Protein Alignment OtopLb and otop3

DIOPT Version :9

• Sequence 1: NP_608758.1
• Gene: OtopLb / 33539
• FlyBaseID: FBgn0031514
• Length: 797
• Species: Drosophila melanogaster
• Sequence 2: NP_001106584.1
• Gene: otop3 / 100127796
• XenbaseID: XB-GENE-993899
• Length: 681
• Species: Xenopus tropicalis
• Alignment Length: 754
• Identity: 157/754 - (20%)
• Similarity: 256/754 - (33%)
• Gaps: 254/754 - (33%)

  Fly   172 RRDGNGFLSPRTAKNGNLQGTA----SGSTATINFQSGATSA--RNGSTAFFDNGAKSFQAKQQK 230
            ||...|...|......::|||.    :|..||...|.....|  .|...::.....:......|:
 Frog    42 RRGDIGQREPAAHPASHIQGTMASENTGEQATCKDQYMDLDAPGNNLEHSWLHRHCEIPTTLHQR 106

  Fly   231 DKNRRTGNDAISSALSATYCKLLVLLGVCLPITEVISDQ-IPTYVYQGFYVYLYVGSILFVIFLY 294
            .|  :||.     ..|..:...|:.||..:..:..:|:: :|....|.|...|.:.|.::.:: :
 Frog   107 AK--KTGR-----LFSGLFGLNLMFLGGTVVSSVALSNKAVPERDSQSFLCILMLLSSVWALY-H 163

  Fly   295 ISAFRNRSLFNALKDYHEKNSNVHLKHKVTHFGSFYLRVGAIAFAIGTMVYSGLEFGQ------- 352
            :...||            :|..||..|   |.|:.:|:.....|.:.:::.|..|.|.
 Frog   164 LLFIRN------------QNGAVHHDH---HAGAMWLKASLAIFGVCSIILSIFEIGHALLLQNC 213

  Fly   353 -------FFELNGHPGCRDVFVAITPICRMVLCIAQVQFIFLNTTYMDMARHKVTSRFGLMHMVA 410
                   ||.:      ..|||::..:...|.|...||.           .|.|| |:|:|..:|
 Frog   214 EILMDIVFFSI------EIVFVSVQTVLLWVSCKDCVQM-----------HHSVT-RYGIMLTLA 260

  Fly   411 TNLCEWLYVLVEETKHEIFHISQHEVDPAHDLVIHNSSMSRTDWAAVNESLHQHHHHHALNNTLV 475
            |::..||..:::::..:...|.|           .||:...:     ||
 Frog   261 TDILLWLTAVIDDSLEQDLEILQ-----------SNSTQDES-----NE---------------- 293

  Fly   476 ANVSSVIVNMTITPSPTPAAFSGCSRTTIMGALVQQLSPFLFPCTIEYSLICAVILFEMWKTVKS 540
                     |.....||.:...|..:..:.          :||..||||||||.:||.|||
 Frog   294 ---------MAQCQCPTDSMCWGLKQGYVT----------MFPFNIEYSLICATLLFIMWK---- 335

  Fly   541 IPDIDKTRKNSVKPAAAKPAHHFSVDCSQSHKGLFFGILIIVMTIISMIMYFVLYTQPGYELVAT 605
              ::.:..|....|    |.|.|.:      :|:.:|.||....::..|..||     .|::.||
 Frog   336 --NVGRREKLHSDP----PRHTFQL------RGIIYGPLIGGAALLVGISVFV-----QYQVEAT 383

  Fly   606 Q-EVTLWETFMYF-----------MCAAAVI---------------TG-----MILMRDL----- 633
            . .|::....||:           :|:.|.|               ||     .:.|.|:
 Frog   384 SGMVSILSYHMYYGYKMIILAPMIVCSVAGIIAHSLREKEKKGQKETGRSDQDWLHMEDVGSENK 448

  Fly   634 -------RYIKNTSDE--------------------------------------HHSMDLDNLLL 653
                   :|..:..||                                      :::..||..||
 Frog   449 NTDYSSGQYQSSQGDEKIQGYSLAQFALDNEKEKLEHRQGNTTKKHNTHQGKMKNYTRKLDVTLL 513

  Fly   654 IVAQTGVYLYGMFSILGSYFAKWDTVPDRVEGII---AEVFGVVQTSLQTMFILHS--------- 706
            .|:..|......|||:.:..    |.|..:...:   ..:..::|...|||||:.|
 Frog   514 FVSAVGQLGISYFSIIATVV----TTPWTMLSALNFSNSLLLILQYLSQTMFIIESMRSIHEEEK 574

  Fly   707 --------SHRR------------C--RGTNQVRRKPGREIITFLLVANIAIWFVNTLIKGRAVF 749
                    ||||            |  .|...:.|:..:|:..||::.||..|.:..........
 Frog   575 EKPGHHEESHRRMSVQEMHKAPPSCLDAGHLGLSRRVVKEMAMFLMICNIMCWILGAFGAHPLYM 639

  Fly   750 RESHLEFFGVWGWTIITHISMPLAIFYRFHSTICLFEVW 788
            .....:.:|...|..|.:|.:||::|||.||...|.||:
 Frog   640 NGLERQLYGSGIWLAILNIGLPLSVFYRMHSVGILLEVY 678

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
OtopLb	NP_608758.1	Otopetrin	330..778	CDD:281218	116/577 (20%)
otop3	NP_001106584.1	Otopetrin	185..667	CDD:281218	115/575 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	169	1.000	Inparanoid score	I4017
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D243107at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm9424
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X278
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.060