DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG44002 and Zbtb26

DIOPT Version :9

Sequence 1:	NP_608754.1	Gene:	CG44002 / 33535	FlyBaseID:	FBgn0264744	Length:	345	Species:	Drosophila melanogaster
Sequence 2:	NP_950190.2	Gene:	Zbtb26 / 320633	MGIID:	2444402	Length:	440	Species:	Mus musculus

Alignment Length:	310	Identity:	74/310 - (23%)
Similarity:	125/310 - (40%)	Gaps:	79/310 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 VSIAHMIIECTG--FKV--------EKGDSLPHSICP-----------------PCVKDAHNAFT 64
            :.::|::..||.  :|.        .|..|.|.|..|                 ||:..:.::.
Mouse   110 LQMSHIVERCTQALWKFIKPKQPMDSKEGSEPQSASPQSKEQQGDARGSPKQDLPCIHPSEDSM- 173

  Fly    65 IIKTYERSYQVFYEVQDT---VLEEELSEDVIIELSDSDEVILIDEQEEKVHLSENKAPTNEV-- 124
                         :::|:   :::.|...||..:.|..||...|..:...:|.||   |.:.:
Mouse   174 -------------DMEDSDIQIVKVESIGDVSEDRSKKDENQYISSEPTALHSSE---PQHSLIN 222

  Fly   125 STQEESKTAQSDNVSE-DKGHICTQCHMSFRRPGLLELHILRHHTTDGPRPMSSTSEHAVKEELR 188
            ||.|       :.|:| |:.|              |..:.|.:...|   .:..||:......:|
Mouse   223 STVE-------NRVNELDQSH--------------LHNYALSYTGND---DIIMTSKDVFGPNIR 263

  Fly   189 TKARQLSRNSTHTCRLCNKTFCSKASCVRHQKTHTGEKPFACEICQKPFADLASVKRHLRTHTGE 253
            ...:.|..:  |.|..|.:.|....:...|.|.|   |.|.|.:|.|.|....::.||:|.|.|.
Mouse   264 GVDKGLQWH--HQCPKCTRVFRHLENYANHLKMH---KLFMCLLCGKTFTQKGNLHRHMRVHAGI 323

  Fly   254 RPFKCLTCQSAFSDGSALRQHIRIHTGERPYKCDMCDKFFRERSDARKHM 303
            :||:|..|...||...:|:.|:.:|:|::|:||:.||..|..:...|||:
Mouse   324 KPFQCKICGKTFSQKCSLQDHLNLHSGDKPHKCNYCDMVFAHKPVLRKHL 373

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG44002	NP_608754.1	zf-AD	5..78	CDD:285071	11/77 (14%)
		C2H2 Zn finger	146..166	CDD:275368	2/19 (11%)
		COG5048	<162..302	CDD:227381	41/139 (29%)
		C2H2 Zn finger	202..222	CDD:275368	5/19 (26%)
		zf-H2C2_2	217..238	CDD:290200	8/20 (40%)
		C2H2 Zn finger	230..250	CDD:275368	7/19 (37%)
		zf-H2C2_2	242..266	CDD:290200	9/23 (39%)
		C2H2 Zn finger	258..278	CDD:275368	6/19 (32%)
		zf-H2C2_2	270..293	CDD:290200	9/22 (41%)
		C2H2 Zn finger	286..306	CDD:275368	7/18 (39%)
		C2H2 Zn finger	314..333	CDD:275368
Zbtb26	NP_950190.2	BTB	23..123	CDD:306997	3/12 (25%)
		C2H2 Zn finger	275..295	CDD:275368	5/19 (26%)
		zf-C2H2	298..320	CDD:306579	8/21 (38%)
		C2H2 Zn finger	300..320	CDD:275368	7/19 (37%)
		zf-H2C2_2	315..337	CDD:316026	10/21 (48%)
		C2H2 Zn finger	328..348	CDD:275368	6/19 (32%)
		zf-H2C2_2	340..365	CDD:316026	10/24 (42%)
		C2H2 Zn finger	356..374	CDD:275368	7/18 (39%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910