DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG44002 and ZNF648

DIOPT Version :9

Sequence 1:NP_608754.1 Gene:CG44002 / 33535 FlyBaseID:FBgn0264744 Length:345 Species:Drosophila melanogaster
Sequence 2:NP_001009992.1 Gene:ZNF648 / 127665 HGNCID:18190 Length:568 Species:Homo sapiens


Alignment Length:301 Identity:84/301 - (27%)
Similarity:128/301 - (42%) Gaps:57/301 - (18%)


- Green bases have known domain annotations that are detailed below.


  Fly    43 KGDSLPHSICPPCVKDAHNAFTI-----IKTYERSYQVFYEVQDTVLEEELSEDVIIELSDSDEV 102
            :|.:.....|..|.|...:..|:     :.|.||.||..:           .:......||..:.
Human   272 RGGAAKRYACELCGKAYSHRGTLQQHRRLHTGERPYQCSF-----------CDKAYTWSSDHRKH 325

  Fly   103 ILIDEQEEKVHLSENKAPTNEVS----TQEESKTAQSDNVSEDKGHICTQCHMSFRRPGLLELHI 163
            |       :.|..|...|..:..    ...:.:..|.:..|.:|...|::|.::|.:|    |.:
Human   326 I-------RTHTGEKPYPCPDCGKAFVRSSDLRKHQRNMHSNNKPFPCSECGLTFNKP----LSL 379

  Fly   164 LRHHTTD-GPRPMSSTSEHAVKEELRTKARQLSRNSTHTCRLCNKTFCSKASCVRHQKTHTGEKP 227
            |||..|. |.:|.                         .|..|::.|...:..|.||:.|:||:|
Human   380 LRHQRTHLGAKPF-------------------------RCPACDREFAVASRMVEHQRVHSGERP 419

  Fly   228 FACEICQKPFADLASVKRHLRTHTGERPFKCLTCQSAFSDGSALRQHIRIHTGERPYKCDMCDKF 292
            |.|..|.|.|...:::..|...|||:|||||..|..||:..|.|.:|.||||||||:.|..|.:.
Human   420 FPCPTCGKCFTKSSNLSEHQTLHTGQRPFKCADCGVAFAQPSRLVRHQRIHTGERPFPCTQCGQA 484

  Fly   293 FRERSDARKHMMSHTAEKRFKCSQCERRFRQPKGLRRHVKL 333
            |...|..::|...|:.||.|.|::|.|.||....|.:|:::
Human   485 FARSSTLKRHQQIHSGEKGFLCAECGRAFRIASELAQHIRM 525

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG44002NP_608754.1 zf-AD 5..78 CDD:285071 10/39 (26%)
C2H2 Zn finger 146..166 CDD:275368 6/19 (32%)
COG5048 <162..302 CDD:227381 48/140 (34%)
C2H2 Zn finger 202..222 CDD:275368 6/19 (32%)
zf-H2C2_2 217..238 CDD:290200 10/20 (50%)
C2H2 Zn finger 230..250 CDD:275368 5/19 (26%)
zf-H2C2_2 242..266 CDD:290200 11/23 (48%)
C2H2 Zn finger 258..278 CDD:275368 8/19 (42%)
zf-H2C2_2 270..293 CDD:290200 12/22 (55%)
C2H2 Zn finger 286..306 CDD:275368 5/19 (26%)
C2H2 Zn finger 314..333 CDD:275368 7/18 (39%)
ZNF648NP_001009992.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..106
C2H2 Zn finger 281..301 CDD:275368 4/19 (21%)
zf-H2C2_2 294..317 CDD:316026 5/33 (15%)
COG5048 <307..494 CDD:227381 64/233 (27%)
C2H2 Zn finger 309..329 CDD:275368 3/37 (8%)
C2H2 Zn finger 337..355 CDD:275368 0/17 (0%)
C2H2 Zn finger 366..386 CDD:275368 8/23 (35%)
C2H2 Zn finger 394..414 CDD:275368 6/19 (32%)
C2H2 Zn finger 422..442 CDD:275368 5/19 (26%)
C2H2 Zn finger 450..470 CDD:275368 8/19 (42%)
C2H2 Zn finger 478..498 CDD:275368 5/19 (26%)
C2H2 Zn finger 506..526 CDD:275368 7/20 (35%)
zf-H2C2_2 518..543 CDD:316026 2/8 (25%)
C2H2 Zn finger 534..554 CDD:275368
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 548..568
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 1 0.950 - 0 Normalized mean entropy S5354
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.950

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