DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG44002 and ZBTB14

DIOPT Version :9

Sequence 1:NP_608754.1 Gene:CG44002 / 33535 FlyBaseID:FBgn0264744 Length:345 Species:Drosophila melanogaster
Sequence 2:NP_001137295.1 Gene:ZBTB14 / 7541 HGNCID:12860 Length:449 Species:Homo sapiens


Alignment Length:291 Identity:80/291 - (27%)
Similarity:128/291 - (43%) Gaps:62/291 - (21%)


- Green bases have known domain annotations that are detailed below.


  Fly    53 PPCVKDAHNAFTIIKTYERSYQVFYEVQDTVLEEELSEDVIIELSDSDEVILIDEQEEKVHLSEN 117
            ||..:|..:..|.::           ||:.:|:|..||:|       .:|....::.|.:...|:
Human   182 PPSQEDGKSPTTTLR-----------VQEAILKELGSEEV-------RKVNCYGQEVESMETPES 228

  Fly   118 KAPTNEVSTQEESKTAQSDNVSEDK-----GHICTQCHMSFRRPGLLELHILRHHTTDGPRPMSS 177
            |    ::.:|.......:|.:||.|     |.......|.|      |..:..||          
Human   229 K----DLGSQTPQALTFNDGMSEVKDEQTPGWTTAASDMKF------EYLLYGHH---------- 273

  Fly   178 TSEHAVKEELRTKARQLSRNSTHTCRLCNKTFCSKASCVRHQKTHTGEKPFACEICQKPFADLAS 242
                  :|::             .|:.|.|||..:....:|:|.||.::||.||:|.|.|...|.
Human   274 ------REQI-------------ACQACGKTFSDEGRLRKHEKLHTADRPFVCEMCTKGFTTQAH 319

  Fly   243 VKRHLRTHTGERPFKCLTCQSAFSDGSALRQHIRIHTGERPYKCDMCDKFFRERSDARKHMMSHT 307
            :|.||:.|||.:|:.|..|..:|.....|::|.|:|:.|||:.|.||||.|:.:|..:.|...|.
Human   320 LKEHLKIHTGYKPYSCEVCGKSFIRAPDLKKHERVHSNERPFACHMCDKAFKHKSHLKDHERRHR 384

  Fly   308 AEKRFKCSQCERRFRQPKGLRRHVKLCHTDK 338
            .||.|.|..|.:.|.:...|:||....|:::
Human   385 GEKPFVCGSCTKAFAKASDLKRHENNMHSER 415

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG44002NP_608754.1 zf-AD 5..78 CDD:285071 4/24 (17%)
C2H2 Zn finger 146..166 CDD:275368 3/19 (16%)
COG5048 <162..302 CDD:227381 44/139 (32%)
C2H2 Zn finger 202..222 CDD:275368 7/19 (37%)
zf-H2C2_2 217..238 CDD:290200 10/20 (50%)
C2H2 Zn finger 230..250 CDD:275368 9/19 (47%)
zf-H2C2_2 242..266 CDD:290200 9/23 (39%)
C2H2 Zn finger 258..278 CDD:275368 6/19 (32%)
zf-H2C2_2 270..293 CDD:290200 12/22 (55%)
C2H2 Zn finger 286..306 CDD:275368 8/19 (42%)
C2H2 Zn finger 314..333 CDD:275368 6/18 (33%)
ZBTB14NP_001137295.1 BTB_POZ_ZBTB14 18..131 CDD:349513
Nuclear localization signal. /evidence=ECO:0000255 50..66
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 153..194 3/11 (27%)
C2H2 Zn finger 279..299 CDD:275368 7/19 (37%)
SFP1 <303..383 CDD:227516 33/79 (42%)
C2H2 Zn finger 307..327 CDD:275368 9/19 (47%)
zf-H2C2_2 319..344 CDD:404364 10/24 (42%)
C2H2 Zn finger 335..355 CDD:275368 6/19 (32%)
C2H2 Zn finger 363..383 CDD:275368 8/19 (42%)
C2H2 Zn finger 391..407 CDD:275368 4/15 (27%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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