Protein Alignment CG44002 and ZBTB40

DIOPT Version :10

• Sequence 1: NP_608754.1
• Gene: CG44002 / 33535
• FlyBaseID: FBgn0264744
• Length: 345
• Species: Drosophila melanogaster
• Sequence 2: NP_055685.3
• Gene: ZBTB40 / 9923
• HGNCID: 29045
• Length: 1239
• Species: Homo sapiens
• Alignment Length: 315
• Identity: 84/315 - (26%)
• Similarity: 141/315 - (44%)
• Gaps: 42/315 - (13%)

  Fly    54 PCVKDAHNAFTIIKTYERSYQVFYEVQDT-VLEEELSEDVIIELSDSDEVILIDEQEEKVHLSEN 117
            |.::..|...::.|::.....|..|:... ||.:|..|....::|:...:...::::||. ..|:
Human   639 PAIEICHLLCSVHKSFPGLQPVMQELAYIGVLTKEDGEKETWKVSNKFHLEANNKEDEKA-AKED 702

  Fly   118 KAP--------TNEVSTQEESKTAQSDNVSEDKGHICTQCHMSFRRPGLLELHILRHHTTDGPRP 174
            ..|        |..:..|:|.:.:.|.:.:: |..||..|..||.....|::|:.|..
Human   703 SQPGEQNDQGETGSLPGQQEKEASASPDPAK-KSFICKACDKSFHFYCRLKVHMKRCR------- 759

  Fly   175 MSSTSEHAVKE--ELRTKARQLSRNSTH--------------------TCRLCNKTFCSKASCVR 217
            ::.:.:...||  |.:...::|.::...                    ||.||.:.|...:....
Human   760 VAKSKQVQCKECSETKDSKKELDKHQLEAHGAGGEPDAPKKKKKRLPVTCDLCGREFAHASGMQY 824

  Fly   218 HQKT-HTGEKPFACEICQKPFADLASVKRHLRTHTGERPFKCLTCQSAFSDGSALRQHI-RIHTG 280
            |:.| |..||||:||.|...||..:::|.|||.|||:|||.|..|...|:..|||..|. :.|:.
Human   825 HKLTEHFDEKPFSCEECGAKFAANSTLKNHLRLHTGDRPFMCKHCLMTFTQASALAYHTKKKHSE 889

  Fly   281 ERPYKCDMCDKFFRERSDARKHMMSHTAEKRFKCSQCERRFRQPKGLRRHVKLCH 335
            .:.|.|..||..|.:..:..:|:.:||.:|.:.|..|.:.|||..||..|:...|
Human   890 GKMYACQYCDAVFAQSIELSRHVRTHTGDKPYVCRDCGKGFRQANGLSIHLHTFH 944

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG44002	NP_608754.1	zf-AD	4..74	CDD:462262	3/19 (16%)
		C2H2 Zn finger	146..166	CDD:275368	6/19 (32%)
		COG5048	<162..302	CDD:227381	46/163 (28%)
		C2H2 Zn finger	202..222	CDD:275368	6/20 (30%)
		C2H2 Zn finger	230..250	CDD:275368	9/19 (47%)
		C2H2 Zn finger	258..278	CDD:275368	7/20 (35%)
		SUF4-like	282..>342	CDD:411020	18/54 (33%)
		C2H2 Zn finger	286..311	CDD:411020	7/24 (29%)
		C2H2 Zn finger	286..306	CDD:275368	5/19 (26%)
		C2H2 Zn finger	314..335	CDD:411020	8/20 (40%)
		C2H2 Zn finger	314..333	CDD:275368	8/18 (44%)
ZBTB40	NP_055685.3	BTB_POZ_ZBTB40	1..116	CDD:349534
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	130..231
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	687..732		8/45 (18%)
		C2H2 Zn finger	768..789	CDD:275368	4/20 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	779..801		1/21 (5%)
		COG5048	<794..970	CDD:227381	53/151 (35%)
		C2H2 Zn finger	809..830	CDD:275368	6/20 (30%)
		C2H2 Zn finger	838..858	CDD:275368	9/19 (47%)
		C2H2 Zn finger	866..915	CDD:275368	14/48 (29%)
		SFP1	<917..1031	CDD:227516	10/28 (36%)
		C2H2 Zn finger	923..942	CDD:275368	8/18 (44%)
		C2H2 Zn finger	952..970	CDD:275370
		SFP1	<1001..1069	CDD:227516
		C2H2 Zn finger	1008..1028	CDD:275368
		C2H2 Zn finger	1048..1066	CDD:275368
		C2H2 Zn finger	1077..1098	CDD:275368
		C2H2 Zn finger	1106..1127	CDD:275368
		C2H2 Zn finger	1137..1154	CDD:275368