DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG44002 and Zbtb6

DIOPT Version :9

Sequence 1:	NP_608754.1	Gene:	CG44002 / 33535	FlyBaseID:	FBgn0264744	Length:	345	Species:	Drosophila melanogaster
Sequence 2:	NP_001102423.1	Gene:	Zbtb6 / 366029	RGDID:	1306007	Length:	423	Species:	Rattus norvegicus

Alignment Length:	338	Identity:	88/338 - (26%)
Similarity:	136/338 - (40%)	Gaps:	83/338 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 MIIEC-TG-FKVEKGDSLPHSICPPCVKDAHNAFTIIKTYERSYQVFYEV-------QDTVLEEE 87
            :::.| || .:|::.:.|.:......::..|    |::....:...:.|:       |.|.|.:.
  Rat    84 LLLSCYTGALEVKRKELLKYLTAASYLQMVH----IVEKCTEALSKYLEIDLSMKNNQHTDLCQS 144

  Fly    88 LSEDVIIELSDSD---EVILIDE----------QEEKVHLSENKAPTNEVSTQEESKTAQSDNVS 139
            ...||..|..:||   |:|.|.|          :||:....::.|.|    ...|.:..:|..:|
  Rat   145 SDTDVKNEEENSDKDCEIIEISEDSPVNLDPPVKEEEGDALQSAAET----LTSERRGVKSPELS 205

  Fly   140 EDKGHICTQCHMSFRRPGLLELHILRHHTTD-----GPRP-----------------MSSTSEHA 182
            ...|        .|:...:..||:...||.|     .|:|                 ::||.|:.
  Rat   206 TVDG--------GFKENEICILHVESIHTDDIENGQFPQPCTSSNAGMYFPETQHSVINSTVENR 262

  Fly   183 VKE-ELRTKARQLSRNS-------------------THTCRLCNKTFCSKASCVRHQKTHTGEKP 227
            |.| ...|.....|.||                   .|.|..|.:.|....:.:||.|.|   |.
  Rat   263 VTEVPGNTNQGLFSENSDGSHGTINEIQNLDENFSLRHQCPRCPRGFLHVENYLRHLKMH---KL 324

  Fly   228 FACEICQKPFADLASVKRHLRTHTGERPFKCLTCQSAFSDGSALRQHIRIHTGERPYKCDMCDKF 292
            |.|..|.|.|....::.||:|.|.|.|||:|..|...|:..|.|:.|:.||:|:|||||..||..
  Rat   325 FLCLQCGKTFTQKKNLNRHIRGHMGIRPFQCTVCLKTFTAKSTLQDHLNIHSGDRPYKCHCCDMD 389

  Fly   293 FRERSDARKHMMS 305
            |:.:|..:||:.|
  Rat   390 FKHKSALKKHLTS 402

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG44002	NP_608754.1	zf-AD	5..78	CDD:285071	7/47 (15%)
		C2H2 Zn finger	146..166	CDD:275368	3/19 (16%)
		COG5048	<162..302	CDD:227381	55/181 (30%)
		C2H2 Zn finger	202..222	CDD:275368	6/19 (32%)
		zf-H2C2_2	217..238	CDD:290200	9/20 (45%)
		C2H2 Zn finger	230..250	CDD:275368	7/19 (37%)
		zf-H2C2_2	242..266	CDD:290200	10/23 (43%)
		C2H2 Zn finger	258..278	CDD:275368	6/19 (32%)
		zf-H2C2_2	270..293	CDD:290200	12/22 (55%)
		C2H2 Zn finger	286..306	CDD:275368	8/20 (40%)
		C2H2 Zn finger	314..333	CDD:275368
Zbtb6	NP_001102423.1	BTB_POZ_ZBTB6	8..123	CDD:349506	7/42 (17%)
		COG5048	<251..>398	CDD:227381	49/149 (33%)
		C2H2 Zn finger	302..322	CDD:275368	6/19 (32%)
		zf-C2H2	325..347	CDD:395048	8/21 (38%)
		C2H2 Zn finger	327..347	CDD:275368	7/19 (37%)
		zf-H2C2_2	339..363	CDD:404364	10/23 (43%)
		C2H2 Zn finger	355..375	CDD:275368	6/19 (32%)
		C2H2 Zn finger	383..400	CDD:275368	6/16 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910