHGVAIGTILGLIVLAATIGAVFIYIVRIGRSKTSSESALTIYYWYSIIVLFAM 347

  Fly   620 AAAVITGMILMRDLRYIKNTSDEHHSMDLDNLLLIVAQTGVYLYGMFSILGSYFA------KWDT 678
            :.|.:.|:||.: |...........|:.||..||:.|.:..::....:||...|:      .|..
 Frog   348 SLASVFGLILYK-LEKKPTYQAFSPSIKLDASLLVGAASASWITAWGAILALTFSGSRLIYTWFN 411

  Fly   679 VPDRVEGIIAEVFGVVQTSLQTMFIL--------------------------------------- 704
            :|       ..|..::|..:|.:||:
 Frog   412 LP-------YSVLVIIQKYVQNIFIIDYLYCENEHTDSITLDNIEIPIPILPSEAMVTENHTAIE 469

  Fly   705 -----------------------------------------------HSSHRRCRGT-NQVRRKP 721
                                                           .|:.|..:.| :::|..|
 Frog   470 AFPEEVKEEKDGNIFLNGNTMEKNFPDNNANNNSFENNINSNEKDKTQSAQRPDKATIHKIRDSP 534

  Fly   722 G------REIITFLLVANIAIWFVNTLIKGRAVFRESHLE--FFGVWGWTIITHISMPLAIFYRF 778
            .      :.:..||.:.|:::|.....  |.....::.||  .:|...|.|:..|::|.:||||.
 Frog   535 SFRKALLKNLTVFLFLCNVSLWIPPAF--GCRPQYDNGLEALVYGFSPWIILVDIALPFSIFYRM 597

  Fly   779 HSTICLFEVW 788
            ||...||:|:
 Frog   598 HSVYSLFDVY 607

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
OtopLb	NP_608758.1	Otopetrin	330..778	CDD:281218	104/553 (19%)
otop1.2	XP_031751200.1	Otopetrin	123..431	CDD:397346	84/384 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	169	1.000	Inparanoid score	I4017
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D243107at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm9424
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X278
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.060