DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG44002 and CG17359

DIOPT Version :9

Sequence 1:	NP_608754.1	Gene:	CG44002 / 33535	FlyBaseID:	FBgn0264744	Length:	345	Species:	Drosophila melanogaster
Sequence 2:	NP_648679.1	Gene:	CG17359 / 39549	FlyBaseID:	FBgn0036396	Length:	339	Species:	Drosophila melanogaster

Alignment Length:	368	Identity:	100/368 - (27%)
Similarity:	166/368 - (45%)	Gaps:	91/368 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 CRVCLASSKNMVNIFEE--------RQDLPVSIAHMIIECTGFKVEKGDSLPHSICPPCVKDAHN 61
            ||||...|..:::|:.|        ::..|| :|.|:.||:|..|.|.|.:|..||..|.:...|
  Fly     7 CRVCRDESDCLLDIYTEPYASSNRVQEQEPV-LATMLRECSGCSVHKEDGMPQFICVECAEAVRN 70

  Fly    62 AFTIIKTYERSYQVFYEVQDTVLEEELSEDVIIELSDSDEVILIDEQEEKVHLSENKAPTNEVST 126
            |:.:.:...:|:|.|.:::  ::.:||                 |:.|..:::.:|..|...||.
  Fly    71 AYRLRRQCRKSHQYFEQLR--LMMKEL-----------------DDIEYCLNIGDNIEPQMPVSV 116

  Fly   127 QEESKTAQSDNVSEDKGHICTQCHMSFRRPGLLELHILRHHTTDGPRPMSS----TSEHAVKE-- 185
            .|..||.::.                  .|.|:||..:::...: |:|:||    .:||.:.:
  Fly   117 MEAGKTPETS------------------EPLLVELVQVKYMPPE-PKPISSPLPDNNEHKLAQSY 162

  Fly   186 --------ELRTKARQLSRNST------------------------------HTCRLCNKTFCSK 212
                    :.:.:||..|.|.:                              :.|:||.::|..|
  Fly   163 SPAKTPHNKSKRRARSYSDNDSWSPDSELEHEDDDKIWNASKRGKPKRVPGPYRCKLCTQSFTQK 227

  Fly   213 ASCVRHQKTHTGEKPFACEICQKPFADLASVKRHLRTHTGERPFKCLTCQSAFSDGSALRQHIRI 277
            .:...|.:.||||:|:.|.:|.:.||...:::.|.|.|||||||.|..|...|.....|:.|.|.
  Fly   228 QNLEIHMRIHTGERPYKCSLCPRSFAQKGNLQSHTRCHTGERPFGCPNCPKRFRQVGQLQVHTRT 292

  Fly   278 HTGERPYKCDMCDKFFRERSDARKHMMSHTAEKRFKCSQCERR 320
            ||||:|:||..|.:.|::.:..:|||.:||..||...||..:|
  Fly   293 HTGEQPFKCSKCQQSFKQLNGLQKHMSAHTRGKRRTSSQETKR 335

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG44002	NP_608754.1	zf-AD	5..78	CDD:285071	26/80 (33%)
		C2H2 Zn finger	146..166	CDD:275368	4/19 (21%)
		COG5048	<162..302	CDD:227381	49/183 (27%)
		C2H2 Zn finger	202..222	CDD:275368	6/19 (32%)
		zf-H2C2_2	217..238	CDD:290200	8/20 (40%)
		C2H2 Zn finger	230..250	CDD:275368	6/19 (32%)
		zf-H2C2_2	242..266	CDD:290200	11/23 (48%)
		C2H2 Zn finger	258..278	CDD:275368	6/19 (32%)
		zf-H2C2_2	270..293	CDD:290200	11/22 (50%)
		C2H2 Zn finger	286..306	CDD:275368	6/19 (32%)
		C2H2 Zn finger	314..333	CDD:275368	3/7 (43%)
CG17359	NP_648679.1	zf-AD	6..88	CDD:285071	26/81 (32%)
		zf-C2H2	215..237	CDD:278523	6/21 (29%)
		C2H2 Zn finger	217..237	CDD:275368	6/19 (32%)
		zf-H2C2_2	229..254	CDD:290200	9/24 (38%)
		C2H2 Zn finger	245..265	CDD:275368	6/19 (32%)
		zf-H2C2_2	257..282	CDD:290200	12/24 (50%)
		C2H2 Zn finger	273..293	CDD:275368	6/19 (32%)
		zf-H2C2_2	286..310	CDD:290200	12/23 (52%)
		C2H2 Zn finger	301..321	CDD:275368	6/19 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.910