DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG44002 and CG8319

DIOPT Version :9

Sequence 1:	NP_608754.1	Gene:	CG44002 / 33535	FlyBaseID:	FBgn0264744	Length:	345	Species:	Drosophila melanogaster
Sequence 2:	NP_649920.2	Gene:	CG8319 / 41165	FlyBaseID:	FBgn0037722	Length:	383	Species:	Drosophila melanogaster

Alignment Length:	383	Identity:	104/383 - (27%)
Similarity:	178/383 - (46%)	Gaps:	54/383 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MENKCRVCLASSKNMVNIFEERQDLPV---SIAHMIIECTGFKVEKGDSLPHSICPPCVKDAHNA 62
            ||:.||:|..:|:||:.||:::.:..|   .:|.|:..|...:::..|::|..:|..||.||..|
  Fly     1 MEDLCRICGGASENMLGIFDDQVEEYVDGAKLAEMVKTCADVQLDPDDAMPQKMCISCVHDARTA 65

  Fly    63 FTIIKTYERSYQVFY--EVQDTVLEEELSEDVIIELSDSDEVIL-----IDEQEEKVHLSENKAP 120
            :...:..|.:|:.||  .:...|:::|.:|:..:.:.:.|:..|     ::::.:|.|.:.::..
  Fly    66 YGFKRRCEENYKKFYLAILNGQVIKDEPNEEDFLFIENPDKGNLEAKKKLNKEIKKTHQTASRTT 130

  Fly   121 TNEVSTQEESKTAQS----------------------DNVS-EDKGHICTQCHMSFRRPGLLELH 162
            .:.::|....:..:|                      |::. ....|:|..|...|.....|:.|
  Fly   131 KSSITTSRAGRQLRSIKNQTFKCELCIKQFKRQINLLDHMKVHSNSHVCQNCEERFLFKADLDNH 195

  Fly   163 IL---RHHTTDGP---RPMSST---SEHAVKEELRTKARQLSRNSTHTCRLCNKTFCS----KAS 214
            ..   .:.|.:.|   :..|||   ..|        |.:.:...|...|..|.:.|..    ||.
  Fly   196 QCYRNSNSTVECPECLKVFSSTQSLDSH--------KCKDMQERSPFQCPHCQQAFTREQNLKAH 252

  Fly   215 CVRHQKTHTGEKPFACEICQKPFADLASVKRHLRTHTGERPFKCLTCQSAFSDGSALRQHIRIHT 279
            .:.|.::..|..|..|..||..|.:.:::|.|:..|.||||..|..|.|.|....||:.||||||
  Fly   253 LLIHAESKQGNGPHKCSYCQTGFFNKSALKVHIHAHMGERPHACPFCVSNFRSKQALKVHIRIHT 317

  Fly   280 GERPYKCDMCDKFFRERSDARKHMMSHTAEKRFKCSQCERRFRQPKGLRRHVKLCHTD 337
            ||:||:|..|.|.|.:.::..||...|:.|:.:|||.|.:.||:...|:||....|.|
  Fly   318 GEKPYQCPHCPKTFSDNNNLAKHRRRHSDERPYKCSICLQDFREKHHLKRHFLGKHRD 375

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG44002	NP_608754.1	zf-AD	5..78	CDD:285071	24/77 (31%)
		C2H2 Zn finger	146..166	CDD:275368	5/22 (23%)
		COG5048	<162..302	CDD:227381	48/152 (32%)
		C2H2 Zn finger	202..222	CDD:275368	6/23 (26%)
		zf-H2C2_2	217..238	CDD:290200	6/20 (30%)
		C2H2 Zn finger	230..250	CDD:275368	6/19 (32%)
		zf-H2C2_2	242..266	CDD:290200	10/23 (43%)
		C2H2 Zn finger	258..278	CDD:275368	9/19 (47%)
		zf-H2C2_2	270..293	CDD:290200	15/22 (68%)
		C2H2 Zn finger	286..306	CDD:275368	6/19 (32%)
		C2H2 Zn finger	314..333	CDD:275368	8/18 (44%)
CG8319	NP_649920.2	zf-AD	4..79	CDD:285071	22/74 (30%)
		COG5048	<153..368	CDD:227381	65/222 (29%)
		C2H2 Zn finger	153..173	CDD:275368	1/19 (5%)
		C2H2 Zn finger	179..196	CDD:275368	4/16 (25%)
		C2H2 Zn finger	207..227	CDD:275370	6/27 (22%)
		C2H2 Zn finger	236..256	CDD:275368	5/19 (26%)
		C2H2 Zn finger	268..288	CDD:275368	6/19 (32%)
		C2H2 Zn finger	296..316	CDD:275368	9/19 (47%)
		zf-H2C2_2	308..332	CDD:290200	15/23 (65%)
		zf-C2H2	322..344	CDD:278523	7/21 (33%)
		C2H2 Zn finger	324..344	CDD:275368	6/19 (32%)
		C2H2 Zn finger	352..368	CDD:275368	6/15 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0006715
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.910