DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG44002 and CG17612

DIOPT Version :9

Sequence 1:	NP_608754.1	Gene:	CG44002 / 33535	FlyBaseID:	FBgn0264744	Length:	345	Species:	Drosophila melanogaster
Sequence 2:	NP_608824.1	Gene:	CG17612 / 33639	FlyBaseID:	FBgn0031597	Length:	618	Species:	Drosophila melanogaster

Alignment Length:	352	Identity:	97/352 - (27%)
Similarity:	147/352 - (41%)	Gaps:	85/352 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 CRVCLASSKNMVNIFEERQDLPVSIAHMIIECTGFKVEKGDSLPHSICPPCVKDAHNAFTIIKTY 69
            |||||..|.|:.|||::.....:.||.::.:.||..||||||....||..|:....|||..:::.
  Fly   187 CRVCLEQSDNLTNIFDDAHQYGIPIATILSQYTGMPVEKGDSFSEYICVTCLDVVKNAFDDLESK 251

  Fly    70 ERSYQVFYEVQDTVLEEELSEDVIIELSDSDEVILIDEQEEKVHLSENKAPTNEVSTQEESKTAQ 134
            |.:.|::.:.::             |:.|.|.:.:           :||....||:.:..
  Fly   252 ENTIQMYRQPKE-------------EIIDIDSIPV-----------KNKPVDYEVTGKPP----- 287

  Fly   135 SDNVSEDKGHICTQCHMSFRRPGLLELHILRHH---TTDGPRPMSSTSEHAVKEELRTKARQLSR 196
                     |.|.||...|.....|:.||..|:   ||:.||             |:
  Fly   288 ---------HRCPQCPKIFLLAAKLQAHIRTHNETRTTEPPR-------------LK-------- 322

  Fly   197 NSTHTCRLCNKTFCSKASCVRHQKTHTG--------EKPFACEICQKPFADLASVKRHLRTH--- 250
                 |.:|...:..:.....|...|..        |.|:.|..|.|.|...:.::.|::||
  Fly   323 -----CPMCPSIYMKRGCLEAHMWIHRASDERESELEPPYRCPHCPKLFLYSSFLEIHIQTHEDV 382

  Fly   251 ----TGERPFKCLTCQSAFSDGSALRQHIRIHTGERPYKCDMCDKFFRERSDARKHMMSHTAEKR 311
                :.:...||..|...|||.|:|:.|::||.|||.:||.:|...|:|.|:.:.|..:||   |
  Fly   383 SQRLSRKSSHKCAQCADVFSDVSSLKDHVKIHAGERTFKCPLCLMSFQEESNLKSHDCAHT---R 444

  Fly   312 FKCSQCERRFRQPKGLRRHVKLCHTDK 338
            |||.:|.:.|.....|..|.|..||.|
  Fly   445 FKCHKCSKFFESQNYLDFHFKKSHTTK 471

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG44002	NP_608754.1	zf-AD	5..78	CDD:285071	28/72 (39%)
		C2H2 Zn finger	146..166	CDD:275368	7/19 (37%)
		COG5048	<162..302	CDD:227381	41/157 (26%)
		C2H2 Zn finger	202..222	CDD:275368	3/19 (16%)
		zf-H2C2_2	217..238	CDD:290200	7/28 (25%)
		C2H2 Zn finger	230..250	CDD:275368	5/19 (26%)
		zf-H2C2_2	242..266	CDD:290200	6/30 (20%)
		C2H2 Zn finger	258..278	CDD:275368	8/19 (42%)
		zf-H2C2_2	270..293	CDD:290200	10/22 (45%)
		C2H2 Zn finger	286..306	CDD:275368	6/19 (32%)
		C2H2 Zn finger	314..333	CDD:275368	5/18 (28%)
CG17612	NP_608824.1	zf-AD	187..>246	CDD:285071	25/58 (43%)
		C2H2 Zn finger	290..310	CDD:275368	7/19 (37%)
		C2H2 Zn finger	323..343	CDD:275370	3/19 (16%)
		zf-C2H2_8	356..438	CDD:292531	28/81 (35%)
		C2H2 Zn finger	359..379	CDD:275368	5/19 (26%)
		C2H2 Zn finger	394..414	CDD:275368	8/19 (42%)
		C2H2 Zn finger	422..438	CDD:275368	5/15 (33%)
		C2H2 Zn finger	447..463	CDD:275368	4/15 (27%)
		C2H2 Zn finger	476..505	CDD:275368
		C2H2 Zn finger	513..533	CDD:275368
		C2H2 Zn finger	545..565	CDD:275368
		C2H2 Zn finger	568..584	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	116	1.000	Inparanoid score	I3381
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0006715
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.960